~4 spots leftby Dec 2026

Protein Intake Patterns for Obesity Management

SC
Overseen byShanon Casperson, PhD
Age: 18 - 65
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: USDA Grand Forks Human Nutrition Research Center
No Placebo Group

Trial Summary

What is the purpose of this trial?

The purpose of this study is to determine if when one eats protein can change how the body uses food for energy. Researchers will also test if eating a high protein breakfast can change one's craving for snack foods.

Research Team

SC

Shanon Casperson, PhD

Principal Investigator

USDA Grand Forks Human Nutrition Research Center

Eligibility Criteria

This trial is for adults with a BMI < 25 or between 30-34.5, who are generally healthy and have not had significant weight changes recently. Women of childbearing age must use birth control and have regular cycles. Participants should eat normal amounts of protein and maintain consistent activity levels.

Inclusion Criteria

I can arrange my own travel to the Center.
BMI < 25 kg/m2
Able to understand and sign the informed consent
See 5 more

Exclusion Criteria

I am on medication that affects my energy levels or appetite.
I do not eat or use animal products.
Have had more than a 10% change in body weight within the past 2 months
See 11 more

Treatment Details

Interventions

  • Even protein (Behavioural Intervention)
  • Skewed protein (Behavioural Intervention)
Trial OverviewThe study investigates how the timing of protein intake affects energy metabolism and the desire to snack. It compares two patterns: even distribution of protein throughout the day versus a high-protein breakfast with less at other meals.
Participant Groups
2Treatment groups
Experimental Treatment
Group I: Skewed proteinExperimental Treatment1 Intervention
Menu to provide 90 g of protein per day in a skewed distribution of 10 g at breakfast, 15 g at lunch and 65 g at dinner.
Group II: Even proteinExperimental Treatment1 Intervention
Menu to provide 90 g of protein per day in an even distribution of 30 g at each meal.

Find a Clinic Near You

Who Is Running the Clinical Trial?

USDA Grand Forks Human Nutrition Research Center

Lead Sponsor

Trials
60
Recruited
5,300+

Dr. Julie Hess

USDA Grand Forks Human Nutrition Research Center

Chief Executive Officer since 2024

PhD in Human Nutrition from the University of Minnesota

Dr. Patrizia Cavazzoni

USDA Grand Forks Human Nutrition Research Center

Chief Medical Officer

MD from Harvard Medical School