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Evorpacept + Venetoclax + Azacitidine for Acute Myeloid Leukemia
Study Summary
This trial will test a new combination therapy for treating patients with acute myeloid leukemia.
- Acute Myeloid Leukemia
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- You have not received any previous treatment with drugs that target CD47 or SIRPalpha proteins.
- Group 1: evorpacept (ALX148) + venetoclax + azacitidine
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Could you provide a breakdown of the medical centers participating in this trial across the state?
"Currently, this clinical trial is enrolling patients from 5 different sites. These locations are Buffalo, Chicago and Nashville in addition to 2 other cities. To reduce travel expenses for participants, it would be prudent to choose the closest medical centre."
What utilization is most common for evorpacept?
"Evorpacept is a commonly used medication for induction chemotherapy. Furthermore, it has been effective in treating refractory anemias, leukemia, myelocytic forms of acute and multilineage dysplasia."
Are there any current opportunities to join this exploratory research?
"As indicated on clinicaltrials.gov this trial, initially posted 5/5/2021 and last updated 6/7/2022, is not currently accepting new participants. Nonetheless, there are 1,879 other studies actively searching for volunteers at the moment."
How many participants are enrolled in this experiment?
"Unfortunately, this trial is no longer enrolling participants. It was initially posted on May 5th 2021 and had its last update on June 7th 2022. If you are looking for a different study to join, there are 1539 trials actively recruiting patients with leukemia or myeloid diseases and 340 studies that accept enrollees for evorpacept treatment."
Has there been any precedent for research utilizing evorpacept?
"The initial research of evorpacept commenced at the Chinese University of Hong Kong-Prince of Wales Hospital in 2006, with 208 trials having been completed to date. Currently there are 340 ongoing investigations, and numerous sites located in Buffalo, New york are participating."
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