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Resistance Training +/− Creatine for Prostate Cancer

Q: Are there any opportunities for participation in this experiment currently available?

<p>Indeed. According to clinicaltrials.gov, this study is actively seeking new participants and was initially posted on June 17th 2019 with its last edit occurring January 11th 2022. A total of 85 patients are needed from one location for the trial's completion.</p>

Q: How many participants are being observed in this research endeavor?

<p>Affirmative. Data hosted on the clinicaltrials.gov website reveals that this study, which was initially advertised on June 17th 2019, is still open for recruitment. 85 participants need to be enrolled from 1 medical centre.</p>

Phase < 1

Recruiting

Led By Adriana Coletta

Research Sponsored by University of Utah

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Currently treated with CYP17A1 inhibitors, surgical castration or medical castration with GnRH (gonadotropin-releasing hormone) agonists/antagonists, or androgen receptor blockers. Must have started the current regimen at least 12 weeks prior to enrollment

Metastatic prostate cancer patients who have not met criteria for disease progression on ongoing systemic therapy

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline to 12 weeks post intervention

Awards & highlights

Study Summary

This trial is testing whether resistance training, with or without creatine, can improve body composition and health outcomes in patients with prostate cancer that has spread.

Who is the study for?

This trial is for metastatic prostate cancer patients who can read English, have internet access for video calls, and are willing to do a home-based exercise program. They must be on certain cancer treatments for at least 12 weeks before joining and get their oncologist's okay to start exercising.Check my eligibility

What is being tested?

The study looks at whether resistance training improves body composition and health in prostate cancer patients with fatigue. It compares the effects of doing exercises alone or combined with a creatine supplement over 12 weeks.See study design

What are the potential side effects?

Potential side effects may include muscle cramps or digestive issues from creatine monohydrate, as well as general risks associated with resistance training like muscle soreness or injury.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I've been on hormone therapy for prostate cancer for at least 12 weeks.

Select...

My prostate cancer has spread, but it hasn't gotten worse on my current treatment.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline to 12 weeks post intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline to 12 weeks post intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline to 12 weeks post intervention for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in lean mass

Secondary outcome measures

Change in appendicular lean mass

Change in fat mass

Change in fat-free mass

+11 more

Trial Design

2Treatment groups

Experimental Treatment

Group I: Group II (resistance training, creatine supplementation)Experimental Treatment3 Interventions

Patients complete POWER resistance training program sessions twice weekly over 30-60 minutes each for 12 weeks and receive creatine monohydrate supplementation given orally 4 times daily during week 1, and then QD (once per day) during weeks 2-12.

Group II: Group I (resistance training)Experimental Treatment2 Interventions

Patients complete POWER resistance training program sessions twice weekly over 30-60 minute each for 12 weeks.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Exercise Intervention

2016

Completed Phase 4

~1330

Creatine Monohydrate

2009

Completed Phase 2

~170

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of UtahLead Sponsor

1,099 Previous Clinical Trials

1,778,589 Total Patients Enrolled

8 Trials studying Prostate Cancer

5,349 Patients Enrolled for Prostate Cancer

National Cancer Institute (NCI)NIH

13,665 Previous Clinical Trials

40,925,754 Total Patients Enrolled

561 Trials studying Prostate Cancer

507,095 Patients Enrolled for Prostate Cancer

Adriana ColettaPrincipal InvestigatorHuntsman Cancer Institute/ University of Utah

Media Library

Exercise Intervention (Other) Clinical Trial Eligibility Overview. Trial Name: NCT03987217 — Phase < 1

Prostate Cancer Research Study Groups: Group II (resistance training, creatine supplementation), Group I (resistance training)

Prostate Cancer Clinical Trial 2023: Exercise Intervention Highlights & Side Effects. Trial Name: NCT03987217 — Phase < 1

Exercise Intervention (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03987217 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any opportunities for participation in this experiment currently available?

"Indeed. According to clinicaltrials.gov, this study is actively seeking new participants and was initially posted on June 17th 2019 with its last edit occurring January 11th 2022. A total of 85 patients are needed from one location for the trial's completion."

Answered by AI

How many participants are being observed in this research endeavor?

"Affirmative. Data hosted on the clinicaltrials.gov website reveals that this study, which was initially advertised on June 17th 2019, is still open for recruitment. 85 participants need to be enrolled from 1 medical centre."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Resistance Training +/- Creatine for Metastatic Prostate Cancer Patients

2019. "Resistance Training +/- Creatine for Metastatic Prostate Cancer Patients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03987217.

All > Metastatic Prostate Cancer