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Baseline, post e-cigarette without nicotine and post e-cigarette with nicotine for Vaping

N/A

Waitlist Available

Led By Christian Casanova, PhD

Research Sponsored by Christian Casanova

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up at baseline, approximately 13 after baseline and after approximately 28 minutes after baseline

Awards & highlights

Study Summary

This trial will investigate if electronic cigarettes can have harmful effects on health, such as breathing difficulties, lung inflammation, and vascular changes.

Eligible Conditions

Vaping
Retinopathy

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ at baseline, approximately 13 after baseline and after approximately 28 minutes after baseline

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~at baseline, approximately 13 after baseline and after approximately 28 minutes after baseline

This trial's timeline: 3 weeks for screening, Varies for treatment, and at baseline, approximately 13 after baseline and after approximately 28 minutes after baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in eye fundus tissue oxygen saturation between baseline, after use of e-cigarette without nicotine and after use of e-cigarette with nicotine

Change in retinal capillaries density between between baseline, after use of e-cigarette without nicotine and after use of e-cigarette with nicotine

Change in retinal electric activity between baseline, after use of e-cigarette without nicotine and after use of e-cigarette with nicotine

+1 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Baseline, post e-cigarette without nicotine and post e-cigarette with nicotineExperimental Treatment5 Interventions

Pattern visual event-related potential (ERP) and pattern electroretinogram (pERG) on right eye (non-dilated pupil), followed by eye fundus tissue oximetry on left eye (dilated pupil), followed by optical coherence tomography angiography (OCT-A) on left eye (dilated pupil).

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Electronic cigarette without nicotine

2022

N/A

~50

RETI-port/scan 21

2022

N/A

~50

Zilia Ocular

2022

N/A

~50

OCT-A

2019

N/A

~80

Electronic cigarette with nicotine

2022

N/A

~50

Do I qualify?Apply below to find out

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Who is running the clinical trial?

Christian CasanovaLead Sponsor

Christian Casanova, PhDPrincipal InvestigatorÉcole d'optométrie de l'Université de Montréal

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What criteria must be fulfilled to participate in this research endeavor?

"This clinical trial is seeking 44 participants who are between 18 and 40 years old, and have a history of vaping."

Answered by AI

How many participants are partaking in this experiment?

"Affirmative. The clinical trial in question, which was first announced on August 25th 2022, is currently enrolling participants as per the information found on clinicaltrials.gov. 44 patients need to be recruited at a single medical centre."

Answered by AI

Does this trial permit adults as participants?

"The parameters for this clinical trial allows for individuals aged 18-40 to join. For those outside of the age range, there is an additional 2 trials available for minors and 4 studies accessible to seniors over 65."

Answered by AI

Is there still availability for enrolment in this research project?

"Affirmative. Clinicaltrials.gov data affirms that this medical experiment is actively looking for participants, beginning on August 25th 2022 and most recently updated April 3rd 2023. This clinical trial aims to recruit 44 individuals from one site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Nicotine Influence on the Retina Following the Use of Electronic Cigarette

Christian Casanova 2022. "Nicotine Influence on the Retina Following the Use of Electronic Cigarette". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05801419.