mHealth Mindfulness Intervention for Postpartum Depression

Age: 18+
Sex: Female
Trial Phase: Phase 3
Sponsor: Kaiser Permanente
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Pivotal Trial (Near Approval)This treatment is in the last trial phase before FDA approval
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores ways to assist pregnant Black and Latina women at risk for postpartum depression, a common mental health issue after childbirth. The study compares two stress reduction programs delivered via a smartphone app, known as the mHealth mindfulness app, to determine which is most effective. Participants use the app daily for 5-20 minutes over six weeks. This trial suits pregnant women under 30 weeks along, who self-identify as Black or Latina, and have experienced moderate depressive symptoms but do not regularly practice stress-reduction techniques like yoga or meditation. As a Phase 3 trial, it represents the final step before FDA approval, offering participants a chance to contribute to important research that could soon benefit many others.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on mindfulness interventions, so it's likely you can continue your medications, but you should confirm with the trial organizers.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that mobile health (mHealth) mindfulness apps can safely help reduce postpartum depression. In previous studies, these apps increased social support and confidence for new mothers. No serious side effects were reported, indicating they are well-tolerated.

For the Stress Reduction Program 'B', studies indicate that mindfulness practices effectively reduce symptoms of postpartum depression. These methods have been used without major safety concerns.

Both treatments focus on mindfulness and stress reduction, which have been shown to be safe for many users. The treatments are digital and self-paced, making them easy to use. While no treatment is risk-free for everyone, past research has generally found these programs to be safe.12345

Why are researchers excited about this trial's treatments?

Researchers are excited about the mHealth mindfulness app for postpartum depression because it offers a convenient, digital approach to managing symptoms, unlike traditional therapies like antidepressants or in-person therapy sessions. This app is designed to be used daily for just 5-20 minutes, making it accessible for new moms who may struggle to find time for lengthy treatments. Additionally, it incorporates stress reduction techniques that are tailored to the unique needs of postpartum women, potentially offering a more personalized treatment experience.

What evidence suggests that this trial's treatments could be effective for postpartum depression?

Research has shown that mobile health (mHealth) mindfulness apps effectively reduce stress, anxiety, and depression symptoms in pregnant and new mothers. These apps assist in managing postpartum depression by offering easy-to-follow stress reduction techniques. Mindfulness activities can lower stress and help new mothers adjust to motherhood.

In this trial, participants will use either the mHealth stress reduction program 'A' app or the stress reduction program 'B' app. Studies have found that similar mindfulness activities in Stress Reduction Program 'B' can greatly reduce depression symptoms during and after pregnancy. These activities help reduce stress and support mothers' mental health. Both programs provide easy-to-access digital solutions to improve mental health for new mothers.16789

Are You a Good Fit for This Trial?

This trial is for pregnant Black and Latina women under 30 weeks gestation, with moderate depression scores (PHQ-9 score of 10-19), receiving prenatal care at KPNC. Participants must own a smartphone or computer with internet access and speak English or Spanish. Women who regularly practice stress reduction or have cognitive impairments, or are deaf cannot participate.

Inclusion Criteria

Gestational age <30 weeks
Owns a smartphone or computer with internet access
Women seeking prenatal care at KPNC
See 2 more

Exclusion Criteria

I am deaf.
Regular (3 times per week or more) stress reduction practice
I have difficulty with thinking or memory.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants use mHealth stress reduction program 'A' or 'B' app 5-20 min daily for 6 weeks

6 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • mHealth mindfulness app
  • Nature sounds
  • Stress reduction program 'A'
  • Stress reduction program 'B'
Trial Overview The study compares two digital self-paced stress reduction programs to see which is more effective in preventing postpartum depression among high-risk pregnant Black and Latina women. It also explores the ease of integrating these programs into a large healthcare system.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment1 Intervention
Group II: Active controlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Kaiser Permanente

Lead Sponsor

Trials
563
Recruited
27,400,000+

Citations

Mindfulness-Based Interventions for Postpartum DepressionMindfulness interventions can alleviate postpartum stress in pregnant women, reduce impulsive behavior, and promote their adjustment to a new life. Based on the ...
The effect of an adapted Mindfulness-Based Stress Reduction ...Results showed a significant and lasting effect on symptoms of perinatal depression in both groups when compared to both active and non-active ...
Results from an effectiveness-implementation evaluation of ...Mothers and Babies 1-on-1 delivered by lay home visitors leads to reductions in perceived stress and depressive symptoms.
Effectiveness of psychosocial education program on ...The psychosocial education program was found to be effective in reducing postnatal depression and stress related to pregnancy and childbirth.
The Efficacy of Be a Mom, a Web-Based Intervention to ...Results: Be a Mom was found to be effective in reducing depressive (intervention group: µΔ=–3.35; P<.001 vs control group: µΔ=–1.48; P<.001) and ...
The effectiveness of mindfulness training on reducing the ...The present research aimed to examine the effectiveness of mindfulness training on reducing the symptoms of postpartum depression. Method. The present quasi- ...
Virtual reality enhanced mindfulness and yoga intervention ...This study demonstrates that integrating VR technology with traditional mindfulness and yoga practices effectively reduces both postpartum depression and ...
The effect of mindfulness-based interventions during ...MBIs can relieve maternal depressive and anxiety symptoms, especially for the prevention of postpartum depression in healthy pregnant women.
A Mindfulness-Based Stress Reduction Psychoeducational ...Beck's (1993) theory of PPD served as the basis for an MBSR psychoeducational program designed to teach women how to reduce stress to improve postpartum.
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