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Neuroblastoma Clinical Trials
Neuroblastoma studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect neuroblastoma clinical trial.
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Cryoablation Therapy
Washington, United States
< 65
All Sexes
Phase 2
Recruiting
Metastatic
Washington, United States
< 65
All Sexes
The is a phase II, single arm, open-label, multi-site trial studying the combination of cryoablation therapy and dual checkpoint inhibition with nivolumab (anti-PD-1) and ipilimumab (anti-CTLA-4) given at the recommended phase 2 dose (RP2D) in pediatric and young adult patients with relaps…
Cabozantinib
Columbus, OH
< 65
All Sexes
Phase 2
Recruiting
Grade I
Columbus, OH
< 65
All Sexes
This study will expand the types of pediatric cancers being evaluated for response to cabozantinib. The current COG study is restricted to Ewing sarcoma, osteosarcoma, rhabdomyosarcoma, Wilms tumor, and a handful of uncommon tumors. The proposed study will extend this evaluation to tumors …
Bintrafusp alfa / M7824
Bethesda, MD
18+
All Sexes
Phase 2
Recruiting
Locally Advanced
Bethesda, MD
18+
All Sexes
This study is evaluating whether a drug can shrink or disappear ONB tumors.
Cyclophosphamide
New York, NY
< 18
All Sexes
Phase < 1
Recruiting
Metastatic
New York, NY
< 18
All Sexes
This study is evaluating whether a drug called N9 is safe and effective for children with neuroblastoma.
β-glucan
New York, NY
Any Age
All Sexes
Phase 2
Recruiting
Grade III
New York, NY
Any Age
All Sexes
This study is evaluating whether a combination of a vaccine, a sugar, and a protein can be effective in treating people with high-risk neuroblastoma.
Tegavivint
Boston, MA
< 65
All Sexes
Phase 1 & 2
Recruiting
Metastatic
Boston, MA
< 65
All Sexes
This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come back (recurrent) or does not respond to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, whic…
Tumor-specific ex vivo expanded autologous lymphocyte transfer (TTRNA-xALT)
Gainesville, FL
< 65
All Sexes
Phase 1
Recruiting
High Risk
Gainesville, FL
< 65
All Sexes
This study is evaluating whether a combination of treatments may help children with DIPG or recurrent neuroblastoma.
Magrolimab
Vancouver, Canada
< 65
All Sexes
Phase 1
Recruiting
Class II
Vancouver, Canada
< 65
All Sexes
This study is evaluating whether a combination of two monoclonal antibodies can shrink or stabilize relapsed or refractory neuroblastoma or relapsed osteosarcoma.
Nivolumab
Bronx, NY
< 65
All Sexes
Phase 1 & 2
Recruiting
1 Prior Treatment
Bronx, NY
< 65
All Sexes
This study is evaluating whether a combination of two drugs may help treat children and young adults with cancer.
18F-MFBG
New York, NY
Any Age
All Sexes
Phase 3
Recruiting
New York, NY
Any Age
All Sexes
This study is evaluating whether a PET scan can be used to confirm or exclude the presence of neuroblastoma.
18F-DOPA
Edmonton, Canada
Any Age
All Sexes
Phase 3
Recruiting
Metastatic
Edmonton, Canada
Any Age
All Sexes
This study is evaluating whether a PET scan can be used to help diagnose neuroendocrine tumors in children and adults.
Radiopharmaceutical 68Ga-DOTATATE
Montréal, Canada
< 65
All Sexes
Phase 2
Recruiting
Montréal, Canada
< 65
All Sexes
This study is evaluating whether a new imaging agent can be used to stage neuroblastoma.
GD2-CAR-expressing Autologous T-lymphocytes
Madison, WI
< 65
All Sexes
Phase 1
Recruiting
Grade I
Madison, WI
< 65
All Sexes
This study is evaluating whether a new type of immune cell therapy called GD2CART is safe and effective in treating patients with osteosarcoma or neuroblastoma that has come back (relapsed) or does not respond to treatment (refractory).
Allogeneic Hematopoietic Stem Cell Transplantation
Houston, TX
< 65
All Sexes
Phase 2
Recruiting
Class I
Houston, TX
< 65
All Sexes
This study is evaluating whether a stem cell transplant may help treat cancer that has come back or does not respond to treatment.
Nivolumab
Houston, TX
< 65
All Sexes
Phase 1
Recruiting
Metastatic
Houston, TX
< 65
All Sexes
This study is evaluating whether the combination of two immunotherapy drugs may help treat children and adolescents with cancer.
second generation 4-1BBζ B7H3-EGFRt-DHFR(selected) and a second generation 4-1BBζ CD19-Her2tG
Seattle, WA
< 65
All Sexes
Phase 1
Recruiting
1 Prior Treatment
Seattle, WA
< 65
All Sexes
This study is evaluating whether genetically modified T cells may be able to
Temozolomide
Chicago, IL
< 65
All Sexes
Phase 2
Recruiting
Grade II
Chicago, IL
< 65
All Sexes
This study is evaluating whether a combination of drugs may help treat high-risk neuroblastoma.
Temozolomide
Cincinnati, OH
< 65
All Sexes
Phase 1
Recruiting
Metastatic
Cincinnati, OH
< 65
All Sexes
This study is evaluating whether a new drug may help treat children with cancer.
Selpercatinib
Iowa City, IA
< 65
All Sexes
Phase 2
Recruiting
Locally Advanced
Iowa City, IA
< 65
All Sexes
This study is evaluating whether a drug may help treat certain types of cancer.
Vorinostat
Valhalla, NY
< 65
All Sexes
Phase 1
Recruiting
Metastatic
Valhalla, NY
< 65
All Sexes
Investigators are testing new experimental drug combinations such as the combination of vorinostat, vincristine, irinotecan, and temozolomide in the hopes of finding a drug that may be effective against tumors that have come back or that have not responded to standard therapy. The goals o…
Eflornithine
Charlotte, NC
< 65
All Sexes
Phase 2
Recruiting
Metastatic
Charlotte, NC
< 65
All Sexes
This study is evaluating whether a drug called DFMO may help treat neuroblastoma.
Tipifarnib
Cleveland, OH
< 65
All Sexes
Phase 2
Recruiting
Grade II
Cleveland, OH
< 65
All Sexes
This study is evaluating whether a drug called tipifarnib may help treat children with cancer.
9-ING-41
Durham, NC
< 65
All Sexes
Phase 1
Recruiting
Locally Advanced
Durham, NC
< 65
All Sexes
This study is evaluating whether a drug called 9-ING-41 may help treat cancer in children.
GVAX vaccine
Boston, MA
Any Age
All Sexes
Phase 1
Recruiting
Grade II
Boston, MA
Any Age
All Sexes
This research clinical trial is studying the creation and administration of GVAX, an irradiated GM-CSF secreting, autologous neuroblastoma cell vaccine (GVAX) in combination with nivolumab and ipilimumab as a possible treatment for neuroblastoma. The names of the study drugs involved in t…
Ivosidenib
New York, NY
< 65
All Sexes
Phase 2
Recruiting
Grade II
New York, NY
< 65
All Sexes
This study is evaluating whether a drug may help treat children with cancer.
LY3295668 Erbumine
Atlanta, GA
< 65
All Sexes
Phase 1
1 Prior Treatment
Atlanta, GA
< 65
All Sexes
This study is evaluating whether a drug may help treat neuroblastoma.
Gallium Ga 68-DOTATATE
Rochester, MN
< 65
All Sexes
Phase < 1
Recruiting
Metastatic
Rochester, MN
< 65
All Sexes
This study is evaluating whether a new type of scan called a PET/CT scan can help diagnose neuroendocrine tumors in children.
Idasanutlin
Palo Alto, CA
< 65
All Sexes
Phase 1 & 2
Recruiting
1 Prior Treatment
Palo Alto, CA
< 65
All Sexes
This is a Phase I/II, multicenter, open-label, multi-arm study designed to evaluate the safety, tolerability, pharmacokinetics, and preliminary efficacy of idasanutlin, administered as a single agent or in combination with chemotherapy or venetoclax, in pediatric and young adult participan…
67Cu-SARTATE
Cincinnati, OH
Any Age
All Sexes
Phase 1 & 2
Recruiting
1 Prior Treatment
Cincinnati, OH
Any Age
All Sexes
This study is evaluating whether a radioactive substance may help treat neuroblastoma.
dabrafenib
Washington, United States
Any Age
All Sexes
Phase 4
Recruiting
Washington, United States
Any Age
All Sexes
This study is evaluating whether a combination of two drugs may help children with cancer.
Humanized 3F8 Bispecific Antibody
New York, NY
< 18
All Sexes
Phase 1 & 2
Recruiting
Stage III
New York, NY
< 18
All Sexes
This study is evaluating whether a new drug may be safe for individuals with cancer.
Eflornithine Hydrochloride
Orlando, FL
Any Age
All Sexes
Phase 2
Recruiting
Grade II
Orlando, FL
Any Age
All Sexes
This study is evaluating whether a combination of chemotherapy, immunotherapy, and eflornithine might be more effective than chemotherapy alone in treating patients with relapsed or refractory neuroblastoma.
Cyclophosphamide
Salt Lake City, UT
< 65
All Sexes
Phase 2
High Risk
Salt Lake City, UT
< 65
All Sexes
This study is evaluating the side effects and how well dinutuximab and sargramostim work with combination chemotherapy in patients with high-risk neuroblastoma undergoing stem cell transplant.
iC9.GD2.CAR.IL-15 T-cells
Chapel Hill, NC
< 65
All Sexes
Phase 1
Recruiting
High Risk
Chapel Hill, NC
< 65
All Sexes
The body has different ways of fighting infections and disease. No single way seems perfect for fighting cancer. This research study combines two different ways of fighting disease: antibodies and T cells. Antibodies are molecules that fight infections and protect your body from diseases c…
Palbociclib
Louisville, KY
< 65
All Sexes
Phase 2
Recruiting
Grade I
Louisville, KY
< 65
All Sexes
This study is evaluating whether a drug may help children with cancer.
Ulixertinib
Atlanta, GA
< 65
All Sexes
Phase 2
Locally Advanced
Atlanta, GA
< 65
All Sexes
This study is evaluating whether ulixertinib is effective in treating children with solid tumors that have spread to other places in the body (advanced), non-Hodgkin lymphoma, or histiocytic disorders that have a genetic
C7R-GD2.CART cells
Houston, TX
Any Age
All Sexes
Phase 1
Recruiting
Locally Advanced
Houston, TX
Any Age
All Sexes
This study is for patients with neuroblastoma, sarcoma, uveal melanoma, breast cancer, or another cancer that expresses a substance on the cancer cells called GD2. The cancer has either come back after treatment or did not respond to treatment. Because there is no standard treatment at thi…
second generation 4-1BBζ EGFR806-EGFRt and a second generation 4 1BBζ CD19-Her2tG
Seattle, WA
< 65
All Sexes
Phase 1
Recruiting
1 Prior Treatment
Seattle, WA
< 65
All Sexes
This is a phase I, open-label, non-randomized study that will enroll pediatric and young adult research participants with relapsed or refractory non-CNS solid tumors to evaluate the safety, feasibility, and efficacy of administering T cell products derived from the research participant's b…
131I-MIBG
San Francisco, CA
Any Age
All Sexes
Phase 2
Recruiting
1 Prior Treatment
San Francisco, CA
Any Age
All Sexes
This study is evaluating whether a radioactive substance may help treat neuroblastoma.
18F-DA
Memphis, TN
Any Age
All Sexes
Phase < 1
Recruiting
1 Prior Treatment
Memphis, TN
Any Age
All Sexes
PET (positron emission tomography) scans combined with a radioactive tracer will be used to identify and analyze tumors. Currently, the most common tracer used to analyze neuroblastoma tumors is called 123I-mIBG. However, the picture it provides is not always clear enough to see the very s…
Palbociclib
Ann Arbor, MI
< 65
All Sexes
Phase 2
Recruiting
Locally Advanced
Ann Arbor, MI
< 65
All Sexes
This study is evaluating whether a drug may help treat children with cancer.
CLR 131
Toronto, Canada
< 65
All Sexes
Phase 1
Recruiting
Metastatic
Toronto, Canada
< 65
All Sexes
This study is evaluating whether a drug called CLR 131 may help treat cancer.
Gemcitabine
Memphis, TN
< 65
All Sexes
Phase 1
Recruiting
Grade II
Memphis, TN
< 65
All Sexes
Approximately 90% of children with malignant brain tumors that have recurred or relapsed after receiving conventional therapy will die of disease. Despite this terrible and frustrating outcome, continued treatment of this population remains fundamental to improving cure rates. Studying thi…
GM-CSF + Naxitamab
Toronto, Canada
Any Age
All Sexes
Phase 2
Recruiting
Toronto, Canada
Any Age
All Sexes
Children and adults diagnosed with high-risk neuroblastoma patients with primary refractory disease or incomplete response to salvage treatment in bone and/or bone marrow will be treated for up to 101 weeks with naxitamab and granulocyte-macrophage colony stimulating factor (GM-CSF). Patie…
131I-MIBG
Boston, MA
< 65
All Sexes
Phase 1
Recruiting
High Risk
Boston, MA
< 65
All Sexes
This study is evaluating whether a combination of two therapies may be more effective than either therapy alone.
GINAKIT Cells
Houston, TX
< 65
All Sexes
Phase 1
Recruiting
High Risk
Houston, TX
< 65
All Sexes
This research study combines two different ways of fighting cancer: antibodies and Natural Killer T cells (NKT). Antibodies are types of proteins that protect the body from infectious diseases and possibly cancer. T cells, also called T lymphocytes, are special white blood cells that can k…
venetoclax
New York, NY
< 65
All Sexes
Phase 1
Recruiting
1 Prior Treatment
New York, NY
< 65
All Sexes
This study is evaluating whether a drug may help treat cancer.
Olaparib
Mineola, NY
< 65
All Sexes
Phase 2
Locally Advanced
Mineola, NY
< 65
All Sexes
This study is evaluating whether olaparib may help treat children with cancer.
Vemurafenib
Tucson, AZ
< 65
All Sexes
Phase 2
Locally Advanced
Tucson, AZ
< 65
All Sexes
This study is evaluating whether a drug may help treat children with cancer.
Larotrectinib Sulfate
New York, NY
< 65
All Sexes
Phase 2
Recruiting
Grade II
New York, NY
< 65
All Sexes
This study is evaluating whether a drug called larotrectinib may help treat children with cancer.
Selumetinib Sulfate
Toledo, OH
< 65
All Sexes
Phase 2
Locally Advanced
Toledo, OH
< 65
All Sexes
This study is evaluating whether selumetinib sulfate is effective in treating children with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with MAPK pathway activation mutations that have spread to other places in
Tazemetostat
Baltimore, MD
< 65
All Sexes
Phase 2
Grade II
Baltimore, MD
< 65
All Sexes
This study is evaluating whether tazemetostat is effective in treating patients with brain tumors, solid tumors, non-Hodgkin lymphoma, or histiocytic disorders that have come back (relapsed) or do not respond to
Ensartinib
Baltimore, MD
< 65
All Sexes
Phase 2
Recruiting
Locally Advanced
Baltimore, MD
< 65
All Sexes
This study is evaluating whether a drug may help treat children with cancer.
Hu3F8
New York, NY
Any Age
All Sexes
Phase < 1
Metastatic
New York, NY
Any Age
All Sexes
This study is evaluating whether a drug called Hu3F8 can be given with chemotherapy drugs and another drug called GM-CSF.
Samotolisib
Indianapolis, IN
< 65
All Sexes
Phase 2
Recruiting
Locally Advanced
Indianapolis, IN
< 65
All Sexes
This study is evaluating whether genetic testing may help doctors plan better treatment for patients with solid tumors or non-Hodgkin lymphomas.
Dexrazoxane Hydrochloride
San Antonio, TX
< 65
All Sexes
Phase 3
Recruiting
High Risk
San Antonio, TX
< 65
All Sexes
This study is evaluating whether a combination of two drugs may be more effective than one drug alone in treating neuroblastoma.
Lorlatinib
Los Angeles, CA
Any Age
All Sexes
Phase 1
Recruiting
Grade I
Los Angeles, CA
Any Age
All Sexes
This study is evaluating whether a drug may help treat neuroblastoma.
Hu3F8
New York, NY
Any Age
All Sexes
Phase 2
Metastatic
New York, NY
Any Age
All Sexes
This study is evaluating whether a drug called Hu3F8 plus GM-CSF can prevent your neuroblastoma from growing.
Nivolumab
Madison, WI
< 65
All Sexes
Phase 1
Recruiting
High Risk
Madison, WI
< 65
All Sexes
Neuroblastoma, the most common extra-cranial solid tumour in children, remains one of the major challenges in paediatric oncology. A promising way to further improve outcome in this disease appears to be the development of adjuvant therapeutic strategies. In this research the anti-GD2 anti…
CUDC-907
Houston, TX
< 65
All Sexes
Phase 1
Recruiting
Grade II
Houston, TX
< 65
All Sexes
This study is evaluating whether a drug may help treat children with cancer.
Labs
Philadelphia, PA
< 65
All Sexes
Phase 1
Recruiting
1 Prior Treatment
Philadelphia, PA
< 65
All Sexes
The purpose of this research study is to match genomic aberrations in tumor cells at time of relapse to rationally designed combinations of molecularly targeted agents. This study will be done in two parts: Part I: Tumor will be accessed at study entry via a biopsy and subjected to deep s…
Difluoromethylornithine (DFMO)
Minneapolis, MN
< 65
All Sexes
Phase 2
Recruiting
High Risk
Minneapolis, MN
< 65
All Sexes
This study is evaluating whether a drug may help prevent recurrence of neuroblastoma.
NK cells
New York, NY
Any Age
All Sexes
Phase 1
Metastatic
New York, NY
Any Age
All Sexes
This study is evaluating whether it is safe and feasible to give the participant cyclophosphamide, natural killer cells, and an antibody called Hu3F8 as a treatment for neuroblastoma.
Abemaciclib
Atlanta, GA
< 65
All Sexes
Phase 1
Recruiting
Grade III
Atlanta, GA
< 65
All Sexes
This study is evaluating whether a drug may help treat brain tumors.
Autologous Stem Cell Infusion
Minneapolis, MN
< 65
All Sexes
Phase 2
Recruiting
Minneapolis, MN
< 65
All Sexes
This study is evaluating whether a specific chemotherapy regimen may help improve survival for individuals with neuroblastoma.
NK Cells
Columbus, OH
< 65
All Sexes
Phase 1
Recruiting
High Risk
Columbus, OH
< 65
All Sexes
This study is evaluating whether a combination of natural killer cells and chemotherapy may help treat children with neuroblastoma.
Magnetic resonance high intensity focused ultrasound
Washington, United States
< 65
All Sexes
Phase 1
Recruiting
1 Prior Treatment
Washington, United States
< 65
All Sexes
This study is evaluating whether a combination of a drug and a focused ultrasound may be effective for treating children with cancer.
Zoledronate
Madison, WI
< 65
All Sexes
Phase 1
Recruiting
Class I
Madison, WI
< 65
All Sexes
This study is evaluating whether a transplant of white blood cells from a close relative may help leukemia patients recover following chemotherapy.
DFMO
Orlando, FL
< 65
All Sexes
Phase 2
High Risk
Orlando, FL
< 65
All Sexes
This study is evaluating whether a new investigational drug can prevent reoccurrence of neuroblastoma that is in remission.
Patient Derived CD171 specific CAR T cells expressing EGFRt (long spacer 2nd generation T cells)
Seattle, WA
< 65
All Sexes
Phase 1
High Risk
Seattle, WA
< 65
All Sexes
This study is evaluating whether genetically modified T cells can help treat neuroblastoma.
124I-Humanized 3F8
New York, NY
Any Age
All Sexes
Metastatic
New York, NY
Any Age
All Sexes
This study is evaluating how an antibody called Hu3F8 travels through the body and to tumors.
Pharmacological Study
Cincinnati, OH
< 65
All Sexes
Phase 1 & 2
Metastatic
Cincinnati, OH
< 65
All Sexes
This study is evaluating whether a combination of nivolumab and ipilimumab is safe and effective in treating younger patients with solid tumors or sarcomas that have come back (recurrent) or do not respond to treatment (refractory).
External beam radiotherapy
New York, NY
< 65
All Sexes
Recruiting
Stage II
New York, NY
< 65
All Sexes
This study is evaluating whether a lower dose of radiation will help reduce late side effects.
Cyclophosphamide
Birmingham, AL
< 18
All Sexes
Phase 3
Recruiting
High Risk
Birmingham, AL
< 18
All Sexes
This study is evaluating whether a treatment plan based on tumor biology may help treat patients with neuroblastoma.
laboratory evaluations of immune responses
Charlottesville, VA
< 65
All Sexes
Phase 1 & 2
Waitlist Available
Charlottesville, VA
< 65
All Sexes
Previous research has demonstrated that investigators can coat (arm) T cells with a special molecule called GD2 bispecific antibody that will help T cells recognize neuroblastoma and osteosarcoma cells and kill them. This bispecific antibody recognizes GD2, a protein found on almost all ne…
Guided Therapy
Charlotte, NC
< 65
All Sexes
High Risk
Charlotte, NC
< 65
All Sexes
This study is evaluating whether a new technology can be used to determine the molecular makeup of a tumor.
Bortezomib
Charleston, SC
< 65
All Sexes
Phase 1 & 2
1 Prior Treatment
Charleston, SC
< 65
All Sexes
This study is evaluating whether a drug called DFMO can be used to treat neuroblastoma.
Proton Beam Radiation Therapy
Boston, MA
< 65
All Sexes
Recruiting
Boston, MA
< 65
All Sexes
This research study is evaluating a therapy called proton beam radiation therapy (PBRT) as a possible treatment for neuroblastoma. Neuroblastoma most commonly occurs in and around the adrenal glands, which are located at the top of the kidneys. However, it can also occur in other areas wh…
Donor NK Cell Infusion
Milwaukee, WI
Any Age
All Sexes
Phase 2
Grade III
Milwaukee, WI
Any Age
All Sexes
This study is evaluating whether a cellular and adoptive immunotherapy approach can improve disease control rate for people with cancer.
Magnetic Resonance High Intensity Focused Ultrasound
Washington, United States
< 65
All Sexes
Phase 1
1 Prior Treatment
Washington, United States
< 65
All Sexes
This study is evaluating whether a new type of surgery may be effective for treating tumors in children and young adults.
DFMO
Philadelphia, PA
< 65
All Sexes
Phase 1
1 Prior Treatment
Philadelphia, PA
< 65
All Sexes
This study is evaluating whether a drug called DFMO can be used with celecoxib, cyclophosphamide and topotecan to treat cancer.
MM-398 (Irinotecan Sucrosofate Liposome Injection) plus cyclophosphamide
Houston, TX
< 65
All Sexes
Phase 1
Recruiting
Locally Advanced
Houston, TX
< 65
All Sexes
This study is evaluating whether a combination of two drugs may help treat certain types of cancer.
GD2 T cells
Houston, TX
Any Age
All Sexes
Phase 1
High Risk
Houston, TX
Any Age
All Sexes
This study is evaluating whether a new gene can be put into T cells that will make them recognize and kill sarcoma and neuroblastoma cells.
radiation therapy
Memphis, TN
< 65
All Sexes
Phase 2
Locally Advanced
Memphis, TN
< 65
All Sexes
This study is evaluating whether a new antibody can improve the outcome of children with high-risk neuroblastoma.
hematopoietic stem cell infusion
Minneapolis, MN
Any Age
All Sexes
Recruiting
Grade I
Minneapolis, MN
Any Age
All Sexes
This study is evaluating whether a radioactive substance may help treat neuroblastoma.
iC9-GD2 T cells
Houston, TX
Any Age
All Sexes
Phase 1
High Risk
Houston, TX
Any Age
All Sexes
This study is evaluating whether a combination of chemotherapy and a gene therapy can improve the survival of patients with relapsed/refractory neuroblastoma.
Guided Therapy- Pediatric Gene Analysis Platform
Phoenix, AZ
Any Age
All Sexes
Metastatic
Phoenix, AZ
Any Age
All Sexes
This study is evaluating whether a new technology can be used to determine a tumor's molecular makeup and mutations.
pharmacological study
Rochester, MN
< 65
All Sexes
Grade III
Rochester, MN
< 65
All Sexes
This study is evaluating whether a stem cell transplant can be used to treat neuroblastoma.
Temsirolimus
Fort Worth, TX
Any Age
All Sexes
Phase 2
Grade II
Fort Worth, TX
Any Age
All Sexes
This study is evaluating whether a combination of chemotherapy drugs and monoclonal antibodies is more effective than chemotherapy drugs alone in treating younger patients with neuroblastoma.
Hu3F8 With GM-CSF
New York, NY
Any Age
All Sexes
Phase 1 & 2
Metastatic
New York, NY
Any Age
All Sexes
This study is evaluating whether a drug called Hu3F8 combined with GM-CSF is safe for treating neuroblastoma.
Lenalidomide
Boston, MA
< 65
All Sexes
Phase 1
Grade I
Boston, MA
< 65
All Sexes
This study is evaluating the side effects and best dose of lenalidomide when given together with dinutuximab with or without isotretinoin in treating younger patients with neuroblastoma that does not respond to treatment or that has come back
DFMO
Nashville, TN
< 65
All Sexes
Phase 2
Nashville, TN
< 65
All Sexes
The purpose of this research study is to evaluate a new investigational drug to prevent reoccurrence of neuroblastoma that is in remission. This study drug is called DFMO. The objectives of this study will be to monitor for safety and look at efficacy of DFMO. The safety of the proposed d…
Humanized 3F8 Monoclonal Antibody (Hu3F8)
New York, NY
Any Age
All Sexes
Phase 1
Metastatic
New York, NY
Any Age
All Sexes
This study is evaluating whether Hu3F8 is safe for treating neuroblastoma and other cancers.
FLT-PET
Detroit, MI