Time restricted feeding for Type 2 Diabetes Mellitus

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
OhioHealth Castrop Health Center, Athens, OH
Type 2 Diabetes Mellitus+2 More
Time restricted feeding - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Select

Study Summary

Application of Time Restriction Feeding in Patients With Type 2 Diabetes Mellitus

See full description

Eligible Conditions

  • Type 2 Diabetes Mellitus

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Type 2 Diabetes Mellitus

Study Objectives

This trial is evaluating whether Time restricted feeding will improve 2 primary outcomes and 3 secondary outcomes in patients with Type 2 Diabetes Mellitus. Measurement will happen over the course of in one week of time restricted feeding.

in one week of time restricted feeding
Insulin resistance
body weight
estimated hemoglobin A1c levels
mean glucose
serum triglyceride levels

Trial Safety

Safety Progress

1 of 3

Other trials for Type 2 Diabetes Mellitus

Trial Design

1 Treatment Group

Time restricted feeding
1 of 1
Experimental Treatment

This trial requires 30 total participants across 1 different treatment group

This trial involves a single treatment. Time Restricted Feeding is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Time restricted feeding
Behavioral
The study will consist of three phases. In phase I all study subjects will be in the ad libitum feeding phase for one week followed by Phase II. In Phase II the subjects will be placed on time-restricted fasting (feeding between 4 AM - 4 PM, fasting in the rest of the day) for one week. For phase III (final week), patients will be returned to an ad libitum feeding. The first and third phases will serve as control phases, and the second phase will be the experimental phase
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Time restricted feeding
2019
N/A
~760

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: in one week of time restricted feeding
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly in one week of time restricted feeding for reporting.

Closest Location

OhioHealth Castrop Health Center - Athens, OH

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 5 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
With the diagnosis of type 2 diabetes
A1c >= 8.0 on the most recent test in the 3 months before enrollment
Have been on stable antidiabetics in the 3 months before enrollment
Age ≥ 18 years and < 65 years
OhioHealth Patient

Patient Q&A Section

Can diabetes mellitus, type 2 be cured?

"The answer is no. Treating diabetes mellitus, type 2 has no effect on the course or the incidence of its complications, even though it prolongs the course of complications of diabetes mellitus." - Anonymous Online Contributor

Unverified Answer

What are common treatments for diabetes mellitus, type 2?

"There is a need for education and research in the development of diabetes therapies. Antioxidant use and/or aspirin use can provide protection against the adverse effects of diabetes and its complications." - Anonymous Online Contributor

Unverified Answer

What is diabetes mellitus, type 2?

"The most commonly reported diabetes-specific symptom in women aged ≥40 years is 'bloodsugar problems' (95.4 %). Other symptom types reported include frequent urination (72 %), feeling tired (40.7 %), or blurred vision (40.7 %)." - Anonymous Online Contributor

Unverified Answer

What causes diabetes mellitus, type 2?

"The risk of developing or progressing T2DM is increased substantially in adolescents and persons in their early 50s. Furthermore, the risk increases with the duration between a person's first diabetes diagnosis and subsequent diagnosis in the T2DM group and decreases with increased age among those diagnosed with T1DM and T2DM." - Anonymous Online Contributor

Unverified Answer

What are the signs of diabetes mellitus, type 2?

"Most people with diabetes have no signs or symptoms of their condition until they are symptomatic, which is typically with regard to high blood glucose levels. It is therefore worthwhile for diabetics to consider and manage their blood glucose levels appropriately. Diabetics who are overweight have a higher rate of diabetic complications and are at a higher risk for coronary heart disease than those of normal weight." - Anonymous Online Contributor

Unverified Answer

How many people get diabetes mellitus, type 2 a year in the United States?

"The number of cases among the United States population is expected to increase by 5% between 2000 and 2050. Diabetes mellitus, type 2 is a significant burden to society." - Anonymous Online Contributor

Unverified Answer

How does time restricted feeding work?

"In clinical trials in the context of type two T1DM, only a small number of patients remain in remission over a year. This highlights the need for further long term follow up, as a few patients who have gone untreated do not achieve remission after a year. Time restricted feeding remains a viable option for long term control in T1DM patients." - Anonymous Online Contributor

Unverified Answer

What is time restricted feeding?

"The mean preoperative fasting period in diabetic patients from our cohort was 1 hour 20 min, while an overnight fast was recommended for patients with severe diabetes mellitus at least 65 years of age." - Anonymous Online Contributor

Unverified Answer

How serious can diabetes mellitus, type 2 be?

"Although the overall impact of CVD risk factors on mortality is high in T2DM patients, a large proportion of them remain at low or moderate cardiovascular mortality risk. It will be important to continue to monitor CVD risk factor-adjusted cardiovascular mortality in T2DM patients to inform public health guidelines and help improve prevention strategies of CVD in T2DM patients." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating diabetes mellitus, type 2?

"There have been a series of research papers published since 2001, which may help explain how we are now able to treat and prevent diabetes mellitus, type 2. More research is needed in the future to explain the many issues about managing these diseases that remain. Although there are many ways to manage diabetes mellitus, type 2, there are a number of treatments that can be useful in preventing or managing symptoms of complications associated with this disease." - Anonymous Online Contributor

Unverified Answer

What is the primary cause of diabetes mellitus, type 2?

"Data from a recent study indicate that an increase in the incidence of diabetes is caused by increasing levels of BMI and decreasing insulin sensibility and may not be directly related to changes in body weight. The decrease in insulin sensitivity is likely to contribute to the rise in BMI." - Anonymous Online Contributor

Unverified Answer

What are the common side effects of time restricted feeding?

"Results from a recent paper, we identified some important side effects due to time restricted dietary interventions that are not well known among lay people and have not been assessed in studies on nutrition and complementary medicine." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
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