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Psychological Treatments for Obsessive-Compulsive Disorder

N/A
Recruiting
Led By Adam S Radomsky, PhD
Research Sponsored by Concordia University, Montreal
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of OCD
Be older than 18 years old
Must not have
Participants on medication must be on a stable dose (i.e. have maintained a consistent dose for at least three months) and agree not to change their medication regimen for the duration of the study
Diagnosis of bipolar disorder (I or II)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion (week 3; week 6; one week post therapy; 6 month follow-up; 12 month follow-up).
Awards & highlights

Summary

This trial will compare a traditional behavioral approach to OCD with a newer cognitive-based approach to see which is more effective and more acceptable to patients.

Who is the study for?
This trial is for English-speaking individuals diagnosed with OCD who are not currently experiencing psychosis, suicidal thoughts, bipolar disorder, or substance abuse. Participants on medication must have been on a stable dose for at least three months and agree to keep it unchanged during the study.Check my eligibility
What is being tested?
The study compares traditional Exposure and Response Prevention (ERP) therapy with a newer cognitive approach for treating OCD. The goal is to see if the cognitive method reduces symptoms as effectively as ERP while being more acceptable and having lower dropout rates.See study design
What are the potential side effects?
While there may not be direct side effects from these psychological treatments, participants might experience increased anxiety or distress initially when facing their fears in ERP or engaging in challenging cognitive exercises.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have been diagnosed with OCD.

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
Select...
I have been on the same dose of my medication for at least three months and agree not to change it during the study.
Select...
I have been diagnosed with bipolar disorder.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion (week 3; week 6; one week post therapy; 6 month follow-up; 12 month follow-up).
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion (week 3; week 6; one week post therapy; 6 month follow-up; 12 month follow-up). for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Incidents of participants that drop-out of treatment
Incidents of participants that refuse treatment
Treatment and Acceptability Adherence Scale (TAAS; Milosevic, Levy, Alcolado & Radomsky, 2015)
Secondary outcome measures
Anxiety Disorders Interview Schedule for DSM-5 (ADIS-5; Brown & Barlow, 2014)
The Vancouver Obsessional Compulsive Inventory (VOCI; Thordarson, Radomsky, Rachman, et al., 2004)
The Yale-Brown Obsessive Compulsive Scale (YBOCS; Goodman, Price, Rasmussen, et al., 1989)

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Cognitive TherapyExperimental Treatment1 Intervention
A modularized, cognitive-behavioural therapy intervention that incorporates evidence gathering and behavioural experiments. Our CT protocols rely heavily on behavioural experiments which are typically targeted and brief exercises designed to permit clients/patients to gather disconfirmatory evidence about their beliefs.
Group II: Behavioural TherapyActive Control1 Intervention
Method of behavioral therapy and form of exposure and response prevention therapy in which individuals confront their fears and discontinue their escape response. Exposures in this protocol are prolonged and repeated, requiring clients/patients to engage in a series of exposures to feared stimuli (e.g., contaminants, doubts, intrusive thoughts), and to refrain from engaging in compulsive behaviour until their anxiety subsides.

Find a Location

Who is running the clinical trial?

University College London HospitalsOTHER
194 Previous Clinical Trials
1,171,502 Total Patients Enrolled
McGill UniversityOTHER
400 Previous Clinical Trials
1,000,094 Total Patients Enrolled
University of British ColumbiaOTHER
1,431 Previous Clinical Trials
2,478,803 Total Patients Enrolled
6 Trials studying Obsessive-Compulsive Disorder
733 Patients Enrolled for Obsessive-Compulsive Disorder

Media Library

Cognitive therapy Clinical Trial Eligibility Overview. Trial Name: NCT03661905 — N/A
Obsessive-Compulsive Disorder Research Study Groups: Cognitive Therapy, Behavioural Therapy
Obsessive-Compulsive Disorder Clinical Trial 2023: Cognitive therapy Highlights & Side Effects. Trial Name: NCT03661905 — N/A
Cognitive therapy 2023 Treatment Timeline for Medical Study. Trial Name: NCT03661905 — N/A
~15 spots leftby Jul 2025
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