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Glaucoma Drops for Glaucoma

N/A
Waitlist Available
Led By Mark Latina
Research Sponsored by Advanced Glaucoma Specialists
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Diagnosis of Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma, Ocular Hypertension
On no systemic medications known to increase IOP (e.g. steroids)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is testing whether two drugs, Cosopt and Xalatan, can help people with glaucoma or ocular hypertension by reducing intraocular pressure.

Who is the study for?
This study is for adults over 18 with mild to moderate open-angle or pseudoexfoliative glaucoma, or ocular hypertension. Participants can be newly diagnosed or on up to two topical medications but not systemic meds that increase eye pressure. They must have decent vision and no recent eye surgery.Check my eligibility
What is being tested?
The trial compares the effectiveness of two FDA-approved glaucoma drops, Cosopt and Xalatan, in reducing eye pressure after a laser treatment called SLT. About 30 participants will receive either drug if their eye pressure remains high post-SLT to determine which is more effective.See study design
What are the potential side effects?
Cosopt may cause side effects like stinging in the eyes, taste changes, and fatigue. Xalatan can lead to redness in the eyes, eyelash growth changes, and darkening of iris color. Both drugs aim to reduce intraocular pressure but individual reactions may vary.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have been diagnosed with a specific type of glaucoma or high eye pressure.
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I am not taking any medications that can raise my eye pressure.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Reduction in Intraocular Pressure

Find a Location

Who is running the clinical trial?

Advanced Glaucoma SpecialistsLead Sponsor
Merck Sharp & Dohme LLCIndustry Sponsor
3,886 Previous Clinical Trials
5,054,523 Total Patients Enrolled
Mark LatinaPrincipal InvestigatorAdvanced Glaucoma Specialist

Media Library

Treatment Clinical Trial Eligibility Overview. Trial Name: NCT00440336 — N/A
Open-Angle Glaucoma Research Study Groups:
Open-Angle Glaucoma Clinical Trial 2023: Treatment Highlights & Side Effects. Trial Name: NCT00440336 — N/A
Treatment 2023 Treatment Timeline for Medical Study. Trial Name: NCT00440336 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are any participants currently being sought for this experiment?

"Unfortunately, this particular clinical trial is not actively recruiting at the moment. According to clinicaltrials.gov, it was first posted on October 1st 2006 and last edited on February 28th 2007. Nonetheless, there are numerous other studies that require participants right now - 215 trials in total!"

Answered by AI

Who else is applying?

What site did they apply to?
Advanced Glaucoma Specialist
What portion of applicants met pre-screening criteria?
Met criteria

Why did patients apply to this trial?

Desire to address high eye pressure resulting in glaucoma.
PatientReceived 2+ prior treatments
Recent research and studies
clinicaltrials.govStudy
Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.
2006. "Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00440336.
All > Glaucoma Boston > Paid Studies Massachusetts
~2 spots leftby Apr 2025
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