Neuroblastoma Clinical Trials 2022

Browse 109 Neuroblastoma Medical Studies Across 164 Cities
6 Phase 3 Trial · 2383 Neuroblastoma Clinics

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Clinical Trials Neuroblastoma Clinical Trials 2022

Reviewed by Michael Gill, B. Sc.

Image of Childrens Hospital Los Angeles in Los Angeles, United States.

Phase-Based Progress Estimates

Dinutuximab With Chemotherapyfor Neuroblastoma

Waitlist Available

This trial is testing whether the anti-GD2 human-mouse chimeric monoclonal antibody dinutuximab can be given to children with high-risk neuroblastoma over four hours or less, which would allow for administration of this immunotherapy agent in the outpatient setting.

Waitlist Available

Childrens Hospital Los AngelesUnited Therapeutics

Image of Nationwide Children's Hospital in Columbus, United States.

Phase-Based Progress Estimates

Cabozantinibfor Neuroblastoma

FDA Approved Drug

This trial will study whether the use of cabozantinib can prevent or slow the recurrent formation of pediatric solid tumors.

FDA Approved Drug

Nationwide Children's HospitalNilay Shah, MDExelixis

Image of Memorial Sloan Kettering Cancer Center in New York, United States.

Phase-Based Progress Estimates

Β-glucanfor Neuroblastoma

This trial is testing a combination of three things - a vaccine, a sugar, and a protein - to see if it can effectively treat high-risk neuroblastoma in people who are in complete remission.

Memorial Sloan Kettering Cancer CenterBrian Kushner, MD

Image of Arkansas Children's Hospital in Little Rock, United States.

Phase-Based Progress Estimates

Temozolomidefor High Risk Neuroblastoma

Waitlist Available

FDA Approved Drug

This trial is testing a new chemo-immunotherapy treatment for high-risk neuroblastoma patients who have not experienced worsening or recurrence of their disease after Consolidation therapy.

Waitlist Available

FDA Approved Drug

Arkansas Children's Hospital (+69 Sites)Ami V Desai

Image of Cincinnati Children's Hospital Medical Center in Cincinnati, United States.

Phase-Based Progress Estimates

VAL-413for Rhabdomyosarcoma

FDA Approved Drug

This trial is testing a flavored, orally-administered form of irinotecan (VAL-413) given with temozolomide to see if it is safe and effective for treating recurrent pediatric solid tumors, including neuroblastoma, rhabdomyosarcoma, Ewing sarcoma, hepatoblastoma and medulloblastoma.

FDA Approved Drug

Cincinnati Children's Hospital Medical Center (+1 Sites)Lars Wagner, M.D.Valent Technologies, Inc.

Image of New York Medical College in Valhalla, United States.

Phase-Based Progress Estimates

Vorinostatfor Hepatoblastoma

FDA Approved Drug

This trial is testing a new experimental drug combination in the hopes of finding a more effective treatment against tumors.

FDA Approved Drug

New York Medical CollegeJeremy Rosenblum, MD

Image of Boston Children's Hospital in Boston, United States.

Phase-Based Progress Estimates

GVAX Vaccinefor Neuroblastoma

FDA Approved Drug

This trial is studying how well GVAX, given in combination with nivolumab and ipilimumab, works in treating patients with neuroblastoma.

FDA Approved Drug

Boston Children's Hospital (+1 Sites)Natalie B Collins, MD, PHD

Image of Childrens Hospital of Los Angeles in Los Angeles, United States.

Phase-Based Progress Estimates

LY3295668 Erbuminefor Neuroblastoma

Waitlist Available

FDA Approved Drug

This trial is testing a new drug to see if it is safe for people with neuroblastoma that has come back or does not respond to treatment.

Waitlist Available

FDA Approved Drug

Childrens Hospital of Los Angeles (+15 Sites)Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)Eli Lilly and Company

Image of Phoenix Children's Hospital in Phoenix, United States.

Phase-Based Progress Estimates

Idasanutlinfor Neuroblastoma

FDA Approved Drug

This trial is studying idasanutlin, given alone or with other drugs, as a possible treatment for pediatric and young adult participants with solid tumors or leukemias.

FDA Approved Drug

Phoenix Children's Hospital (+9 Sites)Clinical TrialsHoffmann-La Roche

Image of St. Jude Children's Research Hospital in Memphis, United States.

Phase-Based Progress Estimates

18F-DAfor Neuroblastoma

This trial will use PET scans combined with a radioactive tracer (18F-DA) to examine neuroblastoma tumors. The goal is to see if this tracer is safe and more effective than the current standard (123I-mIBG).

St. Jude Children's Research HospitalBarry Shulkin, MD

Image of Lucile Packard Children's Hospital in Palo Alto, United States.

Phase-Based Progress Estimates

CLR 131for Neuroblastoma

This trial is testing a new cancer treatment called CLR 131 in children, adolescents, and young adults with cancer that has come back or didn't respond to initial treatment and for which there are no standard treatment options.

Lucile Packard Children's Hospital (+5 Sites)John Friend, MDCellectar Biosciences, Inc.

Image of Children's Hospital Los Angeles in Los Angeles, United States.

Phase-Based Progress Estimates

131I-MIBGfor Neuroblastoma

FDA Approved Drug

This trial is testing a new therapy for neuroblastoma, which is a cancer that primarily affects children. The therapy is a combination of two drugs, and the goal of the trial is to determine the best dose of the two drugs to give to patients. If the therapy is well tolerated, a third drug will be added to the trial.

FDA Approved Drug

Children's Hospital Los Angeles (+10 Sites)Araz Marachelian, MD, MSUnited Therapeutics

Image of Texas Children's Hospital in Houston, United States.

Phase-Based Progress Estimates

GINAKIT Cellsfor Neuroblastoma

FDA Approved Drug

This trial is testing a new way to fight cancer that combines two existing methods: antibodies and Natural Killer T cells. Antibodies are proteins that protect the body, and T cells are white blood cells that can kill other cells, including cancer cells. The new method being tested, called GD2-CAR, is designed to improve upon previous methods by specifically targeting neuroblastoma cells and by adding a gene segment to make the NKT cells last longer.

FDA Approved Drug

Texas Children's HospitalAndras Heczey, MD

Image of University of Iowa Hospitals and Clinics in Iowa City, United States.

Phase-Based Progress Estimates

90Y-DOTA-tyr3-Octreotidefor Neuroblastoma

Waitlist Available

FDA Approved Drug

This trial is testing a new cancer treatment that involves using a radioactive substance to target and kill cancer cells.

Waitlist Available

FDA Approved Drug

University of Iowa Hospitals and ClinicsM. Sue O'Dorisio, MD, PhD

Image of Children's Hospital of Alabama in Birmingham, United States.

Phase-Based Progress Estimates

Autologous Hematopoietic Stem Cell Transplantationfor Ganglioneuroblastoma

FDA Approved Drug

This trial is testing a new drug, lorlatinib, in combination with the standard treatment for neuroblastoma or ganglioneuroblastoma, compared to the standard treatment alone.

FDA Approved Drug

Children's Hospital of Alabama (+99 Sites)Steven DuBois

Image of University of Wisconsin Carbone Cancer Center; UW Hospital and Clinics; American Family Children's Hospital in Madison, United States.

Phase-Based Progress Estimates

Nivolumabfor Neuroblastoma

FDA Approved Drug

FDA Approved Drug

University of Wisconsin Carbone Cancer Center; UW Hospital and Clinics; American Family Children's HospitalJuliet Gray

Image of Memorial Sloan Kettering Cancer Center in New York, United States.

Phase-Based Progress Estimates

External Beam Radiotherapyfor Neuroblastoma

This trial is testing a lower dose of radiation to see if it decreases side effects experienced years after treatment.

Memorial Sloan Kettering Cancer CenterSuzanne Wolden, MD

Image of Arkansas Children's Hospital in Little Rock, United States.

Phase-Based Progress Estimates

Guided Therapyfor Clear Cell Sarcoma of Soft Tissue

Waitlist Available

This trial is testing if new technology that decodes a tumor's DNA can help docs better understand cancer & predict treatment.

Waitlist Available

Arkansas Children's Hospital (+17 Sites)Giselle Sholler, MDDell, Inc.

Image of Massachusetts General Hospital in Boston, United States.

Phase-Based Progress Estimates

Proton Beam Radiation Therapyfor Neuroblastoma

This trial is looking at proton beam radiation therapy (PBRT) as a possible treatment for neuroblastoma. Neuroblastoma is a cancer that most commonly occurs in and around the adrenal glands, but can also occur in other areas where groups of nerve cells exist. Standard radiation therapy with photons is used as standard treatment for many patients with neuroblastic tumors, but proton radiation is known to spare surrounding tissues and organs from unnecessary radiation. The trial will assess the effectiveness of PBRT in reducing side effects associated with radiation treatment and the late side effects experienced by participants.

Massachusetts General HospitalShannon M. MacDonald, MD

Image of Houston Methodist Hospital in Houston, United States.

Phase-Based Progress Estimates

IC9-GD2 T Cellsfor Neuroblastoma

Waitlist Available

FDA Approved Drug

This trial is for people with relapsed or refractory neuroblastoma who will receive iC9-GD2 T cells after lymphodepletion with fludarabine and cyclophosphamide.

Waitlist Available

FDA Approved Drug

Houston Methodist Hospital (+1 Sites)Andras A. Heczey, MD

Image of Memorial Sloan Kettering Cancer Center in New York, United States.

Phase-Based Progress Estimates

Humanized 3F8 Monoclonal Antibody (Hu3F8)for Neuroblastoma

Waitlist Available

FDA Approved Drug

This trial is testing an experimental drug, Hu3F8, to see if it is safe and effective in treating neuroblastoma and other cancers.

Waitlist Available

FDA Approved Drug

Memorial Sloan Kettering Cancer CenterEllen Basu, MD,PhDY-mAbs Therapeutics

Image of Texas Children's Hospital in Houston, United States.

Phase-Based Progress Estimates

Neuroblastoma Vaccine (unmodified SKNLP, With Gene-modified SJNB-JF-IL2 And SJNB-JF-LTN Neuroblastoma Cellsfor Neuroblastoma

Waitlist Available

FDA Approved Drug

This trial is testing an experimental treatment for neuroblastoma, which is a solid tumor that is the second most common cancer in children. The treatment consists of a series of immunizations using a tumor vaccine, combined with low-dose chemotherapy taken by mouth on a daily basis. The hope is that the vaccine will cause the immune system to recognize and kill more types of neuroblastoma tumors. Additionally, the immunizations will be combined with daily low dose chemotherapy.

Waitlist Available

FDA Approved Drug

Texas Children's HospitalAndras A. Heczey, MD

Image of St. Jude Children's Research Hospital in Memphis, United States.

Phase-Based Progress Estimates

Methioninefor Neuroblastoma

FDA Approved Drug

This trial is testing the usefulness of imaging with radiolabeled methionine to find tumors in children and young adults.

FDA Approved Drug

St. Jude Children's Research HospitalBarry L Shulkin, MD

Image of Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center in Hershey, United States.

Phase-Based Progress Estimates

Cyclophosphamidefor Leukemia

Waitlist Available

FDA Approved Drug

This trial is studying whether using stem cells from umbilical cord blood can help treat cancer or other diseases.

Waitlist Available

FDA Approved Drug

Penn State Hershey Cancer Institute at Milton S. Hershey Medical CenterKenneth G. Lucas, MD

Image of Children's Wisconsin in Milwaukee, United States.

Phase-Based Progress Estimates

Anti-CD30 Bispecific Antibody-armed Anti-CD3-Activated Autologous T-cells (CD30 BiAb-AATC)for CD30+ Anaplastic Large Cell Lymphoma

Waitlist Available

This trial will see if a new immunotherapy is safe and effective. It uses a patient's own T-cells that are armed with a CD30 antibody.

Waitlist Available

Children's WisconsinNathan Schloemer, MD

25 Neuroblastoma Clinical Trials Near Me

Top Hospitals for Neuroblastoma Clinical Trials

Image of Children's Hospital Los Angeles in California.

Children's Hospital Los Angeles

Los Angeles

29Active Trials

74All Time Trials for Neuroblastoma

1988First Neuroblastoma Trial

Image of Children's Hospital Colorado in Colorado.

Children's Hospital Colorado

Aurora

28Active Trials

47All Time Trials for Neuroblastoma

2000First Neuroblastoma Trial

Top Cities for Neuroblastoma Clinical Trials

Image of Saint Louis in Missouri.

Saint Louis

61Active Trials

Washington University School of MedicineTop Active Site

Image of New York in New York.

New York

59Active Trials

Memorial Sloan Kettering Cancer CenterTop Active Site

Neuroblastoma Clinical Trials by Phase of Trial

Phase < 1 Neuroblastoma Clinical Trials

4Active Neuroblastoma Clinical Trials

4Number of Unique Treatments

4Number of Active Locations

18F-DA Gallium Ga 68-DOTATATE Cyclophosphamide Hu3F8