Provider Training + Interactive Texting for HPV Vaccination

(Text&Talk Trial)

Not currently recruiting at 1 trial location

Overseen By Marta D Hansen, MBA

Age: Any Age

Sex: Any

Trial Phase: Academic

Sponsor: University of Florida

Disqualifiers: Out of age range, No cell phone, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests two methods to increase HPV vaccination rates among 11- to 12-year-olds in Florida. It examines the effectiveness of text messages for parents and training sessions for healthcare providers in promoting vaccinations. The trial includes different groups: some receive training, some receive text messages, and some receive both or neither. It suits parents with children aged 10 to 12 who have not yet received adolescent vaccines and visit participating clinics. As an unphased trial, it provides a unique opportunity to contribute to research that could enhance public health strategies.

Do I have to stop taking my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on increasing HPV vaccination rates, so it's unlikely to require changes to your medication.

What prior data suggests that these interventions are safe for increasing HPV vaccination rates?

Research has shown that these methods have been well-tolerated in past studies. Studies indicate that training healthcare providers in better communication skills can increase HPV vaccination rates without known side effects. Specifically, one study found that this training boosted vaccination rates by about 5.2%.

Research also suggests that text message reminders sent to parents are safe. Studies have found these reminders effective in improving timely HPV vaccination rates, with no reports of negative reactions.

Overall, both provider training and text message reminders have successfully supported HPV vaccination efforts in the past and are generally considered safe for participants. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores innovative ways to boost HPV vaccination rates through provider training and interactive texting with parents. Unlike traditional methods that rely solely on in-person education, this approach uses brief training sessions for clinicians, focusing on either the benefits of the vaccine or a bundled message approach. Additionally, it engages parents with interactive text messages, which could make information more accessible and timely. This trial aims to find out if these strategies can effectively increase vaccination rates, which is crucial for preventing HPV-related diseases. By combining digital communication with targeted clinician training, the trial could pave the way for more effective vaccination campaigns in the future.

What evidence suggests that this trial's interventions could be effective for increasing HPV vaccination rates among 11- to 12-year-olds?

Research shows that training doctors and sending text messages to parents can increase HPV vaccination rates. In this trial, some participants will experience a combination of these methods. Studies have found that when doctors improve their communication skills, vaccination rates rise by about 5.2%. Automated text reminders have also successfully encouraged timely HPV vaccinations. Messages with clear facts make parents more willing to vaccinate their children. Combining these methods has improved vaccination rates and boosted doctors' confidence. Overall, these strategies effectively increase the number of children vaccinated against HPV. ^{3 5 6 7 8}

Who Is on the Research Team?

Stephanie Staras, PhD

Principal Investigator

University of Florida

Are You a Good Fit for This Trial?

This trial is for parents of 10- to 12-year-olds who haven't had the HPV vaccine and visit participating Florida clinics. It's also for providers giving primary care to this age group at these clinics. Adolescents outside this age range, those opted-out of texts, or without a cell number on file can't join.

Inclusion Criteria

I am a primary care provider for 11 to 12-year-olds at a participating clinic.

I am the parent of a teenager who meets the trial criteria.

I am between 10 and 12 years old and have visited a clinic in the last two years.

Exclusion Criteria

My guardians or I are willing to consent to participation.

I am not an adolescent.

I previously chose not to receive text messages.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention Delivery

Clinicians receive training and parents receive text messages as part of the intervention

12 months

Training sessions via Zoom, text messages sent periodically

Follow-up

Participants are monitored for HPV vaccination initiation and up-to-date status

24 months

What Are the Treatments Tested in This Trial?

Interventions

• Brief Provider Training - Benefits Approach
• Brief Provider Training - Bundled Approach
• Parent Interactive Text Message - Benefits Approach
• Parent Interactive Text Message - Bundled Approach

Trial Overview The study tests two methods to increase HPV vaccination rates: one sends educational text messages to parents, and the other provides brief training to clinicians. The goal is to see if these approaches encourage vaccinations in 11-12 year olds.

How Is the Trial Designed?

Group I: Deferred-clinician training and bundled text messages Experimental Treatment 1 Intervention

Clinicians will receive training after the study and parents will receive bundled text messages.

Group II: Deferred-clinician training and benefits text messages Experimental Treatment 1 Intervention

Clinicians will receive training after the study and parents will receive benefits text messages.

Group III: Bundled clinician training and no text messages Experimental Treatment 1 Intervention

Clinicians will receive bundled approach training and parents will not receive any intervention text messages.

Group IV: Bundled clinician training and bundled text messages Experimental Treatment 2 Interventions

Clinicians will receive bundled approach training and parents will receive bundled text messages.

Group V: Bundled clinician training and benefits text messages Experimental Treatment 2 Interventions

Clinicians will receive bundled approach training and parents will receive benefits text messages.

Group VI: Benefits clinician training and no text messages Experimental Treatment 1 Intervention

Clinicians will receive benefits approach training and parents will not receive any intervention text messages.

Group VII: Benefits clinician training and bundled text messages Experimental Treatment 2 Interventions

Clinicians will receive benefits approach training and parents will receive bundled text messages.

Group VIII: Benefits clinician training and benefits text messages Experimental Treatment 2 Interventions

Clinicians will receive benefits approach training and parents will receive benefits text messages.

Group IX: Deferred-clinician training and no text messages Active Control 1 Intervention

Clinicians will receive training after the study and parents will not receive intervention text messages.

Who Is Running the Clinical Trial?

University of Florida

Lead Sponsor

Trials

1,428

Recruited

987,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11209355/

Clinician Communication Training to Increase Human ... Our findings indicated that clinician communication training could enhance vaccination uptake rates by an average of 5.2%.

2. sciencedirect.com sciencedirect.com/science/article/pii/S009174352500091X

A scoping review of pediatric healthcare provider HPV ... A brief provider training video improves comfort with recommending the human papillomavirus vaccine. Clin. Pediatr. (Phila), 58 (2019), pp. 17-23. Crossref ...

3. publications.aap.org publications.aap.org/pediatrics/article/150/2/e2021052351/188506/Coaching-and-Communication-Training-for-HPV

Coaching and Communication Training for HPV Vaccination Combining QI coaching with remote provider communication training yielded more consistent improvements in HPV vaccination uptake than QI ...

4. clinicaltrials.gov clinicaltrials.gov/study/NCT02377843?cond=Human%20papillomavirus&viewType=Table&rank=10

Making Effective Human Papillomavirus (HPV) Vaccine ... This study will evaluate the effectiveness of two communication trainings to increase HPV vaccination coverage among adolescent patients. We will compare HPV ...

5. trialx.com trialx.com/clinical-trials/listings/278520/text-and-talk-a-multi-level-intervention-to-increase-provider-hpv-vaccine-recommendation-effectiveness/?&radius=50&query=human%20papillomavirus%20vaccine&smt=true

A Multi-level Intervention to Increase Provider HPV Vaccine ... This study will test the effectiveness of two interventions (parent-targeted text messages and a brief clinician-targeted training) at ...

6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC8310215/

A Systematic Review of Interventions to Improve HPV ... Our review found that various evaluated interventions have improved HPV vaccination coverage, including narrative education, outreach plus reminders, reminders ...

7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11056302/

Clinician Prompts for Human Papillomavirus Vaccination We assessed the impact of an online intervention using clinician prompts for human papillomavirus (HPV) vaccination with a cluster randomized controlled trial.

8. mdpi.com mdpi.com/2076-393X/12/6/611

Clinician Communication Training to Increase Human ... Our findings indicated that clinician communication training could enhance vaccination uptake rates by an average of 5.2%.