Plasma Tear Drops for Dry Eye Syndrome
What You Need to Know Before You Apply
What is the purpose of this trial?
This is a single center double-masked study with up to four visits. Subjects who have been diagnosed with dry-eye syndrome at Flaum Eye Institute will be enrolled. The purpose of the study is to determine if using platelet rich plasma drops can improve clinically significant dry eye in patients and determine if there is a difference with using two different uses of the plasma tear drops: platelet rich plasma tears and plasma tears without platelets.
Will I have to stop taking my current medications?
You must stop using any eye drops or topical eye medications at least two weeks before joining the study. The protocol does not specify about other medications, so it's best to discuss with the study team.
Is it safe to use plasma tear drops for dry eye syndrome?
The research on platelet-related products suggests that while platelet storage and transfusion can have adverse effects, these are mostly related to transfusion procedures and not directly applicable to plasma tear drops. Plateletpheresis procedures, which are related to the collection of platelets, are generally considered safe with few adverse events reported.12345
How is the treatment with plasma tear drops different from other treatments for dry eye syndrome?
Plasma tear drops, including platelet-rich plasma (PRP) and platelet-poor plasma, are unique because they use components from the patient's own blood, rich in anti-inflammatory agents and growth factors, to help repair the eye's surface, unlike standard artificial tears that only provide temporary moisture.678910
What data supports the effectiveness of the treatment Platelet Poor Plasma Tear Drops and Platelet Rich Plasma Tear Drops for Dry Eye Syndrome?
Are You a Good Fit for This Trial?
This trial is for individuals with clinically significant dry eye who have no other active eye diseases or allergies. Participants must not be using any eye medications two weeks prior to joining, meet blood donation criteria, and agree to follow the study's instructions. Pregnant individuals or those on antibiotics are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive platelet rich plasma drops or plasma tears without platelets to treat dry eye syndrome
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Platelet Poor Plasma Tear Drops
- Platelet Rich Plasma Tear Drops
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Rochester
Lead Sponsor