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Breath Test for Female Protein Metabolism (FBT Trial)

N/A

Recruiting

Research Sponsored by University of Toronto

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 hours

Awards & highlights

FBT Trial Summary

This trial is testing a new method to measure protein turnover, which is vital for maintaining lean body mass. The method uses a leucine tracer and carbon dioxide detection to see how much leucine is being used to build new proteins. The study will help validate the new method in female participants.

Who is the study for?

This trial is for young adult females aged 18-35 who are generally healthy, have a BMI between 18.5 and 30, and exercise at least once a week. They must not be using oral contraceptives or supplements that affect protein metabolism, nor should they have any medical conditions like diabetes or use drugs that impact muscle growth.Check my eligibility

What is being tested?

The study tests a non-invasive breath test to see how effectively women's bodies use dietary amino acids to build muscle proteins after eating or exercising. It aims to validate this method in females by measuring the oxidation of a leucine tracer in exhaled carbon dioxide.See study design

What are the potential side effects?

Since the intervention involves only breathing into an apparatus after consuming food with the tracer and performing resistance exercises, there are no direct side effects associated with invasive procedures such as blood sampling or muscle biopsies.

FBT Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 hours

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 hours

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Exogenous Leucine Oxidation (umol/kg)

Net-Leucine Retention (umol/kg)

FBT Trial Design

2Treatment groups

Experimental Treatment

Group I: Mid-Luteal PhaseExperimental Treatment2 Interventions

5-7 days after ovulation, determined by self-reports and confirmed with ovulation test kits.

Group II: Mid-Follicular PhaseExperimental Treatment2 Interventions

7-10 days after the onset of menses, determined by self-reports and confirmed with ovulation test kits.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor

689 Previous Clinical Trials

1,018,633 Total Patients Enrolled

Hugo JW Fung, PhD (c)Study DirectorFaculty of Kinesiology and Physical Education

2 Previous Clinical Trials

44 Total Patients Enrolled

Nicki Pourhashemi, MSc StudentStudy DirectorFaculty of Kinesiology and Physical Education

Media Library

Ex-Fed Clinical Trial Eligibility Overview. Trial Name: NCT05422300 — N/A

Female Protein Metabolism Research Study Groups: Mid-Follicular Phase, Mid-Luteal Phase

Female Protein Metabolism Clinical Trial 2023: Ex-Fed Highlights & Side Effects. Trial Name: NCT05422300 — N/A

Ex-Fed 2023 Treatment Timeline for Medical Study. Trial Name: NCT05422300 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what capacity is this clinical trial accepting participants?

"Affirmative. On clinicaltrials.gov, the data suggests that this research project is recruiting candidates; it was initially posted on June 20th 2022 and most recently updated on the same day. The trial requires 10 individuals to be enrolled from a single centre."

Answered by AI

Are there any qualifications for joining this research endeavor?

"This clinical trial is seeking 10 young adults aged 18-35 who currently consume dietary proteins. Additional criteria for eligibility include female gender, body mass index of between 18.5 and 30 kilograms per meter squared, regular menstruation in the three months prior to enrolment, recreational exercise at least once a week for six or more consecutive months before application submission, and an age range spanning from 18 to 35 years old."

Answered by AI

Does this experiment allow senior citizens to participate?

"Participants that meet the requirements for this clinical trial must be in between 18 and 35 years old. For younger and older individuals, 82 trials are available to those under 18 while 160 exist for senior citizens."

Answered by AI

Is this clinical trial currently open to new participants?

"Affirmative. Clinicaltrials.gov conveys that this study is indeed recruiting participants; with the original advertisement posted on June 20th 2022 and last updated on the same date. The trial requires 10 patients from a single medical facility to participate in their research."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A 'Non-Invasive' Breath Test to Determine Anabolic Sensitivity in Females

Daniel Moore 2022. "A 'Non-Invasive' Breath Test to Determine Anabolic Sensitivity in Females". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05422300.