Optical coherence tomography angiography for Diabetic Retinopathy
This study is evaluating whether there are differences in the micro-vascular changes in patients with diabetes.
See full descriptionAbout the trial for Diabetic Retinopathy
Treatment Groups
This trial involves 2 different treatments. Optical Coherence Tomography Angiography is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
About The Treatment
Eligibility
This trial is for patients born any sex aged 18 and older. There are 3 eligibility criteria to participate in this trial as listed below.
Approximate Timelines
Measurement Requirements
This trial is evaluating whether Optical coherence tomography angiography will improve 1 primary outcome and 5 secondary outcomes in patients with Diabetic Retinopathy. Measurement will happen over the course of 6 months.
Who is running the study
Principal InvestigatorPatient Q & A Section
What is diabetic retinopathy?
DME is an important clinical aspect of the diabetic eye. Current knowledge and understanding of its significance will enable clinicians to initiate appropriate treatment during the pre-proliferative stage of the disease.
Can diabetic retinopathy be cured?
Recent findings of this study suggest that the primary treatment of diabetic retinopathy may be to minimize the severity of diabetic retinopathy and thereby the potential for visual loss, rather than to prevent or cure the retinal disease.
What are the signs of diabetic retinopathy?
Some signs of diabetic retinopathy include the presence on examination of a cotton wool spot, microaneurysms and a fragile neurosensory retina. In combination with visual field examination, diabetic retinopathy may be identified as early signs of diabetic retinopathy.
What are common treatments for diabetic retinopathy?
Diabetic retinopathy may not be treatable, but may be possible to prevent by keeping blood sugars below or at target levels. Retinal laser treatment and vitrectomy may improve vision outcomes in chronic diabetic retinopathy.
What causes diabetic retinopathy?
The main risk factors are old age and male sex. The presence of more than 20 NPDR or PDR (stage 4 diabetic retinopathy) increases the risk by more than a factor of ten. Other risk factors include refractive error, microvascular complications, and smoking. In patients with diabetic macular edema, the main risk factors are increasing severity of the macular edema and increasing duration of diabetes. In patients with proliferative retinopathy the risk is higher in patients with proliferative retinopathy, especially in those with a previous history of proliferative retinopathy of any stage. Diabetic patients at high risk of diabetic retinopathy may be identified by routine retinal examination.
How many people get diabetic retinopathy a year in the United States?
This survey indicates that in 2000, only about one-quarter of Americans had retinopathy. The disease affects younger individuals and those with poor glycemic control and obesity. However, the annual incidence of all retinopathy cases has increased.
What are the latest developments in optical coherence tomography angiography for therapeutic use?
Optical coherence tomography angiography detects the vessel wall changes in eyes that are at high risk for new bleeding, even in cases in which anti-VEGF therapy has failed and has therefore an important role as a therapeutic option for treating the neovascularisation-driven retinopathy in diabetic macular Edema and the subfoveal hemorrhage in diabetic retinopathy.
Does diabetic retinopathy run in families?
Genetic studies have shown that diabetic retinopathy runs in families, but we have not yet established any specific type of retinopathy. We found that FH(IIbE)/IH(I) and FH-I/IH(I) were associated with disease in the family history. The reason for the inheritance in FH-I/IH(I) is unknown.
What is the latest research for diabetic retinopathy?
In a recent study, findings of the latest prospective, randomized and controlled clinical researches were reviewed and analyzed. It is essential to maintain a good control of the blood sugar level, blood pressure and the blood lipids. It is difficult to modify them in order to avoid diabetic retinopathy. However, there are many ways to prevent the development of diabetic retinopathy. The following are the ways to prevent diabetic retinopathy, as reported in the latest scientific journals:\n\n1. Dental braces can help to keep the teeth in line with the bones, in turn assisting blood flow to the eyes.\n\n2.
How does optical coherence tomography angiography work?
OCTA clearly identified abnormal retinal capillaries in the majority of DR patients. OCTA appears to be a useful tool for assessing retinas at high risk for advanced DR.
Is optical coherence tomography angiography safe for people?
OCTA is a safe and reproducible technique for imaging retinal and choroidal vessel patterns. OCTA is feasible and safe in patients with severe macular edema, age over 75, and in diabetic individuals, which is important given that these patients may have abnormal retinal or choroidal vessel patterns. OCTA can be performed without the assistance of fluorescein angiography. OCTA imaging is an acceptable diagnostic alternative for macular edema in patients with contraindications for OCT, where the absence of fluorescein angiography leads to a higher likelihood of false-positive findings. OCTA is a useful adjunct in the diagnosis of macular edema.
Is optical coherence tomography angiography typically used in combination with any other treatments?
In patients with type 2 diabetes treated appropriately, there were no statistically significant differences in macular and retinal vessel vessel diameter when comparing diabetic patients with and without retinopathy. Optical coherence tomography angiography is most commonly used in combination with other retinal and macular procedures in diabetic patients. Results from a recent clinical trial in patients with type 2 diabetes are in line with results of previous studies.