This trial is evaluating whether CASE will improve 8 primary outcomes and 1 secondary outcome in patients with Return to Sport. Measurement will happen over the course of through study completion, an average of 1.5 hours.
This trial requires 125 total participants across 1 different treatment group
This trial involves a single treatment. CASE is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"In 2003, 5.5 million American adults participated in some way in physically demanding varsity sports. Despite the enormous benefits of activity in general to a person's quality of life, it remains a challenge for health professionals to identify those who should be encouraged to participate in varsity athletics." - Anonymous Online Contributor
"Most participants with shoulder or rotator cuff tears can return to some degree of sport regardless of their functional ability to return preinjury levels, with the exception of those experiencing pain during the activity and those with postoperative shoulder instability." - Anonymous Online Contributor
"Many cases of overuse injuries and overtraining are related to previous history of injury or overtraining, respectively. These injuries can be prevented and the overtraining is curable." - Anonymous Online Contributor
"For patients undergoing ACL reconstruction the rehabilitation process may be complicated by the need to return to sport safely and to a level at which no knee disability is recorded. In order to limit the possible rehabilitation complications that may result from return to sport we recommend careful consideration be given to the risks and benefits to both the knee and the patient, before a patient can return to sport following ACL reconstruction." - Anonymous Online Contributor
"Recent findings suggests that there are risk factors for return to sport that were not identified previously, for example, age at onset of the injuries. The need for further education was emphasised with the potential risk to future professional athletes in the event of an ACL injury and the possible impact on knee joint health." - Anonymous Online Contributor
"The return to sport depends on the level of sports activity, training level, age and the severity of concussion. It can be difficult to understand this phenomenon if doctors rely on the standard physical examination and history. In addition, there is an absence of consensus for an international definition of concussion. Recent findings of this study showed that clinical signs of returning to sport is affected by the level and age of sports and the concussion severity. However, there is no consensus for the definition of concussion." - Anonymous Online Contributor
"Patients who had returned to an active level of functioning have an acceptable quality of life. However it would be anticipated if they had recovered from their injury or from their illness." - Anonymous Online Contributor
"The impact of return to sport is significant as shown by an increase in functional status and high satisfaction of patients with return to sport. The effect of return to sport on pain seems to be modest and this should be further confirmed as return to sport may help maintain gains in functional status in patients with knee OA." - Anonymous Online Contributor
"Recent findings of this evidence-based review suggest that a combination of strategies have the best short-term outcomes with respect to sportsmanship, return to play and physical activity following sport injury." - Anonymous Online Contributor
"There were more common side effects of case than expected; some were very common, but some were rare. These outcomes may be due to case's high prevalence of common side-effects." - Anonymous Online Contributor
"A new therapeutic application is based on the fact that some muscle and muscle-derived cells and proteins, like collagen, are present in atherosclerotic plaque. These proteins are released into the circulation from atherosclerotic tissue and could be used as biomarkers for detecting the presence of plaque. We have recently demonstrated that cell-mediated release of CGRP from activated astrocytes induced significant plaque destabilization. Findings from a recent study may be used in the diagnosis of plaque stability by detecting circulating proteins, with respect to CGRP, that are released from activated astrocytes. Furthermore, CGRP released from activated astrocytes may contribute to the pathogenesis or progression of atherosclerosis or other inflammatory neurodegenerative diseases." - Anonymous Online Contributor
"This is the first published study examining the use of clinical trials for sports medicine. It shows that not only is clinical evidence relevant to sports medicine, but that evidence is used as a reference by some of these clinical trials in terms of eligibility procedures. Clinical studies are an important reference for medical providers to use when considering treatments of athletes." - Anonymous Online Contributor