Walking Interventions for Parkinson's Disease
(SFYS2 Trial)
Trial Summary
Will I have to stop taking my current medications?
The trial requires that you have been stable on all Parkinson's disease medications for at least 2 months before joining, so you should not stop taking your current medications.
What data supports the effectiveness of the treatment External Cueing Training, Rhythm-Based Walking Interventions, Auditory Rhythmic Stimulation, External Cueing Therapy, Self Cueing Training, Auditory Cueing, Visual Cueing, Rhythm-Based Training, Self-Paced Walking with Rhythmic Cues for Parkinson's Disease?
Research shows that rhythmic auditory cueing, like using a metronome or music, can help people with Parkinson's disease walk better by increasing their speed and stride length. Individualized rhythmic cueing, which adapts to a person's walking pattern, can be a safe and cost-effective way to improve walking in everyday life.12345
Is walking intervention with rhythmic cues safe for humans?
How is the treatment 'Walking Interventions for Parkinson's Disease' different from other treatments for this condition?
What is the purpose of this trial?
The goal of this clinical trial is to compare to rhythm-based walking interventions to enhance gait in people with Parkinson's disease. The main questions it aims to answer are:* How does rhythm-based training influence walking performance?* How does brain activity change following rhythm-based training? Participants will perform walking to music and walking while singing, and will train on the use of these rhythms for 12 weeks. The investigators will compare the effects of training with music to training with singing.
Eligibility Criteria
This trial is for people over 30 with typical Parkinson's disease, stages 2-3, showing walking difficulties but stable on medication. They must be right-handed and able to walk independently for 10 minutes. Excluded are those with severe freezing of gait, significant cognitive issues, unstable health conditions, uncontrolled tremor or dyskinesia, other neurological disorders, cardiac problems affecting safety in the trial or orthopedic issues limiting walking.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants perform rhythm-based walking interventions using self-cueing with singing and external cueing with music, one hour sessions twice weekly for 12 weeks
Follow-up
Participants are monitored for changes in brain activity and gait speed after treatment
Treatment Details
Interventions
- External Cueing Training
- Self Cueing Training
Find a Clinic Near You
Who Is Running the Clinical Trial?
Washington University School of Medicine
Lead Sponsor
National Institutes of Health (NIH)
Collaborator