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stepped collaborative care for Depression

N/A
Waitlist Available
Led By Jennifer L. Steel, PhD
Research Sponsored by University of Pittsburgh
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
CES-D score >=16
Expected survival < 2 years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline at 4 months, 8 months and 12 months
Awards & highlights

Study Summary

This trial will test whether a stepped collaborative care intervention can reduce depression in cancer caregivers, compared to an enhanced usual care arm. Biobehavioral factors, including changes in health behaviors and biomarkers of inflammation, will be assessed. The investigators also expect to measure metabolic abnormalities and clinical markers of CVD.

Eligible Conditions
  • Cancer
  • Depression

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline at 4 months, 8 months and 12 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline at 4 months, 8 months and 12 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Caregiver Quality of Life Questionnaire
Caregiver's Depression Questionnaire
Caregiver's Perceived Stress Questionnaire
Secondary outcome measures
Caregiver's IL-6, TNFα, fibrinogen, CRP

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: stepped collaborative careExperimental Treatment1 Intervention
At least biweekly contact from a care coordinator by phone and face-to- face visits occurring approximately every 2 months during the patients outpatient visits or treatment, and 24/7 access to a website that was specifically designed during the pilot study for advanced cancer patients from socioeconomically disadvantaged backgrounds.
Group II: Enhanced Usual CareActive Control1 Intervention
Referred to a therapist and/or psychiatrist in their home town depending on the type of treatment they prefer (e.g., behavioral and/or medication)
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
stepped collaborative care
2016
N/A
~10

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor
1,712 Previous Clinical Trials
16,346,410 Total Patients Enrolled
119 Trials studying Depression
34,495 Patients Enrolled for Depression
Jennifer L. Steel, PhDPrincipal InvestigatorUPMC departemnt of surgery
1 Previous Clinical Trials
459 Total Patients Enrolled
1 Trials studying Depression
459 Patients Enrolled for Depression

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the trial currently admitting new participants?

"Data from clinicaltrials.gov shows that this medical study is still looking for participants and has been since December 1st 2016 with the latest edit made on April 4th 2022."

Answered by AI

To what extent has enrollment to this clinical trial increased?

"That is correct. According to clinicaltrials.gov, recruiting for this medical trial first began on December 1st 2016 and the posting was recently updated on April 4th 2022. 450 individuals from two different sites are being sought out for the study."

Answered by AI
~0 spots leftby Mar 2025