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Swept Source Optical Coherence Tomography Angiography for Cardiovascular Disease

N/A

Recruiting

Led By Rukhsana Mirza, MD

Research Sponsored by Northwestern University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 hours

Awards & highlights

Study Summary

This trial will test whether abnormalities in the retina's blood vessels, as seen on a special kind of OCT scan, are linked with the severity of cardiovascular disease as measured by ultrasound of the carotid arteries.

Who is the study for?

This trial is for adults aged 18-80 who are being checked for heart disease and can undergo a clinical eye exam. They must be able to consent, not have any known eye diseases except for needing glasses or contacts, and should be getting standard carotid artery scans.Check my eligibility

What is being tested?

The study is testing if a special type of eye scan called SS-OCTA can show changes in the tiny blood vessels of the retina that match up with how severe someone's heart disease is, as seen on neck artery ultrasounds.See study design

What are the potential side effects?

SS-OCTA is generally safe but may cause discomfort from bright lights or sitting still during the scan. There's also a small risk of temporary blurry vision after the test.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Correlation with and prediction of the presence/degree of carotid occlusive disease as determined by carotid duplex ultrasonography

Trial Design

1Treatment groups

Experimental Treatment

Group I: All ParticipantsExperimental Treatment1 Intervention

50 participants identified in the Northwestern Medicine Division of Vascular Surgery.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Northwestern UniversityLead Sponsor

1,585 Previous Clinical Trials

917,181 Total Patients Enrolled

Rukhsana Mirza, MDPrincipal InvestigatorNorthwestern University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this trial enrolling people under the age of 35?

"According to the trial's eligibility requirements, participants must be 18 or over but no older than 80 years of age."

Answered by AI

How many participants are included in this medical research?

"Affirmative. As per the clinicaltrials.gov record, this experiment is actively recruiting patients since its posting on August 17th 2021 and subsequent update in October 26th 2021. 50 trial participants are required at a single site to complete enrollment."

Answered by AI

For whom does this clinical trial provide eligibility criteria?

"This medical study is seeking 50 volunteers with cardiovascular issues, aged between 18 and 80. In order to participate in the trial, candidates must meet all of the following requirements: they should be within the specified age range; have not had any prior retinal diseases; able to attend an eye examination appointment; consenting to take part; and receiving usual carotid duplex ultrasound treatment."

Answered by AI

Are there still vacancies available for patients to join this research trial?

"Yes, the details hosted on clinicaltrials.gov communicate that this medical trial is open for patients to join. This experiment was first announced on August 17th 2021 and has been revised as of October 26th 2021."

Answered by AI

Recent research and studies

American Journal of EpidemiologyJournal

Relation of Retinopathy to Coronary Artery Calcification: The Multi-ethnic Study of Atherosclerosis

Wong, T. Y., N. Cheung, F. M. A. Islam, R. Klein, M. H. Criqui, M. F. Cotch, J. J. Carr, B. E. K. Klein, and A. R. Sharrett. 2007. “Relation of Retinopathy to Coronary Artery Calcification: The Multi-ethnic Study of Atherosclerosis”. American Journal of Epidemiology. Oxford University Press (OUP). doi:10.1093/aje/kwm256.

HypertensionJournal

Relationship Between Retinal Arteriolar Narrowing and Myocardial Perfusion

Wang, Lu, Tien Y. Wong, A. Richey Sharrett, Ronald Klein, Aaron R. Folsom, and Michael Jerosch-Herold. 2008. “Relationship Between Retinal Arteriolar Narrowing and Myocardial Perfusion”. Hypertension. Ovid Technologies (Wolters Kluwer Health). doi:10.1161/hypertensionaha.107.098343.

Physical TherapyJournal

Cade, W Todd. 2008. “Diabetes-related Microvascular and Macrovascular Diseases in the Physical Therapy Setting”. Physical Therapy. Oxford University Press (OUP). doi:10.2522/ptj.20080008.

The American Journal of MedicineJournal

The Relationship Between Retinal Microvascular Abnormalities and Coronary Heart Disease: A Review