This trial is evaluating whether Treatment will improve 1 primary outcome, 8 secondary outcomes, and 4 other outcomes in patients with Pediatric Obesity. Measurement will happen over the course of 4 months [0 - 4 month].
This trial requires 420 total participants across 2 different treatment groups
This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"The signs and symptoms of obesity vary significantly from individual to individual depending on body weight. A careful physical examination is essential in the evaluation of obesity and the detection of obesity-related diseases, and the clinician can consider all" - Anonymous Online Contributor
"Results from a recent clinical trial provides the estimates of the annual numbers of youth who are obese, and can be used for policy-oriented and political discussions with the federal departments of health and the federal agencies involved in the education and health promotion of youth. In order to maximize the prevention of obesity among youth, we need to work on this epidemic issue." - Anonymous Online Contributor
"Obesity is a condition in which an individual has an elevated body mass index (BMI) value compared to the World Health Organisation (2000) reference criteria. It increases the risk of obesity-associated illnesses such as diabetes mellitus and cancer of the colon, liver and pancreatic islets. More than half of all obese individuals are unaware or cannot correctly attribute their weight to their excessive eating of food items exceeding recommendations." - Anonymous Online Contributor
"Genetic factors play a significant role in obesity. Obesity is also due to behavioral factors in which people eat large amounts of fast-fat foods that are high in carbohydrates and simple sugars. Behavioral factors can be minimized with the use of dieters and exercise. However, these factors can be exacerbated in genetically predisposed individuals by stress hormones, stress, smoking, alcohol abuse, sleep disturbances, obesity or other health issues, and exposure to pesticides or pollutants in our environment." - Anonymous Online Contributor
"Obesity may be treated with diet and exercise, diet alone or bariatric surgery. Weight loss after bariatric surgery is not common despite many patients being in a'satisfied' weight range." - Anonymous Online Contributor
"Findings from a recent study demonstrates that weight loss is not only more effective than a placebo, it is more effective with prescription medicines. Most of our patients achieved a 5-10 % weight loss. Patients with a BMI in the obese range who are able to achieve a weight loss over 5–10% are likely to persist in a weight loss program, and thus achieve a greater long-term weight reduction and lower blood pressure. This suggests that treatment can be more effective than a placebo since more patients would likely be able to achieve an actual weight loss." - Anonymous Online Contributor
"Results from a recent paper of this open-label trial suggest that further placebo-controlled randomized clinical trials of pioglitazone (a sulfonylurea) in overweight and obese individuals with type 2 diabetes were warranted." - Anonymous Online Contributor
"Obesity continues to be an issue in the family. The majority of children in the series were overweight, and many were obese. It is important for parents to be aware that obesity in one family member can make obesity more challenging within the family and more likely to develop in the children." - Anonymous Online Contributor
"Obesity rises rapidly in young adulthood, from 20 years of age onwards, but not until one looks at the age-expectancy pattern. The reason for this can be found in the timing of the onset of the most dangerous risk factors (smoking and sedentariness) in different age groups. The prevalence of overweight and obesity has been associated with a number of personal and environmental risk factors such as socioeconomic status, schooling, and family socio-ecological environment." - Anonymous Online Contributor
"There are several new discoveries that show promising results for overcoming obesity. A new avenue for research could be the use of anti-obesity drugs, which inhibit the PPARγ/γ-activated signalling or induce the SIRT/LKB1-activated signalling, two important signalling systems for counteracting the effects of PPARγ and SREBP. Another avenue for research could be the use of GPR40 analogues; a receptor, that in obese patients was shown to stimulate food intake and adipose tissue growth. This type of drug might lead to new treatments for obesity." - Anonymous Online Contributor