Resistance Training +/− Creatine for Prostate Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing if weight lifting can improve health in prostate cancer patients whose cancer has spread. Exercise strengthens muscles and helps them work better.
Will I have to stop taking my current medications?
The trial does not specify that you need to stop taking your current medications. However, you must be on a stable regimen of certain prostate cancer treatments for at least 12 weeks before joining the trial.
Is creatine supplementation and resistance training safe for prostate cancer patients?
Creatine supplementation and resistance training have been shown to be safe in various studies, including those involving older adults and clinical populations. Exercise programs, including resistance training, have been found to improve physical function and quality of life in prostate cancer patients, even those undergoing androgen deprivation therapy.12345
How does the exercise intervention treatment differ from other treatments for prostate cancer?
This treatment is unique because it combines resistance training with or without creatine supplementation to improve muscle strength and physical function in prostate cancer patients undergoing androgen deprivation therapy, which is different from standard drug treatments that primarily focus on hormone levels.35678
What data supports the effectiveness of the treatment Resistance Training +/− Creatine for Prostate Cancer?
Research shows that resistance exercise can improve body composition, physical function, and muscle strength in prostate cancer patients, especially those undergoing androgen deprivation therapy. Additionally, physical activity, including resistance training, may have beneficial effects on prostate cancer outcomes and overall survival.2591011
Who Is on the Research Team?
Adriana Coletta
Principal Investigator
Huntsman Cancer Institute/ University of Utah
Are You a Good Fit for This Trial?
This trial is for metastatic prostate cancer patients who can read English, have internet access for video calls, and are willing to do a home-based exercise program. They must be on certain cancer treatments for at least 12 weeks before joining and get their oncologist's okay to start exercising.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo resistance training with or without creatine supplementation for 12 weeks
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Creatine Monohydrate
- Exercise Intervention
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Utah
Lead Sponsor
National Cancer Institute (NCI)
Collaborator