← Back to Search

Stepped Care for Depression

N/A
Waitlist Available
Led By Nazanin Alavi, MD, FRCPC
Research Sponsored by Dr. Nazanin Alavi
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 3, 6, 9, 12
Awards & highlights

Study Summary

This trialoffers e-CBT for MDD over 12 weeks to help reduce symptoms. It includes modules, homework, feedback & interaction with therapists. Questionnaires & physiological data will be used to evaluate efficacy. The second arm adds a stepped care approach if needed.

Eligible Conditions
  • Depression

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 3, 6, 9, 12
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 3, 6, 9, 12 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in quality of life (Quality of Life Enjoyment and Satisfaction Questionnaire)
Change in symptoms (Participant Health Questionnaire - 9 Item)
Change in symptoms (Quick Inventory of Depressive Symptoms)

Trial Design

2Treatment groups
Experimental Treatment
Group I: e-CBT + Stepped CareExperimental Treatment2 Interventions
1 - Participant will receive message from assigned care provider on OPTT who check-in with them about strategies and techniques they have discussed and remind them of weekly homework due date. 2.- Participant will receive phone call from therapist who will check-in on them, remind them of therapy strategies, and verbally remind them of weekly homework due date. 3 - Participant will receive phone call from assigned care provider who will check-in on them, remind them of some therapy strategies and techniques and weekly session due date, and provide CBT summary of previously reviewed CBT concepts. 4 - articipant will receive video call (Microsoft Teams) from their therapist who will check-in on them, remind them of weekly session due date, and provide CBT content support to participant. 5 - Participant will receive CBT sessions in live video call (Microsoft Teams) with research psychiatrist involved in care.
Group II: e-CBTExperimental Treatment1 Intervention
12 weekly sessions with approximately 30 slides and interactive content, delivered through OPTT designed to mirror in-person standard CBT. Participants go through the content and complete homework at the end of the session. Homework is submitted through OPTT and reviewed by the therapist assigned to the participant, who will provide personalized feedback within three days of submission. Therapists have access to pre-designed session-specific feedback templates to use as a basic structure to write their feedback. By doing so, the time needed to respond to each patient is reduced and therefore the number of patients each therapist can handle increases. On average, developing this feedback takes a therapist 15-20 minutes per patient. In addition to the weekly feedback, participants have the option to message their therapist through the platform throughout the week regarding any questions or concerns they may have.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Stepped Care
2016
Completed Phase 4
~2380
e-CBT
2021
N/A
~200

Find a Location

Who is running the clinical trial?

Dr. Nazanin AlaviLead Sponsor
12 Previous Clinical Trials
1,037 Total Patients Enrolled
5 Trials studying Depression
495 Patients Enrolled for Depression
Queen's UniversityLead Sponsor
365 Previous Clinical Trials
120,338 Total Patients Enrolled
32 Trials studying Depression
7,074 Patients Enrolled for Depression
Nazanin Alavi, MD, FRCPCPrincipal InvestigatorQueen's University
1 Previous Clinical Trials
100 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the maximum capacity for participants in this trial?

"Yes, according to clinicaltrials.gov, this trial is accepting applications from interested participants. It was first announced on April 7th 2021 and most recently updated October 5th 2022; currently they are seeking 110 subjects based out of 1 locale."

Answered by AI

Is there still space available in this clinical trial for participants?

"Based on records provided by clinicaltrials.gov, this medical trial is actively recruiting participants after first being published on the 7th of April 2021 and last edited on the 5th of October 2022."

Answered by AI

For whom is this investigation suitable?

"This experiment necessitates the recruitment of 110 individuals, aged 18-65 and suffering from major depressive disorder. In addition to these conditions, participants must also be able to consent to the study, converse in English fluently, have regular access to the internet and display competent behaviour throughout the trial."

Answered by AI

Does the eligibility for this study extend to persons under 30 years of age?

"As stated in the requirements for this clinical trial, participants must be of legal age (18) or older and no more than 65 years old."

Answered by AI

Who else is applying?

What state do they live in?
North Carolina
Oregon
How old are they?
18 - 65
What site did they apply to?
Queen's University
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
Recent research and studies
clinicaltrials.govStudy
Incorporating Stepped Care Approach Into e-CBT for Depression
Dr. Nazanin Alavi 2021. "Incorporating Stepped Care Approach Into e-CBT for Depression". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04747873.
~20 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top