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Alcohol

Ethanol for Alcohol Analgesia

N/A

Waitlist Available

Led By Jeff Boissoneault, PhD

Research Sponsored by University of Florida

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

- Consume at least 1 drink/month over the past 6 months

Be between 18 and 65 years old

Must not have

Be younger than 18 years old

Be older than 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Upday 1; day 2 (laboratory sessions will be separated by at least 48 hours.)

Awards & highlights

Study Summary

This trial will study how different people react to drinking alcohol to self-medicate pain.

Eligible Conditions

Effects of Family History of Alcoholism and Sex on Alcohol Analgesia

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below

Select...

You have consumed alcohol at least once a month for the past 6 months.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ day 1; day 2 (laboratory sessions will be separated by at least 48 hours.)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~day 1; day 2 (laboratory sessions will be separated by at least 48 hours.)

This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1; day 2 (laboratory sessions will be separated by at least 48 hours.) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Activity of Pain-related Brain Regions during Painful Stimulation

Change in Connectivity of Pain-related Brain Regions during Painful Stimulation

Change in Heat Pain Ratings

+3 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Family History PositiveExperimental Treatment2 Interventions

People reporting at least one parent with a history of alcohol problems.

Group II: Family History NegativeExperimental Treatment2 Interventions

People who do not report having a parent with a history of alcohol problems.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Ethanol

2005

Completed Phase 4

~3000

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of FloridaLead Sponsor

1,308 Previous Clinical Trials

705,916 Total Patients Enrolled

National Institute on Alcohol Abuse and Alcoholism (NIAAA)NIH

775 Previous Clinical Trials

1,349,035 Total Patients Enrolled

Jeff Boissoneault, PhDPrincipal InvestigatorAssistant Professor

2 Previous Clinical Trials

99 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this medical trial accept individuals over fifty years of age?

"Eligibility for this clinical trial is contingent upon an individual being over the age of majority and no older than 45."

Answered by AI

What is the current enrollment count for this trial?

"Affirmative. Clinicaltrials.gov reports that this medical research, initially posted on November 20th 2018, is actively recruiting participants. Approximately 110 people are sought from 1 distinct site."

Answered by AI

In what situations is Ethanol commonly utilized?

"Ethanol is a widely accepted treatment for obstructive hypertrophic cardiomyopathy, as well as communicable illnesses, ethylene glycol poisoning, and certain skin disinfection therapies."

Answered by AI

Could I be enrolled in this investigation?

"110 candidates of legal drinking age and under 45 years old are sought for this trial, who have habitually partaken in alcohol consumption during the last half-year. A critical requirement is that they must consume at least one alcoholic beverage monthly."

Answered by AI

Is there ongoing enrollment for this research experiment?

"As revealed on clinicaltrials.gov, this trial is open to participants and recruiting. It was initially posted in November 2018 and the last time it underwent an update was August 1st 2022."

Answered by AI

Recent research and studies

Alcoholism: Clinical and Experimental ResearchJournal

Acute Alcohol Intake Produces Widespread Decreases in Cortical Resting Signal Variability in Healthy Social Drinkers

Sevel, Landrew, Bethany Stennett, Victor Schneider II, Nicholas Bush, Sara Jo Nixon, Michael Robinson, and Jeff Boissoneault. 2020. “Acute Alcohol Intake Produces Widespread Decreases in Cortical Resting Signal Variability in Healthy Social Drinkers”. Alcoholism: Clinical and Experimental Research. Wiley. doi:10.1111/acer.14381.

Drug and Alcohol DependenceJournal

Acute Alcohol Intake Alters Resting State Functional Connectivity of Nucleus Accumbens with Pain-related Corticolimbic Structures

Boissoneault, Jeff, Bethany Stennett, and Michael E. Robinson. 2020. “Acute Alcohol Intake Alters Resting State Functional Connectivity of Nucleus Accumbens with Pain-related Corticolimbic Structures”. Drug and Alcohol Dependence. Elsevier BV. doi:10.1016/j.drugalcdep.2019.107811.

clinicaltrials.govStudy

Characterizing the Effects of Family History of Alcoholism on Alcohol Analgesia

2018. "Characterizing the Effects of Family History of Alcoholism on Alcohol Analgesia". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04925076.