Social Determinants for Cancer
(EDPO Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore differences in cancer treatment by collecting data from patients receiving advanced cancer care, focusing on clinical details and factors such as social conditions and genetics. It includes both Black and non-Black patients to understand how treatments may vary across different groups. The trial targets individuals with advanced cancer who are already planning to undergo molecular testing as part of their usual treatment. Participants must be able to provide consent and share their health information. As an unphased trial, this study offers patients the opportunity to contribute to a deeper understanding of cancer treatment across diverse populations.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that the Social Determinants of Health Questionnaires are safe?
Research shows that using Social Determinants of Health Questionnaires is safe. These questionnaires help researchers understand how factors like location and resource access affect health. Studies have used these questionnaires to collect data without any direct risk to participants.
No reports indicate adverse effects from completing these questionnaires. They serve as a tool for gathering information, similar to taking a survey. This process helps doctors and researchers learn more about the link between social factors and health, especially in cancer care. Therefore, participating in this type of study should be safe and straightforward.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to uncover disparities in precision oncology treatments between Black patients and non-Black patients with advanced cancer. Precision oncology focuses on tailoring treatments based on individual genetic differences, but not everyone may have equal access or response to these advances. By identifying and understanding these disparities, the trial hopes to ensure that all patients can benefit equally from personalized cancer therapies. This could lead to more equitable healthcare outcomes and potentially uncover new ways to optimize treatment effectiveness across diverse populations.
What evidence suggests that using Social Determinants of Health Questionnaires is effective for understanding cancer outcomes?
Research has shown that location and financial status can significantly impact cancer outcomes. Studies indicate that individuals facing financial difficulties have a 22% higher risk of dying from cancer compared to those without such challenges. This trial will explore these social determinants by focusing on different groups, including Black patients with advanced cancer and non-Black patients with advanced cancer. By addressing these social factors, cancer screenings have become 8.4% more effective at detecting cancer. Tackling these issues can help reduce disparities in cancer care, especially for marginalized groups. Understanding and addressing these factors may lead to better cancer outcomes.12367
Who Is on the Research Team?
Bryan P Schneider, MD
Principal Investigator
Indiana University
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Data Collection
Collection of detailed clinical, social determinant, and genomic data from patients
Follow-up
Participants are monitored for survival and toxicity outcomes
What Are the Treatments Tested in This Trial?
Interventions
- Social Determinants of Health Questionnaires
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Find a Clinic Near You
Who Is Running the Clinical Trial?
Indiana University
Lead Sponsor
Citations
Evaluating Social Determinants of Health Related to ...
Social determinants of health posit that negative outcomes are influenced by individuals living in underserved and underresourced neighborhoods.
Social Determinants of Health Screening Influence Cancer ...
Patients with socioeconomic disparity experience a 22% higher cancer mortality rate compared to those without socioeconomic disparity.
Social Determinants of Health and Cancer Care
Given that SDOH are associated with stark disparities in cancer outcomes across the care continuum for both adults and children, expanding the ...
4.
acsjournals.onlinelibrary.wiley.com
acsjournals.onlinelibrary.wiley.com/doi/full/10.3322/caac.21801Social determinants of health and US cancer screening ...
SDOH interventions increased screening rates overall by a median of 8.4 percentage points (interquartile interval, 1.8–18.8 percentage points).
Integration of social determinants of health in quality ...
Although SDoH shape patterns cancer risk and access to screening which results in advanced stage at diagnosis for marginalized groups ...
6.
sirenetwork.ucsf.edu
sirenetwork.ucsf.edu/tools-resources/resources/collecting-data-social-determinants-health-advance-health-equity-cancer?destination=undefinedCollecting data on the social determinants of health to ...
Collecting data on the social determinants of health to advance health equity in cancer care in Canada: Patient and community perspectives.
Social determinants of health and US cancer screening ...
Data items included study and intervention characteristics, SDOH intervention components and measures, and screening outcomes. The findings were ...
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