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Social Dance Therapy for Early Alzheimer's Disease
Study Summary
This trial will use partnered, rhythmic rehabilitation, or PRR, as an intervention to target cardiovascular, social, and motor-cognitive domains important to Alzheimer's disease (AD). PRR is a moderate intensity, cognitively-engaging social dance that is safe and results in no injurious falls. This study is a 12-month long Phase II single- blind randomized clinical trial using PRR in 66 patients with early AD.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I have had a stroke within the last three years.I cannot undergo the procedures required in this study.I have been diagnosed with mild memory loss (MCI) according to ADNI standards.I can perform daily activities without significant assistance.You have completed six grades of education or have a good work history.I have mild cognitive impairment that affects my memory.Your Mini-Mental State Exam score should be between 24 and 30, unless you have less than 8 years of education, in which case the study doctor may make an exception.You have not been doing enough exercise each week, as recommended by the US Department of Health and Human Services, and have not been involved in any organized exercise program in the last 3 months.You have mild cognitive impairment that affects your memory.I am taking medication that might affect my thinking or memory.You don't do much exercise and haven't been in a regular exercise program for the past 3 months.I have not been diagnosed with substance use, major depression, or anxiety disorders in the last 6 months.I am currently hospitalized for a sudden illness.I have a diagnosed psychotic disorder.I can walk more than 10 feet on my own without help.I have heart failure that is not well-managed.I do not have severe health issues like uncontrolled high blood pressure, diabetes, or severe arthritis.You have mild memory problems as indicated by a specific score on a memory test.You have been told by someone close to you that you have memory problems or you are worried about your memory.I do not have major neurological conditions like severe head injuries, strokes, or brain tumors.You have trouble remembering things as shown by a test called the Logical Memory subtest.
- Group 1: Group walking (WALK)
- Group 2: Partnered Rhythmic Rehabilitation (PRR)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the current cohort of participants restricted to those aged fifty-five or younger?
"Enrolment in this trial is restricted to those between the ages of 50 and 80. In comparison, there are 23 active clinical trials for minors under 18 and 538 studies recruiting senior citizens older than 65."
What primary goals have been set forth by this research endeavor?
"This evaluation will span from the Baseline to 3 months and 12 months, aiming to gauge an alteration in Acceptability. Secondary objectives include tracking any changes in Spatial 1-Back Test Score (as assessed by EXAMINER), Reverse Corsi Blocks Levels Completed, and Lawton Instrumental Acitivities of Daily Living (IADL) Score."
How many participants is this clinical trial enrolling?
"Confirmed. Clinicaltrials.gov points to the fact that this medical study, which was initiated on October 29th 2019, is currently recruiting patients. 66 participants must be sourced from only 1 site for the trial's completion."
Are there still opportunities for participants in this experiment?
"Affirmative. Clinicaltrials.gov reports that this clinical trial, which first went public on October 29th 2019 is still searching for participants to join the study. This medical undertaking requires 66 patients to be recruited from a single site."
Who is eligible to enroll in this research project?
"This clinical trial seeks 66 individuals between 50 and 80 years of age who have been diagnosed with Alzheimer's disease. Participants must also meet the following criteria: evidence of memory impairment, an MMSE score between 24 - 30, CDR= 0.5, preserved general functioning ability (including walking), 6+ grades of education or suitable work experience to exclude intellectual disabilities, less than 150 minutes/week moderate intensity exercise or 75 minutes/week vigorous intensity activity without being enrolled in a structured program within 3 months prior and no hospitalizations within the last 2 months."
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