BFR do not deflate for Medial Patellar Femoral Ligament Reconstruction Rehabilitation

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of Kentucky Sports Rehabilitation, Lexington, KY
Medial Patellar Femoral Ligament Reconstruction Rehabilitation+1 More
Rehabilitation utilizing blood flow restrictive therapy - Other
Eligibility
< 65
All Sexes
What conditions do you have?
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Study Summary

Blood flow restrictive (BFR) therapy following MPFL or ACL reconstruction rehabilitation. Specific Aim 1: Test whether maintaining BFR cuff inflation or deflating between exercises results in greater quadriceps strength and functional outcomes after MPFL or ACL reconstruction. Hypothesis 1: Subjects in the deflate BFR protocol group will have significantly greater quadriceps strength, symmetric leg symmetry index on a battery of functional tests and PROs as compared to the non-deflate group. Specific Aim 2: Compare whether maintaining BFR cuff inflation or deflating between exercises results in reduced pain, improved exercise tolerance, and patient-reports outcomes (PRO) after MPFL or ACL reconstruction. Hypothesis 2: Subjects in the deflated BFR protocol group will report significantly less pain and greater exercise tolerance during exercise with significantly improved knee related PRO scores.

Eligible Conditions

  • Medial Patellar Femoral Ligament Reconstruction Rehabilitation
  • Reconstructive Surgical Procedures

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

10 Primary · 2 Secondary · Reporting Duration: 24th visit or 12 weeks Post-op (if missed appointments)

Week 12
Quadriceps Isometric Knee Strength
Measured at each treatment follwoing each BFR exercise - Specific Aim 2
Discomfort level
Effort Level
Week 12
Norwich Patellar Instability
Week 12
2000 IKDC Subjective Knee Evaluation Form
Brief Resiliency Scale
Lower Extremity Functional Scale (LEFS)
Week 12
Ability to in-line jog
Hip abduction Isometric Strength
Max core strength assessment
Maximum 6 inch forward step down test
Y Balance Anterior Reach Test

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

BFR do not deflate
1 of 2
BFR deflate
1 of 2
Active Control

32 Total Participants · 2 Treatment Groups

Primary Treatment: BFR do not deflate · No Placebo Group · N/A

BFR do not deflate
Other
ActiveComparator Group · 1 Intervention: Rehabilitation utilizing blood flow restrictive therapy · Intervention Types: Other
BFR deflate
Other
ActiveComparator Group · 1 Intervention: Rehabilitation utilizing blood flow restrictive therapy · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 24th visit or 12 weeks post-op (if missed appointments)
Closest Location: University of Kentucky Sports Rehabilitation · Lexington, KY
Photo of Lexington 1Photo of Lexington 2Photo of Lexington 3
N/AFirst Recorded Clinical Trial
1 TrialsResearching Medial Patellar Femoral Ligament Reconstruction Rehabilitation
0 CompletedClinical Trials

Who is running the clinical trial?

Richard Watson, PTLead Sponsor

Eligibility Criteria

Age < 65 · All Participants · 1 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.