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Harm Reduction for PTSD (NOC Trial)
NOC Trial Summary
This trial is testing if reducing THC in regular cannabis smokers using a CM intervention can help PTSD symptoms in U.S. veterans.
NOC Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowNOC Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.NOC Trial Design
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Who is running the clinical trial?
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- You are currently at high risk of harming yourself based on a suicide risk assessment called C-SSRS.I have been diagnosed with PTSD and have had symptoms for at least 6 months.You have an IQ score of 80 or higher.I have been diagnosed with PTSD and have had symptoms for at least 6 months.You are currently seeking help for addiction to marijuana.You use cannabis regularly, at least four times a month.You use cannabis.You use cannabis at least four times per month.I do not have any major health issues.You are currently struggling with drug addiction, except for nicotine, mild or moderate alcohol use, and cannabis addiction.
- Group 1: THC Reduction Group
- Group 2: Naturalistic Group
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does the age threshold for this experiment include those over 45 years old?
"This trial's minimum age of enrollment is 19 and it caps at 69 years old."
Is this trial currently accepting new participants?
"The search for participants is still ongoing, as evidenced by the clinicaltrials.gov data which indicates that this medical study went live on May 25th 2022 and was revised most recently on May 17th of the same year."
How many participants have been accepted into this research project?
"Affirmative, the reports on clinicaltrials.gov declare that this medical study is currently seeking participants. It was first posted on May 25th 2022 and last updated on May 17th of the same year. The trial requires 215 patients to be enrolled from one healthcare facility."
Which types of participants are ideal for this research?
"This trial is enlisting 215 individuals aged 19 to 69 that are suffering from suicidal ideations. To qualify, applicants must meet DSM-5 criteria for PTSD with symptoms persisting at least 6 months, be competent enough to provide informed consent, demonstrate an IQ score of greater than 80, have a history in the US Armed Forces and report cannabis use on more than 4 occasions per month as well as test positive for THC in urine drug screen."
What outcome is this research attempting to attain?
"This clinical trial will track participants' Change in Clinician-Administered PTSD Scale for DSM-5 Total Severity Score (CAPS-5) from Baseline to 2 weeks, 12 weeks, 3 months 6 months and 12 months post baseline. Secondary outcomes include a change in General Health Survey (Short form 36), Wisconsin Card Sort Task and Quality of Life Inventory scores over the same time frame; all three are measured on a numerical scale with higher numbers indicating better study results."
Who else is applying?
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How old are they?
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What portion of applicants met pre-screening criteria?
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