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Behavioural Intervention

Common Elements Toolbox- Adult version (COMET-A) for Depression (COMET Trial)

N/A
Waitlist Available
Led By Akash Wasil
Research Sponsored by University of Pennsylvania
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Adult participants (at least 18 years old) will be eligible for this study
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up immediately after the intervention
Awards & highlights

COMET Trial Summary

Digital Mental Health and Wellness Intervention for Adults: A Randomized Control Trial of COMET

Eligible Conditions
  • Depression
  • Anxiety

COMET Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

COMET Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 12 weeks post-intervention
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 12 weeks post-intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Ability to Cope with COVID-19
Change in Generalized Anxiety Disorder Screener-7 (GAD-7)
Change in Patient Health Questionnaire-9 (PHQ-9)
+5 more

COMET Trial Design

3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: COMETExperimental Treatment1 Intervention
Participants receive modules focused on cognitive restructuring, gratitude, behavioral activation and self-compassion. Participants were randomized to receive 3 of the 4 possible modules: behavioral activation, cognitive restructuring, gratitude, and self-compassion.Participants in the intervention condition were randomized to receive descriptions of the four modules at the beginning of the intervention that were phrased to focus on building and improving strengths (positive) or reducing negative emotions and behaviors (negative).
Group II: WaitlistActive Control1 Intervention
Participants filled out all pre-test and post-test measures without having access to COMET of the active control exercises. Participants in this condition will receive access to COMET at the end of the study.
Group III: Self-Awareness ControlPlacebo Group1 Intervention
Participants learn about self-awareness through writing about memories, writing a short argumentative essay, and noticing objects in their surroundings.

Find a Location

Who is running the clinical trial?

University of PennsylvaniaLead Sponsor
2,006 Previous Clinical Trials
42,880,552 Total Patients Enrolled
68 Trials studying Depression
26,908 Patients Enrolled for Depression
Robert J DeRubeis, PhDStudy DirectorUniversity of Pennsylvania
Akash WasilPrincipal InvestigatorUniversity of Pennsylvania
3 Previous Clinical Trials
1,252 Total Patients Enrolled
3 Trials studying Depression
1,252 Patients Enrolled for Depression

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Digital Mental Health and Wellness Intervention for Adults: A Randomized Control Trial of COMET
2021. "Digital Mental Health and Wellness Intervention for Adults: A Randomized Control Trial of COMET". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04586192.
All > Mental Health
~588 spots leftby May 2025
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