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'Breath Test' for Aging (ARBT Trial)

N/A
Recruiting
Led By Daniel Moore, PhD
Research Sponsored by University of Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Average daily step-count >7,000/day
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6 hours
Awards & highlights

ARBT Trial Summary

This trial will test whether a non-invasive breath test can detect differences in how young and old adults process protein after exercise.

Who is the study for?
This trial is for healthy young (18-35) and older adults (60-80) who are relatively active, walking more than 7,000 steps daily with a BMI of 18.5-29.9. It's not for those using NSAIDs regularly (except low-dose aspirin), unable to follow the protocol, smokers, illicit drug users, or those with chronic illnesses like diabetes or heart disease.Check my eligibility
What is being tested?
The study tests a non-invasive breath test that measures how well different age groups use amino acids after protein intake and physical activity changes. Participants will undergo periods of their usual activity followed by reduced movement to compare results.See study design
What are the potential side effects?
Since this trial involves monitoring through a breath test and changes in physical activity levels rather than medication or invasive procedures, significant side effects are not expected.

ARBT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I walk more than 7,000 steps a day.

ARBT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Exogenous Leucine Oxidation (umol/kg)
Net Leucine Retention (umol/kg)

ARBT Trial Design

2Treatment groups
Active Control
Group I: Young AdultsActive Control2 Interventions
Equal sex distribution (10M/10F); ages 18-35 years old.
Group II: Older AdultsActive Control2 Interventions
Equal sex distribution (6M/6F); ages 60-80 years old.

Find a Location

Who is running the clinical trial?

University of TorontoLead Sponsor
689 Previous Clinical Trials
1,018,611 Total Patients Enrolled
5 Trials studying Dietary Proteins
90 Patients Enrolled for Dietary Proteins
Hugo JW Fung, MScStudy DirectorUniversity of Toronto
1 Previous Clinical Trials
24 Total Patients Enrolled
1 Trials studying Dietary Proteins
24 Patients Enrolled for Dietary Proteins
Daniel Moore, PhDPrincipal InvestigatorUniversity of Toronto
4 Previous Clinical Trials
58 Total Patients Enrolled
2 Trials studying Dietary Proteins
44 Patients Enrolled for Dietary Proteins

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Oral 'Breath Test' to Measure Anabolic Sensitivity in Young and Older Adults at Different Activity Levels
Daniel Moore 2022. "Oral 'Breath Test' to Measure Anabolic Sensitivity in Young and Older Adults at Different Activity Levels". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05216809.
~10 spots leftby Apr 2025
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