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Combination Chemotherapy for Neuroblastoma
Study Summary
This trial is testing a combination of 3 different chemo drugs to treat neuroblastoma in children. The goal is to see if it is safe and effective.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2023 Phase 2 trial • 27 Patients • NCT04002401Trial Design
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Who is running the clinical trial?
Media Library
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Frequently Asked Questions
Are there any availabilities for participants in this research project?
"This medical research is still recruiting patients, as indicated by clinicaltrials.gov records that show the trial was first posted on June 22nd 2021 and updated most recently on August 11th 2022."
Is this trial accessible to those of advanced age?
"The eligibility requirements for this trial stipulate that qualified candidates be between 1 and 13 years old. On clinicaltrials.gov, 595 trials are available to minors, while 1447 studies accept geriatric patients."
Has this medical trial been previously attempted?
"Since its initial trial, sponsored by Alfacell in 1997 and involving 300 patients, Cyclophosphamide has been subject to considerable research. This culminated in the Phase 3 drug approval for this medication. Currently, 1675 trials are underway across 83 countries with 3640 sites participating."
What precedent has been set for Cyclophosphamide research?
"Presently, there are 1675 on-going Cyclophosphamide clinical trials with 406 in their third phase of research. While many studies for this drug occur near Bethesda, Maryland, they also take place at over 76k sites worldwide."
How many participants have been enrolled in this clinical experiment?
"Yes, the information hosted on clinicaltrials.gov verifies that this medical trial is currently recruiting for participants. The study was initially posted on June 22nd 2021 and recently modified on August 11th 2022, with a total of 15 patients being sought after by one location."
Would I be eligible to join this research project?
"This medical trial is actively recruiting 15 participants between the ages of 1 and 13 who have been clinically diagnosed with neuroblastoma. In addition to meeting this criteria, candidates must also abide by creatinine threshold values based on their age that were derived from a Schwartz formula outlined in Centers for Disease Control data. Furthermore, potential recruits will need to provide consent acknowledging they are aware of the experimental nature of treatment, no more than one cycle of chemotherapy has already been administered, shortening fraction must be ≥ 27% or ejection fraction needs to exceed 50%, total bilirubin levels should not surpass 1.5x normal upper limit for age"
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