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Nicotinamide Riboside for Sarcopenia (NR-VET Trial)
NR-VET Trial Summary
This trial will test whether nicotinamide riboside, a form of vitamin B3, is safe and effective in improving muscle function and physiology in humans.
NR-VET Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowNR-VET Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.NR-VET Trial Design
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Who is running the clinical trial?
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- Your VA-SLUMS cognitive screen score is 20 or lower.I have chronic kidney disease stage 3 or higher.I have severe COPD.I am either male or female.You are very overweight, with a body mass index of 40 or higher.I am between 65 and 85 years old.I am cleared by a doctor to have a muscle biopsy.My heart condition significantly limits my physical activity.You have a serious other health condition.You are able to use a stationary exercise bike.
- Group 1: NR Supplementation
- Group 2: Placebo supplementation
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the age limit for trial enrollment beyond thirty years of age?
"This research is open to senior citizens aged between 65 and 85."
Does this experiment have any open slots for participants?
"According to the information posted on clinicaltrials.gov, this study is no longer open for applicants. It was first announced on January 15th 2023 but has since been edited as of November 8th 2022 and closed off recruitment. Nonetheless, there are currently 105 other trials actively looking for participants right now."
What objectives are being pursued with this clinical experiment?
"This clinical trial will be evaluated over a 12-week period, with the goal of measuring maximal oxygen uptake (VO2max). Secondary outcomes include body composition assessed through bioelectric impedance (BIA), muscle analysis including NAD+ content and mitochondrial health, messageRNA expression changes in response to treatment, and quality of life assessment using the Quality of Life Enjoyment & Satisfaction Questionnaire - Short Form (Q-LES-Q-SF) survey instrument."
Am I eligible for entry into this research program?
"To qualify for this trial, prospective participants must meet the following criteria: Gender (male or female), Capacity to cycle on a stationary bike, Age range of 65-85 years old and No racial restriction. Ultimately, 144 people with sarcopenia are being sought."
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