Aerobic Exercise Timing for Obesity
(TANDEM Trial)
Trial Summary
What is the purpose of this trial?
This study plans to learn more about metabolic responses to aerobic exercise at different times of the day (morning or evening) under fasting versus fed conditions.
Will I have to stop taking my current medications?
The trial requires that you do not regularly use medications that significantly impact appetite, weight, energy metabolism, heart rate, or sleep. If you are on such medications, you may need to stop taking them to participate.
What data supports the effectiveness of the treatment Aerobic Exercise, Physical Activity, Cardiovascular Exercise, Fitness Training for obesity?
Research shows that adding aerobic exercise to a weight management program can significantly improve fitness, body measurements, and psychological well-being in people with obesity. Studies suggest that engaging in more than 150 minutes of moderate-intensity aerobic activity per week can help prevent weight gain and improve overall health.12345
Is aerobic exercise safe for people with obesity?
How does the timing of aerobic exercise differ as a treatment for obesity?
Research Team
Seth Creasy, PhD
Principal Investigator
University of Colorado, Denver
Eligibility Criteria
This trial is for adults who are generally healthy but living with obesity. Participants should be interested in how aerobic exercise affects metabolism under different conditions, such as fasting or after eating.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants engage in aerobic exercise under different conditions (fasted/fed, AM/PM) to study metabolic responses
Follow-up
Participants are monitored for metabolic changes and energy expenditure after exercise sessions
Treatment Details
Interventions
- Aerobic Exercise
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Colorado, Denver
Lead Sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator