Protein Intake for Cancer Patients
What You Need to Know Before You Apply
What is the purpose of this trial?
Severe muscle loss in patients with cancer has been associated with increased physical disability, extended hospitalization, infectious and noninfectious complications, increased risk of severe toxicity during cancer treatment, poor quality of life and shortened survival. Adequate protein is key to sustain muscle mass and overall health. However, current nutritional recommendations are not specific or evidence-based. The aim of this project is to determine the protein needs of patients with colorectal or breast cancer. Protein needs will be determined using a novel, non-invasive approach. Our results will inform nutritional recommendations and guidelines with the ultimate goal of improving outcomes for people with cancer.
Will I have to stop taking my current medications?
The trial protocol does not specify if you need to stop taking your current medications. However, if you have comorbidities or are on medications that interfere with the study, you may not be eligible to participate.
Is protein intake safe for cancer patients?
Protein intake, including supplements like whey protein, is generally safe for cancer patients. Some studies show it can improve body composition and muscle strength without interfering with cancer treatments. However, minor side effects like constipation and diarrhea have been reported in a small number of patients.12345
How does the treatment Phenylalanine differ from other treatments for cancer patients?
Phenylalanine treatment is unique because it involves dietary manipulation to limit phenylalanine intake, which has been shown to reduce tumor growth in animal models and may enhance the body's immune response against certain cancers. This approach is different from traditional cancer treatments that typically involve chemotherapy or radiation.25678
What data supports the effectiveness of the treatment Phenylalanine, L-Phenylalanine for cancer patients?
Research suggests that protein and amino acid supplementation, which includes components like phenylalanine, can help improve muscle mass and strength in cancer patients, potentially leading to better outcomes. Additionally, higher protein intake has been associated with improved survival in breast cancer patients, indicating a possible benefit of protein-related treatments.2491011
Who Is on the Research Team?
Carla Prado, PhD, RD
Principal Investigator
University of Alberta
Are You a Good Fit for This Trial?
This trial is for outpatients aged 45-80 with stage II to III colorectal or breast cancer, who can visit the clinic within 4 weeks of starting chemo or after surgery if no chemo. They must be able to walk and provide samples. Excluded are those with kidney issues, abnormal glucose metabolism, severe allergies, premenopausal women, recent hormone/immunotherapy recipients, certain comorbidities or substance dependencies.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants' protein needs are determined using a novel, non-invasive approach
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Phenylalanine
Phenylalanine is already approved in European Union, United States for the following indications:
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alberta
Lead Sponsor