Full Body Radiographs for Skeletal Structure Analysis
Trial Summary
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment EOS imaging system?
Is the EOS imaging system safe for humans?
How does the EOS imaging system treatment differ from other treatments for skeletal structure analysis?
The EOS imaging system is unique because it provides full-body 2D and 3D images with a very low radiation dose, capturing both front and side views simultaneously, which is not possible with conventional X-rays. This allows for a comprehensive analysis of the skeletal structure, particularly useful for conditions like scoliosis and osteoarthritis, while minimizing radiation exposure.12345
What is the purpose of this trial?
A study of the skeletal structure and how the structure changes over time. The aim of the study is to evaluate the skeleton in 10 year increments to determine an understanding of the normal skeleton as a person ages. By using x-ray analysis, a new low dose x-ray system (EOS) can be used to evaluate the whole body to see changes in the bone structure over time. Subjects will be asked to undertake one x-ray analysis of their whole body skeletal structure. There will be 25 male and 25 female subjects per decade. The averaging of the measured skeletal parameters will provide information on changes over time generating a standardized expectation of general changes in skeletal structure as participants age.
Research Team
Christopher Kleck, MD
Principal Investigator
University of Colorado, Denver
Eligibility Criteria
This trial is for men and women aged 21-85 with no history of spine surgery. It's not suitable for those who've had knee replacements, severe joint arthritis, spinal trauma or surgery, certain disability scores, inflammatory disorders, significant past fractures or surgeries on the pelvis or lower limbs, are pregnant, have a history of cancer or a BMI over 37.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Imaging
Participants undergo a single EOS biplanar x-ray imaging session to analyze whole body skeletal structure
Follow-up
Participants' radiographic data is analyzed for age-related changes in skeletal structure
Treatment Details
Interventions
- EOS imaging
EOS imaging is already approved in European Union, United States, Canada for the following indications:
- Orthopedic assessments
- Scoliosis monitoring
- Musculoskeletal disorders
- Orthopedic assessments
- Scoliosis monitoring
- Musculoskeletal disorders
- Hip and knee replacement surgeries
- Orthopedic assessments
- Scoliosis monitoring
- Musculoskeletal disorders
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Colorado, Denver
Lead Sponsor