HP 129Xe MRI for Lung Function Assessment
(HpXeMRCal Trial)
Trial Summary
What is the purpose of this trial?
The goal of this study is to evaluate the usefulness of hyperpolarized (HP) 129Xe (xenon) gas MRI for regional assessment of lung function in a normal population of adults for the purposes of obtaining optimal images through MRI.
Do I need to stop taking my current medications for the trial?
The trial protocol does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment HP 129Xe MRI for lung function assessment?
Research shows that HP 129Xe MRI is effective in assessing lung function by providing detailed images of how air moves and exchanges in the lungs. This imaging technique has been promising in evaluating lung diseases and is gaining attention for its ability to visualize lung ventilation and gas transfer.12345
Is HP 129Xe MRI safe for humans?
The safety of MRI, including HP 129Xe MRI, is generally well-established as it does not use ionizing radiation. However, strong magnetic fields require specific safety measures, and the American College of Radiology provides guidelines to ensure safe use. No specific safety data for HP 129Xe MRI is mentioned, but general MRI safety standards apply.678910
How is HP 129Xe MRI different from other lung function assessments?
HP 129Xe MRI is unique because it uses hyperpolarized xenon gas to provide detailed images of lung ventilation and gas exchange, offering insights into both the structure and function of the lungs. Unlike traditional imaging methods, it can assess regional lung physiology and is particularly promising for managing lung diseases, including lung cancer.12345
Research Team
Jason C Woods, Ph.D.
Principal Investigator
Children's Hospital Medical Center, Cincinnati
Eligibility Criteria
This trial is for adults who can hold their breath for up to 16 seconds. It's not suitable for those with heart defects, uncontrolled asthma, low oxygen levels without support, or recent respiratory infections. Pregnant individuals and those with MRI-incompatible implants are also excluded.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Imaging Session
Participants undergo MRI scans with hyperpolarized 129Xe gas to assess lung function
Follow-up
Participants are monitored for safety and effectiveness after imaging
Treatment Details
Interventions
- Hyperpolarized 129 Xenon
- MRI
Find a Clinic Near You
Who Is Running the Clinical Trial?
Children's Hospital Medical Center, Cincinnati
Lead Sponsor