This trial is evaluating whether Parent Interactive Text Message - Benefits Approach will improve 2 primary outcomes, 1 secondary outcome, and 1 other outcome in patients with HPV. Measurement will happen over the course of 12 months.
This trial requires 21110 total participants across 9 different treatment groups
This trial involves 9 different treatments. Parent Interactive Text Message - Benefits Approach is the primary treatment being studied. Participants will be divided into 8 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"The most common symptoms are vaginal discharge and changes in vaginal discharge can be indicative of HSV-2. Other symptoms are usually more specific to particular HSV types. For example, genital wart is seen in HSV-1. HSV can be diagnosed through direct visualization; however, it can be difficult for untrained individuals when there are no visible lesions. For example, it might be difficult to determine the presence or absence of HSV-2 without direct visualization of the anus or urethra, which is the only place from which the virus is transmitted. The most common symptoms are fatigue, aching, and pain. However, HPV-like symptoms are also typical of HSV." - Anonymous Online Contributor
"HPV is an oncogenic virus that is present in the vast majority of [cervical cancer](https://www.withpower.com/clinical-trials/cervical-cancer)s. This virus most likely infects by entering the cervical epithelium. HPV can occur in any age but typically presents in women from ages 15 to 45. The virus is transmitted through sexual activity and causes lesions that eventually become cancerous. These lesions occur primarily in the vagina, although some occur elsewhere on the body. HPV can cause cancers of the cervix, throat, larynx (squamous cell carcinoma), anogenital (vaginal, vulvar, penile), nasal and penis ( penile squamous cell carcinoma) regions, in infants, in immunocompromised and HIV-positive individuals." - Anonymous Online Contributor
"Different subtypes of HPV have different clinical presentations, so clinical trials often test only the major forms (e.-g., warts). Treatments are often specific to HPV types, such as vaccine-based treatment for infections by HPV-16 and HPV-18." - Anonymous Online Contributor
"HPV-associated cervical cancer, vaginal intraepithelial neoplasia, vulvar intraepithelial neoplasia, vulvar intraepithelial neoplasia, papilloma of uncertain malignant potential and vulvar squamous cell carcinoma of the vulva are related to HPV infection during pregnancy. However, the role of spontaneous HPV transmission after birth, and other forms of HPV infection, remains unclear." - Anonymous Online Contributor
"The incidence of CIN in black women is higher than in white women; these differences are largely explained by high HPV infection rates. Women in the highest-risk groups can benefit from targeted vaccination, as can women with CIN or ASC-US." - Anonymous Online Contributor
"Currently HPV is considered a 'life-threatening' illness, and some of the known viral types cause a higher risk of developing cervical cancer than others. Therefore, HPV is considered a life-threatening illness that depends on management of high-risk HPV types in order to prevent cervical cancer. However, HPV can be cured, if the HPV infection is effectively treated at the early stages of infection. HPV has a cure rate of less than 10% if all high-risk HPV types are treated early and cured, unless the infection is recurrent." - Anonymous Online Contributor
"There is not a single primary cause for high-risk HPV. There are many hypotheses, and most likely they all coexist. The current debate is between the idea that all high-risk HPV in the past was acquired in one event, and the idea that multiple exposures to different risk factors result in different variants. The concept of multiple exposures is generally accepted by many. It is interesting that a vaccine using HPV types from the past has very low efficacy. Researchers should continue to investigate why the vaccine isn't as effective as other vaccines." - Anonymous Online Contributor
"The brief intervention was efficacious, with statistically significant (p = 0.01) reduced HPV detection and greater reductions in the percentage of patients whose primary provider was reported as not providing or not discussing HPV testing. There was no difference between the intervention and control providers in receipt and discussions of other HPV-related vaccines or in receipt of Pap tests or other clinical services. Data from a recent study suggest that brief provider instructions and educational materials can reduce the numbers of adolescents receiving unnecessary HPV services. To improve adolescent uptake of HPV vaccine and decrease their rates of HPV-induced cancer in the future, implementing a program similar to the one undertaken in this study may be a helpful strategy." - Anonymous Online Contributor
"The average age of incidence of the HPV genotypes involved in the disease is 6 years old (range: 1 week to 23 years old) whereas the age at which incidence decreases significantly is 18 years (range: 2 weeks to 47 years old). The probability of HR-HPV infection decreases significantly from adolescence (13-19 years old) to adulthood (21-24 years old)." - Anonymous Online Contributor
"In this sample of adolescents, brief provider training with more than 4 modules, incorporating the core topics, was associated with greater knowledge and self-reported adherence. The content and duration of provider training are important for the success of short-term self-management education. The benefits approach is feasible as an adjunct to standard care, with a reduction in costs. The authors contend that their approach may be an effective short-term preventive therapy of adolescents at risk of STD." - Anonymous Online Contributor
"The benefits approach is an effective and time-saving way of ensuring provider compliance with patient safety recommendations during provider training. Additional study may determine if our approach results in fewer negative side effects and more provider compliance with the PSI recommendation." - Anonymous Online Contributor
"Based on these survey results, brief training of general internal medicine residents was beneficial for most surveyed learners. However, there exists potential for shortening training to four weeks." - Anonymous Online Contributor