Jaspr App for Suicide Prevention

(Jaspr-PartB Trial)

Recruiting at 3 trial locations

Overseen By Mhd B Rahmoun, MD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of Massachusetts, Worcester

Disqualifiers: Cognitive, Emotional incapability

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

27908 Participants Needed

Trial Summary

What is the purpose of this trial?

This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with productive time in the Emergency Departments (EDs). The EBPs satisfy several key performance elements for systems adopting Zero Suicide. A Complementary Randomized Controlled Trial and Real-World Study for Efficacy, Effectiveness, and Implementation Study Design (CREID) will be used

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment Jaspr Health for suicide prevention?

Research shows that mobile apps, like Jaspr Health, can effectively deliver evidence-based practices for suicide prevention, such as safety planning and self-monitoring, which are known to reduce the risk of suicidal behavior. ^{1 2 3 4 5}

How is the Jaspr App treatment for suicide prevention different from other treatments?

The Jaspr App is unique because it is a tablet-based application designed for use directly by patients in emergency departments, delivering four evidence-based practices for suicide prevention. Unlike traditional treatments that require significant time and personnel, this app provides immediate, accessible support tailored to the patient's needs, making it a novel approach in emergency settings. ^{1 2 6 7 8}

Research Team

Edwin D Boudreaux, PhD

Principal Investigator

UMass Chan Medical School

Eligibility Criteria

This trial is for individuals in emergency departments who have engaged in self-harm or are experiencing suicidal thoughts or attempts. Participants must be willing to use the Jaspr Health app during their ED visit.

Inclusion Criteria

Must test positive for suicide risk on screener

Must be able to read English, or have a proxy available to read and enter questions

Exclusion Criteria

I am unable to interact with Jaspr due to cognitive or emotional reasons.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Retrospective Enhanced Treatment as Usual (ETAU)

A retrospective phase comprising 12 months of index ED visits with a 12 month follow-up window

12 months

Implementation/Intervention

Implementation of Jaspr in EDs, comprising 18 months of index ED visits with a 12 month follow-up window

18 months

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 months

Treatment Details

Interventions

• Jaspr Health

Trial Overview The study tests the Jaspr Health app, designed to make waiting time in emergency departments more productive by providing suicide prevention strategies and support through evidence-based practices.

Participant Groups

Group I: Jaspr Implementation Group Experimental Treatment 1 Intervention

This group will receive the enhanced treatment as usual (ETAU) provided as part of routine clinical care at the participating EDs. They will also be considered by their treating team for administration of Jaspr. Jaspr administers a Suicide Status Interview (SSI), Safety Planning, and Lethal means counseling, and allows open access to the Jaspr resource library. They can sign up to receive Jaspr at Home mobile app. Electronic Health Records (EHR) will be used to assess the outcomes in the 12 months following the index visit.

Group II: Enhanced Treatment as Usual (ETAU) Historical Control Group Active Control 1 Intervention

Enhanced Treatment As Usual (ETAU) Historical Control is defined as the treatment provided as part of routine clinical care in the participating EDs during a period of time when Jaspr was not being implemented.

Who Is Running the Clinical Trial?

University of Massachusetts, Worcester

Lead Sponsor

Trials

372

Recruited

998,000+

University of Colorado, Denver

Collaborator

Trials

1,842

Recruited

3,028,000+

Worcester Polytechnic Institute

Collaborator

Trials

19

Recruited

30,000+

Ohio State University

Collaborator

Trials

891

Recruited

2,659,000+

Evidence-Based Practice Institute, Seattle, WA

Industry Sponsor

Trials

9

Recruited

29,800+

National Institute of Mental Health (NIMH)

Collaborator

Trials

3,007

Recruited

2,852,000+

Findings from Research

The Jaspr Health app was found to be feasible and acceptable for use among acutely suicidal patients in emergency departments, with high user satisfaction and no adverse events reported during the study.

Participants using the app experienced significant improvements, including increased access to evidence-based suicide prevention interventions and reductions in distress and agitation, compared to those receiving standard care.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Using a Tablet-Based App to Deliver Evidence-Based Practices for Suicidal Patients in the Emergency Department: Pilot Randomized Controlled Trial. Dimeff, LA., Jobes, DA., Koerner, K., et al.[2023]

The CASPAR study aims to evaluate the feasibility of using mobile health applications for safety planning and daily self-monitoring in 80 patients with major depressive disorder or dysthymia at risk for suicidal behavior.

By integrating mobile safety plans and symptom tracking into routine care, the study seeks to enhance understanding of the suicidal process and improve treatment outcomes for high-risk patients.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Smartphone-based safety planning and self-monitoring for suicidal patients: Rationale and study protocol of the CASPAR (Continuous Assessment for Suicide Prevention And Research) study. Nuij, C., van Ballegooijen, W., Ruwaard, J., et al.[2023]

The WellPATH app, used during a 12-week psychotherapy intervention for middle-aged and older adults after suicide-related hospitalization, showed high feasibility and acceptability, with participants and therapists expressing satisfaction with the app.

Case studies indicated that using WellPATH helped patients reduce negative emotions and improve their ability to regulate emotions, suggesting potential benefits for suicide prevention.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

An Emotion Regulation Tablet App for Middle-Aged and Older Adults at High Suicide Risk: Feasibility, Acceptability, and Two Case Studies. Kiosses, DN., Monkovic, J., Stern, A., et al.[2022]

The pilot study involving 66 adolescents showed that the ASAP intervention, which includes a smartphone app for emotion regulation, did not significantly reduce suicide attempts post-discharge, but indicated a trend towards fewer attempts (16% vs. 31%).

Participants with a history of previous suicide attempts may benefit more from the ASAP intervention, suggesting that this program could be tailored for those at higher risk, and overall, the intervention and app were well-received by users.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

As Safe as Possible (ASAP): A Brief App-Supported Inpatient Intervention to Prevent Postdischarge Suicidal Behavior in Hospitalized, Suicidal Adolescents. Kennard, BD., Goldstein, T., Foxwell, AA., et al.[2023]

The mobile app developed as part of the SERO suicide prevention program aims to reduce suicides and suicide attempts by enhancing self-management for individuals at risk, incorporating strategies like safety planning and mood tracking.

The app's design was informed by collaboration among health professionals, individuals at risk, and their families, ensuring it addresses real needs and integrates essential suicide prevention strategies effectively.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

SERO - A New Mobile App for Suicide Prevention. Meier, L., Gurtner, C., Nuessli, S., et al.[2022]

The suicide rate in the U.S. has remained largely unchanged for the past century, highlighting the urgent need for innovative prevention strategies.

Just-In-Time Adaptive Interventions (JITAIs) using smartphones and wearables could provide timely, personalized support for individuals experiencing suicidal thoughts, potentially improving the effectiveness of suicide prevention efforts.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Just-in-Time Adaptive Interventions for Suicide Prevention: Promise, Challenges, and Future Directions. Coppersmith, DDL., Dempsey, W., Kleiman, EM., et al.[2023]

References

1. Canada pubmed.ncbi.nlm.nih.gov

Using a Tablet-Based App to Deliver Evidence-Based Practices for Suicidal Patients in the Emergency Department: Pilot Randomized Controlled Trial. [2023]

2. Netherlands pubmed.ncbi.nlm.nih.gov

Smartphone-based safety planning and self-monitoring for suicidal patients: Rationale and study protocol of the CASPAR (Continuous Assessment for Suicide Prevention And Research) study. [2023]

3. England pubmed.ncbi.nlm.nih.gov

An Emotion Regulation Tablet App for Middle-Aged and Older Adults at High Suicide Risk: Feasibility, Acceptability, and Two Case Studies. [2022]

4. United States pubmed.ncbi.nlm.nih.gov

As Safe as Possible (ASAP): A Brief App-Supported Inpatient Intervention to Prevent Postdischarge Suicidal Behavior in Hospitalized, Suicidal Adolescents. [2023]

5. Netherlands pubmed.ncbi.nlm.nih.gov

SERO - A New Mobile App for Suicide Prevention. [2022]

6. United States pubmed.ncbi.nlm.nih.gov

Just-in-Time Adaptive Interventions for Suicide Prevention: Promise, Challenges, and Future Directions. [2023]

7. Switzerland pubmed.ncbi.nlm.nih.gov

The Effectiveness of Mobile Apps for Monitoring and Management of Suicide Crisis: A Systematic Review of the Literature. [2022]

8. United States pubmed.ncbi.nlm.nih.gov

Digital solutions to promote adolescent mental health: Opportunities and challenges for research and practice. [2022]