Radiofrequency ablation (RFA) for Chronic Rhinitis

The University of Texas Health Science Center at Houston, Houston, TX
Chronic RhinitisRadiofrequency ablation (RFA) - Device
18 - 80
All Sexes
What conditions do you have?

Study Summary

This trial assesses the effectiveness of a procedure to treat chronic rhinitis by comparing patient symptoms, airflow and cytokines before and after.

Eligible Conditions
  • Chronic Rhinitis

Treatment Effectiveness

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: Baseline,12 weeks post intervention

Week 12
Change in nasal congestion as assessed by the peak nasal inspiratory flow (PNIF)
Baseline,12 weeks post intervention
Change in levels of type 2 cytokines
Change in nasal congestion as assessed by the reflective total nasal symptom score (rTNSS)
Change in nasal obstruction as assessed by the nasal obstruction symptom evaluation survey (NOSE)

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

Radiofrequency ablation (RFA)
1 of 1

Experimental Treatment

36 Total Participants · 1 Treatment Group

Primary Treatment: Radiofrequency ablation (RFA) · No Placebo Group · N/A

Radiofrequency ablation (RFA)
Experimental Group · 1 Intervention: Radiofrequency ablation (RFA) · Intervention Types: Device
First Studied
Drug Approval Stage
How many patients have taken this drug
Radiofrequency ablation (RFA)
Completed Phase 2

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline,12 weeks post intervention

Who is running the clinical trial?

The University of Texas Health Science Center, HoustonLead Sponsor
833 Previous Clinical Trials
263,261 Total Patients Enrolled
American Academy of Otolaryngic Allergy & FoundationUNKNOWN
1 Previous Clinical Trials
33 Total Patients Enrolled
David Z Allen, MDPrincipal InvestigatorThe University of Texas Health Science Center, Houston

Eligibility Criteria

Age 18 - 80 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have been experiencing symptoms of chronic rhinitis such as runny nose, congestion, and post-nasal drip for at least 6 months.
You have tried medical treatment for at least 4 weeks, but it did not improve your condition.

Frequently Asked Questions

Is this trial still recruiting participants?

"Based on the information found on, this particular study is no longer enrolling patients as it was last edited over a month ago. However, an array of 66 other trials are presently recruiting across various medical centres." - Anonymous Online Contributor

Unverified Answer

Are there any elderly participants in this experimentation?

"Those between 18 and 65 years old are eligible to apply for this clinical trial. However, there are 24 trials available for those younger than 18 and 45 studies targeting patients over the age of 65." - Anonymous Online Contributor

Unverified Answer

Is there still an opportunity to enroll in this clinical experiment?

"This clinical study requires 36 individuals suffering from rhinitis between 18 and 65. To be eligible, hopefuls must have had symptoms of chronic rhinitis for at least 6 months (runny nose, congestion, post-nasal drip), attempted medical management with no effect lasting 4 weeks or more, a rTNSS score ≥6 inclusive of >=2 in regards to runny nose and 1+ concerning nasal blockage." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.