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Procedure

Abdominal Wall Transplant for Abdominal Wall Defects

N/A
Recruiting
Led By Kadiyala Ravindra, MD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Candidates between 18-65 years old
Abdominal Wall in combination with another organ transplant: they must be eligible for the non-vascularized composite allograft organ transplant at Duke
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 18 months
Awards & highlights

Study Summary

This trial will test whether abdominal wall transplantation is a safe and effective treatment for abdominal wall defects.

Who is the study for?
This trial is for adults aged 18-65 with severe abdominal wall defects, possibly needing an additional organ transplant. Candidates must be able to consent and meet criteria for a non-vascularized composite allograft at Duke. Exclusions include cancer history, pregnancy or potential pregnancy without agreed contraception use, anesthesia risks, and untreated substance abuse.Check my eligibility
What is being tested?
The study is testing the safety and effectiveness of abdominal wall transplants either as a standalone procedure or alongside another solid organ transplant. The goal is to see how well this surgery repairs serious abdominal wall problems.See study design
What are the potential side effects?
Potential side effects may include typical surgical risks such as infection, rejection of the transplanted tissue, complications from general anesthesia, pain at the surgery site, and issues related to long-term immunosuppression.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 18 and 65 years old.
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I am eligible for an organ transplant at Duke, including my abdominal wall.
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I am willing and legally able to consent to participate.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 18 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 18 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Transplantation

Trial Design

2Treatment groups
Experimental Treatment
Group I: Isolated Abdominal Wall TransplantExperimental Treatment1 Intervention
Group II: Abdominal Wall with Solid Organ TransplantExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

Duke UniversityLead Sponsor
2,356 Previous Clinical Trials
3,409,096 Total Patients Enrolled
4 Trials studying Kidney Failure
1,595 Patients Enrolled for Kidney Failure
Linda Cendales, MDUNKNOWN
Detlev Erdmann, M.D.UNKNOWN

Media Library

Abdominal Wall Transplant (Procedure) Clinical Trial Eligibility Overview. Trial Name: NCT03310905 — N/A
Kidney Failure Research Study Groups: Isolated Abdominal Wall Transplant, Abdominal Wall with Solid Organ Transplant
Kidney Failure Clinical Trial 2023: Abdominal Wall Transplant Highlights & Side Effects. Trial Name: NCT03310905 — N/A
Abdominal Wall Transplant (Procedure) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03310905 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To which patient demographic does this investigation extend?

"This research requires potential subjects to possess a hernia, ventral and be between 18-65 years of age. A maximum of 5 participants can join this clinical trial."

Answered by AI

Has the FDA greenlit Abdominal Wall Transplantation?

"Abdominal Wall Transplant has been given a rating of 2 on our scale, indicating that there is some evidence for its safety but no data yet to support its efficacy."

Answered by AI

Are there any open enrollment opportunities for this research study?

"Affirmative. According to information available on clinicaltrials.gov, this research is presently looking for participants and has been doing so since May 1st 2018. It was last updated on January 18th 2022 and requires 5 volunteers from a single site of recruitment."

Answered by AI

Is the age cutoff for this trial inclusive of those under 25 years old?

"This medical trial is recruiting those aged 18 to 65; however, there are 36 trials that cater specifically to minors and 392 studies open for seniors."

Answered by AI

How many participants have registered for this research project?

"Affirmative. The information stored on clinicaltrials.gov demonstrates that this trial is currently seeking participants, with its inaugural posting having been made on May 1st 2018 and the most recent update occuring in January 18th 2022. Five individuals need to be recruited from only one location for successful completion of this study."

Answered by AI
~2 spots leftby Jan 2028