Mind-Body Training for Mild Cognitive Impairment
(iMBT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores whether an online mindfulness program can help individuals with early memory concerns, who are at risk for Alzheimer's, improve focus and reduce mind-wandering. Participants will follow either an 8-week mindfulness program (Internet-based Mindfulness-Based Stress Reduction, or iMBSR) or a lifestyle education program (Internet-based Lifestyle Education, or iLifeEd), both completed online at their own pace. It suits those aged 50 or older who notice a decline in memory sharpness but have no diagnosed memory disorders. As an unphased trial, this study provides a unique opportunity to explore innovative approaches to memory improvement without the constraints of traditional clinical trial phases.
Will I have to stop taking my current medications?
The trial requires that participants do not use medications that significantly alter brain activity. If your current medications affect brain activity, you may need to stop taking them to participate.
What prior data suggests that these internet-based programs are safe for adults at-risk for Alzheimer's disease?
Research shows that mindfulness-based stress reduction programs, such as the online iMBSR being tested, are generally safe. Past studies have found these programs improve several health aspects without causing major side effects. Participants often report greater satisfaction with daily activities and improvements in mental well-being.
Mindfulness practices in iMBSR typically include meditation, body scans, and gentle movements. Most people, including older adults, find these activities easy to perform. Although some studies found no significant improvement in thinking skills, they also reported no harm.
In summary, the mindfulness-based approach under study is considered safe based on past research. Participants usually manage it well and may experience benefits like improved mood and increased satisfaction with daily life.12345Why are researchers excited about this trial?
Researchers are excited about Internet-based Mindfulness-Based Stress Reduction (iMBSR) for mild cognitive impairment because it offers a unique approach that emphasizes mindfulness practices delivered digitally. Unlike traditional treatments that may involve medications or in-person therapy, iMBSR allows participants to engage in mindfulness exercises like body scans and meditations at their own pace through an online platform. This flexibility and accessibility can be particularly beneficial for individuals with busy schedules or mobility issues. Additionally, the program fosters a sense of community and support, which can enhance the overall experience and effectiveness of the intervention.
What evidence suggests that this trial's treatments could be effective for mild cognitive impairment?
Research has shown that mindfulness-based stress reduction (MBSR) can enhance thinking skills in older adults. In this trial, participants in the Internet-based Mindfulness-Based Stress Reduction (iMBSR) arm will engage in online mindfulness exercises. Studies have found that these programs can slow memory and thinking problems and improve mental health issues like anxiety and depression. People with mild cognitive impairment, who often struggle with complex tasks, experienced better attention and memory after practicing MBSR. These findings suggest that online MBSR might help those at risk for Alzheimer's disease by boosting brain function and mental well-being.14678
Who Is on the Research Team?
Ruchika S Prakash, PhD
Principal Investigator
Ohio State University
Are You a Good Fit for This Trial?
This trial is for adults aged 50 or older who are experiencing mild cognitive decline and at risk for Alzheimer's disease. Participants must have access to the internet to use the programs. Specific inclusion and exclusion criteria details were not provided.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants engage in an 8-week internet-based program, either iMBSR or iLifeEd, focusing on mindfulness or lifestyle education respectively.
Follow-up
Participants are monitored for changes in cognitive function, stress, quality of life, and AD biomarkers post-intervention.
What Are the Treatments Tested in This Trial?
Interventions
- Internet-based Lifestyle Education (iLifeEd)
- Internet-based Mindfulness-Based Stress Reduction (iMBSR)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ohio State University
Lead Sponsor
National Institute on Aging (NIA)
Collaborator