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Behavioural Intervention

Cerebellar transcranial direct current stimulation at 4 mA for Parkinson's Disease

N/A
Waitlist Available
Led By Craig D Workman, PhD
Research Sponsored by University of Iowa
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, up to 12 months
Awards & highlights

Study Summary

Multiple Sessions of Transcranial Direct Current Stimulation in People With Parkinson's Disease

Eligible Conditions
  • Parkinson's Disease
  • Healthy Adults

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, up to 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, up to 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
30-meter walk test, dual-task (30mWT-DT; 2 trials)
30-meter walk test, single-task (30mWT-ST; 2 trials)
6-minute walk test (6MWT; 1 trial)
+9 more
Secondary outcome measures
Brain activity PET Imaging with [18F]Fluorodeoxyglucose (FDG)

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: PD-ctDCSExperimental Treatment1 Intervention
People with Parkinson's disease will have both electrodes placed 1-2 cm below and 3 cm to either side of the inion, with the anode assigned to the most PD-affected side and the cathode assigned to the less PD-affected side. Stimulation is ramped up to 4 mA over the first 30 seconds and stays at 4 mA for the remainder of the stimulation time.
Group II: NH-ctDCSActive Control1 Intervention
Neurologically healthy older adults will have both electrodes placed 1-2 cm below and 3 cm to either side of the inion, with the anode assigned to the most PD-affected side and the cathode assigned to the non-dominant side. Stimulation is ramped up to 4 mA over the first 30 seconds and stays at 4 mA for the remainder of the stimulation time.
Group III: PD-shamPlacebo Group1 Intervention
People with Parkinson's disease will have both electrodes placed 1-2 cm below and 3 cm to either side of the inion, with the anode assigned to the most PD-affected side and the cathode assigned to the less PD-affected side. Stimulation is turned on (4 mA) for 30 seconds at the beginning and the end of the trial, but it turned to 0 mA in the intervening time.
Group IV: NH-shamPlacebo Group1 Intervention
Neurologically healthy older adults will have both electrodes placed 1-2 cm below and 3 cm to either side of the inion, with the anode assigned to the most PD-affected side and the cathode assigned to the non-dominant side. Stimulation is turned on (4 mA) for 30 seconds at the beginning and the end of the trial, but it turned to 0 mA in the intervening time.

Find a Location

Who is running the clinical trial?

University of IowaLead Sponsor
447 Previous Clinical Trials
879,722 Total Patients Enrolled
Craig D Workman, PhDPrincipal InvestigatorUniversity of Iowa
2 Previous Clinical Trials
42 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Multiple Sessions of Transcranial Direct Current Stimulation in People With Parkinson's Disease
Craig D. Workman, PhD 2021. "Multiple Sessions of Transcranial Direct Current Stimulation in People With Parkinson's Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04762823.
~0 spots leftby Apr 2025
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