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Behavioural Intervention

Home-Based End of Life Care for Blood Cancers

N/A

Waitlist Available

Led By Areej El-Jawahri, MD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosed with relapsed or refractory hematologic malignancy

Must be receiving treatment with non-curative intent or supportive care alone based on the intent of chemotherapy as reported in order entry or Electronic Health Record

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial is testing a new way to care for patients with cancer that has spread through their body. The care includes monitoring the patient's health from a distance and providing support for them at home.

Who is the study for?

This trial is for adults over 18 with advanced blood cancers who are not seeking curative treatment but rather supportive care, as determined by their oncologist. They must be able to communicate in English (with help if needed) and live within 50 miles of MGH. Patients still eligible for clinic-based transfusions can join, except those with uncontrolled psychiatric issues or impaired cognition.Check my eligibility

What is being tested?

The study tests a home-based end-of-life care program called 'Optimize End of Life Care at Home,' which includes remote patient monitoring and support services for individuals with severe hematologic malignancies.See study design

What are the potential side effects?

Since this intervention focuses on supportive care rather than medication, side effects may include emotional distress or discomfort related to the end-of-life process rather than typical drug-related reactions.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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My blood cancer has returned or is not responding to treatment.

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I am receiving treatment to manage symptoms, not to cure my cancer.

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I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Enrollment Rate

Retention Rate

Secondary outcome measures

Acceptability of the intervention

Caregiver Burden

Caregiver Quality of Life (CareGiver Oncology QOL)

+6 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: End of Life (EOL) Care at at HomeExperimental Treatment1 Intervention

End of Life (EOL) Care at at Home intervention entails the following: patient-reported symptoms and home monitored vital signs and body weight with appropriate triggers for phone calls and home visits, and regular communication with oncology clinicians regarding care delivered at home to ensure continuity of care.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Medically HomeUNKNOWN

1 Previous Clinical Trials

300 Total Patients Enrolled

Massachusetts General HospitalLead Sponsor

2,928 Previous Clinical Trials

13,198,250 Total Patients Enrolled

1 Trials studying Blood Cancers

90 Patients Enrolled for Blood Cancers

Areej El-Jawahri, MDPrincipal InvestigatorMassachusetts General Hospital

18 Previous Clinical Trials

4,407 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the aim of this research initiative?

"The primary metric monitored during this 6-month trial is the enrollment rate. Among other measures, secondary outcomes include Caregiver Quality of Life (CareGiver Oncology QOL), Patient Symptom Burden (using the Edmonton Symptom Assessment Scale-revise) and Caregiver Satisfaction with patient's end of life (EOL) care using the FAMCARE; all these will be assessed by means of respective scales ranging from 0 to 100 points or 24 respectively, where higher scores denote more favourable results."

Answered by AI

Is there currently an opportunity for individuals to join this research experiment?

"Affirmative. Clinicaltrials.gov displays that this trial, which first appeared on February 26th 2021, is currently seeking participants. 105 individuals must be recruited from a single medical site to meet the goals of the study."

Answered by AI

To what extent are people participating in this experiment?

"Indeed. Clinicialtrials.gov affirms that this clinical study, first posted on February 26th 2021, is currently recruiting participants and requires 105 volunteers from a single medical centre."

Answered by AI

Recent research and studies

BMC CancerJournal

Supportive Oncology Care at Home Interventions: Protocols for Clinical Trials to Shift the Paradigm of Care for Patients with Cancer

Nipp, Ryan D., Eliza Shulman, Melissa Smith, Patricia M. C. Brown, P. Connor Johnson, Eva Gaufberg, Charu Vyas, et al.. 2022. “Supportive Oncology Care at Home Interventions: Protocols for Clinical Trials to Shift the Paradigm of Care for Patients with Cancer”. BMC Cancer. Springer Science and Business Media LLC. doi:10.1186/s12885-022-09461-z.

clinicaltrials.govStudy

Hospital at Home at EOL in Heme Malignancies

El-Jawahri, Areej,M.D. 2021. "Hospital at Home at EOL in Heme Malignancies". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04690205.