This trial is evaluating whether Pulmonary Valve Replacement Surgery will improve 4 primary outcomes and 25 secondary outcomes in patients with Heart Diseases. Measurement will happen over the course of 30 days.
This trial requires 15 total participants across 1 different treatment group
This trial involves a single treatment. Pulmonary Valve Replacement Surgery is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
"After reviewing the cases of the 9 individuals with congential heart defects reported to the Western Australia State Department of Health in 1992-1994 we find that 4 of the individuals died during the first 6 months of life. None of the individuals who succumbed to congential heart defects were subjected to a heart transplant. We conclude that survivors of congential heart defects are likely to suffer multiple sequelae rather than cure. The role of the paediatric cardiologist in such groups is uncertain but it might be that they play a role in deciding on medical management as well as in educating parents on the prognostic factors as well as the benefits and risks of treatment." - Anonymous Online Contributor
"Signs typically include asymmetry of the face with asymmetrical or unequal nostrils, enlarged tongue with an upward and downward bulge, and the presence of a fistula. Other signs of heart defects, congenital may be present, but are more subtle. The most common heart defect, cleft palate, may be not noticed at the time of birth, leading to delay for diagnosis. The signs of cleft lip with or without cleft palate may also be present." - Anonymous Online Contributor
"heart defects can have many reasons including chromosomal anomalies, or a mixture of both genetic and environmental factors. A number of diseases can cause heart defects like: Down Syndrome, trisomic trisomy mosaicism, Turner syndrome and Prader-Willi syndrome. Congenital heart defects can also be caused by defects in the embryonic development of the heart. Many defects can cause pulmonary hypertension and are often associated with genetic conditions such as Noonan/Patau complex syndrome. Congenital heart defects can also have multiple causes, which include syndromic heart anomalies, genetic syndromes or single-gene defects." - Anonymous Online Contributor
"In comparison to typical populations, heart defects, congenital are more often encountered in a large proportion of patients with schizophrenia. The frequency of heart defects, congenital is 1.8 times higher in patients with schizophrenia." - Anonymous Online Contributor
"Current treatment options for some congenital heart defects are tailored to patient-specific requirements. Commonly pursued interventions include surgery, catheter-based therapies, and heart failure therapies. In a minority of patients, heart valve and/or outflow tract defects may not be surgically repairable and may be managed by alternative therapy(s) such as catheter-based therapies or medications." - Anonymous Online Contributor
"More than 80,000 children in the United States are born with a heart defect. This makes it the most common birth defect in the United States. Congenital heart defects are most prevalent in males. theme:
Cultural practices can affect the rates in which individuals with disabilities or long-term conditions die. For example, people in nations in which the law places greater importance on a child's education may be more likely to die in later life if educated through their disability.\n\nThere are many ways in which individuals may have their lifespan shortened as a result of disability." - Anonymous Online Contributor
"Heart or thoracic abnormalities like CHD are associated with several other comorbidities which are serious enough to warrant attention and treatment, but most importantly with [premature death], especially if not detected in childhood." - Anonymous Online Contributor
"The pulmonary valve replacement results in significant reductions in blood pressure after the procedure in an effort to help the heart pump blood to areas of increased peripheral vascular resistance. The most common side effect of surgery is the formation of a valve prolapse where a portion of an old or a faulty cardiac valve is expelled from the heart. This can be corrected by use of the surgeon's heart to plug this hole. Other complications may arise from complications that occur during surgery. The patient undergoes the procedure as a complete unit and is not removed from the operation room until the surgeon has finished completing the heart procedure. The amount of time spent in the operating room depends on the actual case load present." - Anonymous Online Contributor
"As of 2000, the average age that someone will develop heart defects, congenital was reported as 8.0-7.5 year of age. A recent report states the average age as 2.5 year of age. This is reassuring because this is a critical period where heart defects may occur. When there is a family member with a heart defect, it is most likely to appear in later age. People should be checked and watched for any sign or symptoms. To find out if you have a family member who has had heart defects, look [power (power.com) to find out." - Anonymous Online Contributor
"Pulmonary valve replacement surgery is a safe and effective procedure. It is a durable treatment for pulmonary stenosis. In symptomatic patients, the main indications for surgical intervention of symptomatic pulmonary regurgitation are worsening heart failure or exercise intolerance. In patients requiring concomitant repair of atrial septal defects, valve prolapse, and/or residual pulmonary stenosis, pulmonary valve replacement was more likely to be performed." - Anonymous Online Contributor
"This article is an update for congenital heart defects. There is no single or standardized treatment for heart defects, and therapy depends on the complexity of the problem, the patient's presentation, the surgeon's expertise, and the general medical condition. In this article, we review heart defects and the treatment procedures used to help children with defects. Also, we update a list of surgeries that may be used for heart defects." - Anonymous Online Contributor
"PVR was typically used in combination with other treatments in the study population in our experience. However, randomized, controlled, multicenter trials have shown that PVR can be administered alone if the cardiac valve function is maintained to a statistically equivalent condition. In addition, when performing other concomitant pulmonary artery procedures in a patient with a PVR, careful consideration should be given to the possible worsening of ventricular function." - Anonymous Online Contributor