Trial Summary
What is the purpose of this trial?
The purpose of this study is to determine if when one eats protein can change how the body uses food for energy. Researchers will also test if eating a high protein breakfast can change one's craving for snack foods.
Research Team
SC
Shanon Casperson, PhD
Principal Investigator
USDA Grand Forks Human Nutrition Research Center
Eligibility Criteria
This trial is for adults with a BMI < 25 or between 30-34.5, who are generally healthy and have not had significant weight changes recently. Women of childbearing age must use birth control and have regular cycles. Participants should eat normal amounts of protein and maintain consistent activity levels.Inclusion Criteria
I can arrange my own travel to the Center.
BMI < 25 kg/m2
Able to understand and sign the informed consent
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Exclusion Criteria
I am on medication that affects my energy levels or appetite.
I do not eat or use animal products.
Have had more than a 10% change in body weight within the past 2 months
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Treatment Details
Interventions
- Even protein (Behavioural Intervention)
- Skewed protein (Behavioural Intervention)
Trial OverviewThe study investigates how the timing of protein intake affects energy metabolism and the desire to snack. It compares two patterns: even distribution of protein throughout the day versus a high-protein breakfast with less at other meals.
Participant Groups
2Treatment groups
Experimental Treatment
Group I: Skewed proteinExperimental Treatment1 Intervention
Menu to provide 90 g of protein per day in a skewed distribution of 10 g at breakfast, 15 g at lunch and 65 g at dinner.
Group II: Even proteinExperimental Treatment1 Intervention
Menu to provide 90 g of protein per day in an even distribution of 30 g at each meal.
Find a Clinic Near You
Who Is Running the Clinical Trial?
USDA Grand Forks Human Nutrition Research Center
Lead Sponsor
Trials
60
Recruited
5,300+
Dr. Julie Hess
USDA Grand Forks Human Nutrition Research Center
Chief Executive Officer since 2024
PhD in Human Nutrition from the University of Minnesota
Dr. Patrizia Cavazzoni
USDA Grand Forks Human Nutrition Research Center
Chief Medical Officer
MD from Harvard Medical School