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RN-Led Palliative and Supportive Care for Acute Myeloid Leukemia

N/A

Waitlist Available

Led By Ashley Bryant, PhD, RN

Research Sponsored by UNC Lineberger Comprehensive Cancer Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Receive low-dose cytarabine or hypomethylating agent (HMA) in combination with Venetoclax chemotherapy

Diagnosis of acute myeloid leukemia

Timeline

Screening 3 weeks

Treatment Varies

Follow Up throughout the study, around 6-9 months

Awards & highlights

Study Summary

This trial looks at a new way to provide palliative and supportive care to older adults with acute leukemia during their hospital stay. It includes registered nurses, occupational therapists, and physical therapists working together to address the patients' needs.

Who is the study for?

This trial is for adults over 60 with acute myeloid leukemia who are getting low-dose cytarabine or HMA with Venetoclax chemo. They must speak and read English. Caregivers identified by the patient can also join if they're adults who speak English. People in hospice care cannot participate.Check my eligibility

What is being tested?

The study tests a new supportive care approach called PACT, provided by nurses, occupational therapists, and physical therapists to help older adults manage daily activities during their hospital stay for leukemia treatment.See study design

What are the potential side effects?

Since this trial focuses on palliative and supportive care rather than direct medical treatments, side effects are not the primary concern; however, typical side effects from standard chemotherapy may still occur.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am receiving low-dose cytarabine or HMA with Venetoclax.

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I have been diagnosed with acute myeloid leukemia.

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I am 18 years old or older.

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I am 60 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ throughout the study, around 6-9 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~throughout the study, around 6-9 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and throughout the study, around 6-9 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Secondary outcome measures

Activities of daily living as assessed by Performance Assessment of Self-Care Skills (PASS)

Aerobic capacity and endurance assessed by 6 minute walk test

Caregiver's physical and mental health assessed by PROMIS 29+2

+22 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: InterventionExperimental Treatment1 Intervention

Patients in the intervention arm will receive the PACT intervention provided by a multidisciplinary team of RNs, OTs, and PTs.

Group II: ControlActive Control1 Intervention

Patients in the control arm will receive standard of care and no intervention.

0 / 4Eligibility criteria met

Find a Location

Who is running the clinical trial?

UNC Lineberger Comprehensive Cancer CenterLead Sponsor

351 Previous Clinical Trials

88,260 Total Patients Enrolled

National Institute of Nursing Research (NINR)NIH

580 Previous Clinical Trials

10,376,492 Total Patients Enrolled

Ashley Bryant, PhD, RNPrincipal InvestigatorUniversity of North Carolina, Chapel Hill

1 Previous Clinical Trials

18 Total Patients Enrolled

Media Library

Palliative And supportive Care inTervention (ACT) Clinical Trial Eligibility Overview. Trial Name: NCT04570709 — N/A

Acute Myeloid Leukemia Research Study Groups: Intervention, Control

Acute Myeloid Leukemia Clinical Trial 2023: Palliative And supportive Care inTervention (ACT) Highlights & Side Effects. Trial Name: NCT04570709 — N/A

Palliative And supportive Care inTervention (ACT) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04570709 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any openings left for those wishing to join this clinical trial?

"According to data found on clinicaltrials.gov, recruitment for this research project has commenced and is ongoing since its initial posting date of September 14th 2020, with the latest update being made October 4th 2022."

Answered by AI

How many individuals are being recruited for the research project?

"Affirmative. According to the details provided on clinicaltrials.gov, this trial is currently accepting patients and was initially posted in September 2020 with updates made as recently as October 2022. 40 individuals are being sought from a single medical centre for participation."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

RN-Led Palliative and Supportive Care Intervention

2020. "RN-Led Palliative and Supportive Care Intervention". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04570709.