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Probiotic

Probiotic Oral Tablets for Oral Hygiene

N/A

Waitlist Available

Led By Whasun O Chung, PhD

Research Sponsored by Oragenics, Inc.

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 weeks

Awards & highlights

Study Summary

This trial will test if taking a probiotic pill every day for 12 weeks can reduce the amount of harmful bacteria in the mouths of healthy young adults, which could help prevent tooth decay and gum disease.

Who is the study for?

This trial is for dentally healthy young adults with a good general health status. Participants must be willing to use birth control, have measurable levels of certain oral bacteria, and possess at least 20 teeth with minimal fillings. Those undergoing cancer treatment, needing antibiotics for dental work, pregnant or planning pregnancy, or suffering from chronic illnesses like heart disease or diabetes cannot join.Check my eligibility

What is being tested?

The study tests if taking ProBiora3 mints daily for twelve weeks can reduce harmful oral bacteria linked to tooth decay and gum disease compared to a placebo tablet in a controlled environment.See study design

What are the potential side effects?

While the trial primarily involves probiotics that are generally considered safe, potential side effects may include digestive discomfort such as bloating or gas due to changes in the balance of oral and gut bacteria.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Enumeration of S. mutans in saliva and seven periodontal pathogens in subgingival plaque

Secondary outcome measures

Breath odor

Teeth whiteness

Trial Design

2Treatment groups

Active Control

Placebo Group

Group I: Probiotic tabletActive Control1 Intervention

Group II: Placebo tabletPlacebo Group1 Intervention

Comparison tablet without the probiotic bacteria

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Oragenics, Inc.Lead Sponsor

1 Previous Clinical Trials

200 Total Patients Enrolled

University of WashingtonOTHER

1,738 Previous Clinical Trials

1,844,303 Total Patients Enrolled

Whasun O Chung, PhDPrincipal InvestigatorUniversity of Washington

Media Library

ProBiora3 (Probiotic) Clinical Trial Eligibility Overview. Trial Name: NCT01520974 — N/A

Oral Hygiene Research Study Groups: Placebo tablet, Probiotic tablet

Oral Hygiene Clinical Trial 2023: ProBiora3 Highlights & Side Effects. Trial Name: NCT01520974 — N/A

ProBiora3 (Probiotic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01520974 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible for new participants to enroll in this research?

"According to the details on clinicaltrials.gov, this medical study is not currently recruiting participants. It was initially posted in January 2012 and last updated in May of the same year. Nonetheless, there are 10 other trials actively seeking volunteers at present."

Answered by AI

Is this clinical research recruiting individuals aged 45 or older?

"As per the study's regulations, only individuals aged between 18 and 35 are eligible to join this clinical trial."

Answered by AI

Are there any eligibility requirements for participation in this clinical experiment?

"This clinical trial is currently accepting 48 people who meet the following criteria: aged between 18 and 35, measurable levels of Streptococcus mutans in their system and one or more periodontal pathogens, possessing at least 20 teeth with minimal fillings, and willing to use contraception while participating."

Answered by AI