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Angiotensin Receptor Neprilysin Inhibitor

one arm for Heart Failure

N/A
Waitlist Available
Led By Gordon W Moe, MD, MSc
Research Sponsored by Unity Health Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, 2 weeks, 4 weeks, 6 months, and 12 months
Awards & highlights

Study Summary

The purpose of this study is to compare the changes in B-type Natriuretic Peptide (BNP) and amino-terminal fragment of proBNP (NT-proBNP) in outpatients managed in the heart failure (HF) clinic initiated on the Angiotensin Receptor Neprilysin Inhibitor (Entresto) and directly compare the prognostic values of BNP and NT-proBNP in patients admitted with acute decompensated HF.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, 2 weeks, 4 weeks, 6 months, and 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 2 weeks, 4 weeks, 6 months, and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
In Patient Protocol
Out Patient Protocol

Trial Design

1Treatment groups
Experimental Treatment
Group I: one armExperimental Treatment1 Intervention
One arm study patients where NT-proBNP and BNP tests will be monitored.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Sacubitril
FDA approved

Find a Location

Who is running the clinical trial?

Alere, Inc.Industry Sponsor
3 Previous Clinical Trials
1,189 Total Patients Enrolled
1 Trials studying Heart Failure
930 Patients Enrolled for Heart Failure
Unity Health TorontoLead Sponsor
540 Previous Clinical Trials
447,480 Total Patients Enrolled
12 Trials studying Heart Failure
7,183 Patients Enrolled for Heart Failure
Gordon W Moe, MD, MScPrincipal InvestigatorUnity Health Toronto

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Comparison of BNP and NT-proBNP in the Management of Patients With Chronic and Acute Heart Failure
2016. "Comparison of BNP and NT-proBNP in the Management of Patients With Chronic and Acute Heart Failure". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04107220.
All > Entresto > Diovan
~34 spots leftby May 2025
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