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Azithromycin for Meibomian Gland Dysfunction
Study Summary
This trial will study whether azithromycin can treat dry eye syndrome caused by Meibomian gland dysfunction.
- Neuropathic Eye Pain
- Dry Eye Syndrome
- Ocular Microbiome
- Depression and Anxiety
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- You are allergic to the preservatives in the 0.1% dexamethasone eye drops.You have a history of heart rhythm problems or heart failure.You are currently taking medications that can affect your heart's rhythm.You are allergic or intolerant to taking azithromycin by mouth or using dexamethasone on your skin.You have very low tear production, measured by a specific test.You have an eye condition that causes inflammation on the surface of your eyes.You have an allergic condition that affects your eyes.You are taking more than 5mg of prednisone by mouth every day.You have used steroid eye drops in the last 30 days.You have used any eye drops for inflammation in the last 30 days.Your OSDI score is 20 or more.You have a condition called limbal stem cell deficiency.You have used oral or eye antibiotics in the last 90 days.You have noticeable eye discomfort along with a specific level of Meibomian gland disease.
- Group 1: Placebo
- Group 2: Azithromycin
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 30 Other Conditions - This treatment demonstrated efficacy for 30 other conditions.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is there a precedent for the utilization of Azithromycin in clinical trials?
"Currently, there are 55 ongoing experiments that focus on Azithromycin. These trials span 694 sites across the globe; 18 of these studies lie in Phase 3. Unsurprisingly, Albuquerque has a high concentration of clinical trials for this drug."
Is participation in this trial still an option for those seeking treatment?
"Proven to be true, according to clinicaltrials.gov, this research is actively recruiting for participants. First announced on September 1st 2018 and most recently updated on January 29th 2021, the study requires 40 people from a single location."
What is the projected scale of this clinical research endeavor?
"Indeed, the information available on clinicaltrials.gov confirms that this trial is actively searching for participants. The research was posted in September 2018 and updated at the end of January 2021; it requires 40 patients who will be recruited from one medical centre."
What medical conditions typically call for Azithromycin as a treatment?
"Azithromycin is the recommended treatment for genital ulcer disease (GUD) and also helps alleviate chlamydia, adult infections, and cervicitis."
What potential risks do individuals face when taking Azithromycin?
"The safety of azithromycin has been thoroughly assessed and is rated at a 3, as it was approved in the fourth phase of testing."
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