Ketamine for Suicidal Ideation

Waitlist Available · 18+ · All Sexes · Fort Sam Houston, TX

This study is evaluating whether a drug or a drug plus a placebo can reduce suicidal thoughts in people with acute suicidal ideation.

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About the trial for Suicidal Ideation

Eligible Conditions
Suicide · Emergencies · Suicidal Ideation

Treatment Groups

This trial involves 3 different treatments. Ketamine is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are not being studied for commercial purposes.

Experimental Group 1
Control Group 2
Control Group 3

About The Treatment

First Studied
Drug Approval Stage
How many patients have taken this drug
FDA approved


This trial is for patients born any sex aged 18 and older. There is one eligibility criterion to participate in this trial as listed below.

Inclusion & Exclusion Checklist
Mark “yes” if the following statements are true for you:
Patients age 18 to less than 75 who present to the SAMMC ED with either overt or incidental suicidal ideations with a SADPERSONS score 5 or greater that the treating provider feels warrant formal evaluation.
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Odds of Eligibility
Be sure to apply to 2-3 other trials, as you have a low likelihood of qualifying for this one.Apply To This Trial
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Approximate Timelines

Please note that timelines for treatment and screening will vary by patient
Screening: ~3 weeks
Treatment: varies
Reporting: 2 hours
Screening: ~3 weeks
Treatment: Varies
Reporting: 2 hours
This trial has approximate timelines as follows: 3 weeks for initial screening, variable treatment timelines, and reporting: 2 hours.
View detailed reporting requirements
Trial Expert
Connect with the researchersHop on a 15 minute call & ask questions about:
- What options you have available- The pros & cons of this trial
- Whether you're likely to qualify- What the enrollment process looks like

Measurement Requirements

This trial is evaluating whether Ketamine will improve 1 primary outcome in patients with Suicidal Ideation. Measurement will happen over the course of 2 hours.

Change in Beck Scale for Suicidal Ideation

Who is running the study

Principal Investigator
S. S.
Steven Schauer, CPT
Brooke Army Medical Center

Patient Q & A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What causes suicidal ideation?

Data from a recent study confirms the strong relationship between suicidal ideation and suicidal behavior. The clinical implications are that risk can be assessed at the initial assessment, suicide prevention strategies may be applied, and treatment may be helpful.

Anonymous Patient Answer

Can suicidal ideation be cured?

Patients with a history of suicidal ideation should be questioned about suicidal thoughts at intervals following cessation of use of psychoactive drugs with the potential for abuse, as a method of suicide, and as an indicator of psychiatric disturbance. In addition, we can propose that this approach may be useful in the initial assessment of patients with suicidal ideation.

Anonymous Patient Answer

What are common treatments for suicidal ideation?

Of 3,931 people who had received treatment for suicidal ideation at the hospital, most were treated using nonspecific therapies (n=2230; 82.8% of respondents). Patients who received specific therapy (n=491; 13.9%) and who were discharged after discharge (n=939; 26.1%) reported fewer symptoms at follow-up; however, these differences were not statistically significant.

Anonymous Patient Answer

What is suicidal ideation?

There are strong correlations between suicidal ideation and suicide attempts and other related factors. Identifying suicidal ideation in general and specific suicidal attempts, motives, and methods are imperative.

Anonymous Patient Answer

What are the signs of suicidal ideation?

The key signs and symptoms of suicidal ideation are sudden intensification or intensification of suicidal thoughts (such as thoughts of death, suicide, or harm to the self), and/or behaviors (such as attempted or completed self-injury, suicide attempts, and/or attempts to end one's life). These behaviors, as well as the individual's attempts to decrease the consequences of the behavior, constitute the spectrum of the illness.

Anonymous Patient Answer

How many people get suicidal ideation a year in the United States?

Approximately 5% of Americans have suicidal ideation in a given year. The frequency of suicide attempts is lower than that of ideation, although an increasing number of attempts are being made in this population.

Anonymous Patient Answer

Who should consider clinical trials for suicidal ideation?

The suicidal ideation in our cohort might be associated less from psychiatric disorders than the patients with mood symptoms. Those depressive disorders with suicidal attempts can be treated and may benefit from treatment with antidepressants.

Anonymous Patient Answer

Is ketamine safe for people?

Ketamine is safe for self-treatment, with a low risk of fatal overdose, and is not a risk factor for psychiatric disorders. Ketamine has potentially significant social, legal, and recreational advantages, as well as potential for self-administration.

Anonymous Patient Answer

What does ketamine usually treat?

Ketamine can be used to help those who have symptoms of posttraumatic stress disorder, suicidal ideation, and alcohol addiction. It can be used for short-term treatments of people who have suicidal thoughts, and can be used when combined with counseling.

Anonymous Patient Answer

Have there been other clinical trials involving ketamine?

Ketamine continues to be investigated as a potential antidepressant in patients with depressive disorders. However, no clinical trials with ketamine have been reported to date. This report describes a new clinical trial related to ketamine treatment for suicidal ideation in depressed out-patients. There has been some preliminary evidence that ketamine may well be efficacious in reducing the urge for suicidal behavior, and an additional study is currently being planned.

Anonymous Patient Answer

What are the latest developments in ketamine for therapeutic use?

(1) Ketamine may be an appropriate treatment for suicidal ideation in schizophrenia; (2) the use of ketamine is not without risks for suicidal behavior in psychiatric patients regardless of whether they may also present comorbid depression; (3) the antidepressant effectiveness of ketamine remains to be established.

Anonymous Patient Answer

Have there been any new discoveries for treating suicidal ideation?

There remain significant limitations for the therapeutic interventions tested in randomized controlled trials. The lack of significant results may be attributed to multiple factors, including: 1) the number of trials performed; 2) inadequate intervention dosing; 3) inclusion of less aggressive trial designs; 4) the non-random assignment of the tested interventions; 5) the short follow-up periods of reported trials. Consequently, we recommend that the use of such interventions must be regarded with special caution until proven effective at preventing suicide, by showing significant efficacy in improving an important outcome (i.e. reduced morbidity or increased survival).

Anonymous Patient Answer
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