Your session is about to expire
← Back to Search
Procedure
Surgical Techniques + Gas Tamponade for Retinal Detachment (REDOS Trial)
N/A
Recruiting
Led By Mélanie Hébert, MD MSc
Research Sponsored by CHU de Quebec-Universite Laval
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights
REDOS Trial Summary
This trial will compare two surgical techniques and two gas tamponades to see which are most effective for repairing retinal detachment.
Who is the study for?
This trial is for adults over 18 with a recent diagnosis of rhegmatogenous retinal detachment. It's not suitable for those with advanced proliferative vitreoretinopathy, long-standing detachments over 3 months old, or other complex eye conditions like severe diabetic retinopathy, macular holes, or history of certain eye surgeries.Check my eligibility
What is being tested?
The study compares two surgical methods: pars plana vitrectomy (PPV) alone and PPV combined with scleral buckle. It also tests two types of gas tamponades used in surgery: sulfur hexafluoride (SF6) and perfluoropropane (C3F8). Patients are randomly assigned to one of the surgical techniques and one type of gas.See study design
What are the potential side effects?
Potential side effects may include complications from surgery such as infection, bleeding, increased eye pressure, cataract formation; discomfort from the gas bubble in the eye; and visual disturbances during recovery until the gas is absorbed.
REDOS Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 1 year
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Single surgery anatomic success
Secondary outcome measures
Best-corrected visual acuity
Pinhole visual acuity
Quality of life questionnaire
+2 moreREDOS Trial Design
4Treatment groups
Experimental Treatment
Active Control
Group I: Pars plana vitrectomy with scleral buckle + sulfur hexafluoride gas tamponadeExperimental Treatment2 Interventions
Group II: Pars plana vitrectomy with scleral buckle + perfluoropropane gas tamponadeExperimental Treatment2 Interventions
Group III: Pars plana vitrectomy + perfluoropropane gas tamponadeExperimental Treatment2 Interventions
Group IV: Pars plana vitrectomy + sulfur hexafluoride gas tamponadeActive Control2 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Pars plana vitrectomy
2021
Completed Phase 2
~120
Find a Location
Who is running the clinical trial?
CHU de Quebec-Universite LavalLead Sponsor
167 Previous Clinical Trials
106,597 Total Patients Enrolled
Fighting Blindness CanadaUNKNOWN
Mélanie Hébert, MD MScPrincipal InvestigatorCHU de Québec - Université Laval
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there opportunities for participation in this experiment presently?
"Confirmed. Clinicaltrials.gov presents the trial as currently in its recruitment phase, having been first posted on September 26th 2023 and edited most recently October 2nd 2023."
Answered by AI
What is the current participant capacity of this research project?
"Affirmative. Information made available through clinicaltrials.gov demonstrates that this study, which was originally posted on September 26th 2023 is actively recruiting participants. A total of 560 candidates are needed from a single medical centre."
Answered by AI
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger