Study Summary
This trial is testing whether ketamine can rapidly reduce depression and suicide severity in children, which could be a safer and more effective alternative to involuntary hospitalization.
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
0 Primary · 7 Secondary · Reporting Duration: 24 hours, 7-, 14-, 21-, and 28 days
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
3 Treatment Groups
Intravenous midazolam
1 of 3
Intravenous ketamine
1 of 3
Intravenous saline
1 of 3
Active Control
Experimental Treatment
Non-Treatment Group
96 Total Participants · 3 Treatment Groups
Primary Treatment: Ketamine Injectable Solution · Has Placebo Group · Phase 1 & 2
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 10 - 17 · All Participants · 7 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:Who else is applying?
What state do they live in?
| Tennessee | 100.0% |
How old are they?
| 18 - 65 | 100.0% |
What portion of applicants met pre-screening criteria?
| Did not meet criteria | 100.0% |
Frequently Asked Questions
Are any geriatric patients partaking in this research endeavor?
"This clinical study requires participants to be aged between 10 and 17 years old." - Anonymous Online Contributor
How many individuals are capable of participating in this clinical trial?
"Indeed, clinicaltrials.gov reports that the trial is currently in need of participants. It was initially posted on June 1st 2022 and most recently updated on November 3rd 2022. The research requires 96 patients to be recruited from a single medical centre." - Anonymous Online Contributor
Is there a possibility that I may be enrolled in this experiment?
"This clinical trial is recruiting 96 minors between 10 and 17 years old exhibiting suicidal ideation. To be eligible, they must have responded affirmatively to either Passive or Active Ideation on the C-SSRS, given consent for admission into an inpatient facility via Capacity to Assent protocol and show no neurological anomalies as evaluated by a paediatric psychiatrist. Additionally, their vitals will need to fall within age appropriate norms." - Anonymous Online Contributor
Are there still enrollment opportunities for those interested in participating in this medical research?
"Affirmative. According to the information posted on clinicaltrials.gov, this medical investigation was initially listed on June 1st 2022 and recently modified in November 3rd of the same year. Consequently, 96 individuals are needed for enrollment at a single site." - Anonymous Online Contributor
In what instances is Ketamine Injectable Solution regularly prescribed?
"Ketamine Injectable Solution has been applied to manage seizures, epileptic episodes, amnesia and other therapeutic procedures." - Anonymous Online Contributor