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Behavioural Intervention

Non-invasive Brain Stimulation for Gait Instability

N/A

Waitlist Available

Led By On-Yee Lo, Ph.D.

Research Sponsored by Hebrew SeniorLife

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Aged 65 and above

Elevated gait variability as defined by a coefficient of variation (CoV) about average stride time larger and equal to 0.025 during straight-line walking at preferred speed

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, immediate post-intervention, 1 month follow up

Awards & highlights

Study Summary

This trial seeks to improve walking and cognitive performance in older adults with a non-invasive brain stimulation technique.

Who is the study for?

This trial is for adults aged 65 or older who can walk on their own and have a high variability in their walking pattern, which may increase the risk of falls. They must speak English and be able to walk continuously for at least one minute. People with severe pain affecting walking, recent serious illnesses, significant cognitive impairment, certain neurological disorders, uncontrolled heart conditions, active cancer treatment, psychiatric issues or those taking sedating medications are not eligible.Check my eligibility

What is being tested?

The StimGait trial is testing non-invasive brain stimulation called tDCS to see if it can improve walking steadiness in older adults. Participants will receive either the real tDCS treatment or a sham (fake) version without knowing which one they're getting. The study aims to see how this affects brain activity related to movement and attention.See study design

What are the potential side effects?

tDCS is generally considered safe but might cause mild side effects like itching or tingling under the electrode during stimulation, headache after treatment sessions, fatigue or nausea. Serious side effects are rare.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am 65 years old or older.

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My walking pattern is irregular, with stride times varying significantly.

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I can walk on my own for at least 1 minute without stopping.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, immediate post-intervention, 1 month follow up

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, immediate post-intervention, 1 month follow up

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, immediate post-intervention, 1 month follow up for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Gait variability

Secondary outcome measures

Accuracy (d prime) on the gradual onset continuous performance task (gradCPT)

Dual-task gait performance

Gait speed

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: tDCS interventionExperimental Treatment1 Intervention

Ten, once-daily, 20-min sessions of tDCS will be provided over two consecutive weeks.

Group II: Sham and then tDCSPlacebo Group2 Interventions

Five, once-daily, 20-min sessions of sham in week one followed by five, once-daily, 20-min sessions of tDCS in week two.

0 / 3Eligibility criteria met

Find a Location

Who is running the clinical trial?

Hebrew SeniorLifeLead Sponsor

45 Previous Clinical Trials

270,526 Total Patients Enrolled

National Institute on Aging (NIA)NIH

1,669 Previous Clinical Trials

28,005,084 Total Patients Enrolled

On-Yee Lo, Ph.D.Principal InvestigatorHinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment still open for this research program?

"Confirmed, the data on clinicaltrials.gov indicates that this particular medical trial is not recruiting at present. Originally uploaded to the site on November 1st 2023 and last updated a little over 8 months ago, there are 129 alternate trials actively seeking participants now."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Non-invasive Brain Stimulation to Improve Unsteady Gait in Older Adults (StimGait)

2023. "Non-invasive Brain Stimulation to Improve Unsteady Gait in Older Adults (StimGait)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06008431.