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non-invasive Meibomian gland (MG) expression for Meibomian Gland Dysfunction

N/A
Waitlist Available
Research Sponsored by University of the Incarnate Word
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Healthy individuals with reported symptoms of dry eye such as burning, stinging, fluctuating vision, inappropriate tearing, and feelings of grittiness particularly with prolonged near work
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up this test will occur prior to the intervention (meibomian gland expression) and immediately after this intervention.
Awards & highlights

Study Summary

This trial explores how MGD dry eye affects sight & how non-invasive MG expression can improve vision.

Eligible Conditions
  • Meibomian Gland Dysfunction

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
Healthy individuals with symptoms of dry eye such as burning, stinging, blurry vision, excessive tearing, and feeling like there is something in your eye, especially after prolonged reading or using screens.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~this test will occur prior to the intervention (meibomian gland expression) and immediately after this intervention.
This trial's timeline: 3 weeks for screening, Varies for treatment, and this test will occur prior to the intervention (meibomian gland expression) and immediately after this intervention. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Cone Contrast Sensitivity on the Cone Contrast Test (CCT, Innova Systems, Inc.)
Change in Response Time on Cone Contrast Test (CCT, Innova Systems, Inc.)
Secondary outcome measures
Change in Black White Contrast Sensitivity (Innova Systems, Inc)
Change in Color Naming Accuracy on Cone Contrast Color Naming test (CCNT)
Change in Response Time on Black White Contrast Sensitivity Test (Innova Systems, Inc) Response Time
+3 more
Other outcome measures
Change in High Contrast Visual Acuity
Change in Small Letter Contrast Sensitivity

Trial Design

1Treatment groups
Experimental Treatment
Group I: non-invasive Meibomian gland (MG) expressionExperimental Treatment1 Intervention
Baseline testing of visual acuity, contrast sensitivity, color vision, and Innova, Inc. cone and B/W low contrast vision will be measured. The intervention will be standard clinical expression of Meibomian superior and inferior glands (MG) using a sterile cotton tip applicator to apply gentle pressure in a rolling motion in the direction of the MGs along the upper and lower eyelid margins to allow oil secretion of the tested eye. One drop of sterile saline will be instilled following the intervention to remove debris. The subject's visual acuity, contrast sensitivity, color vision, and Innova, Inc. cone and B/W low contrast vision will be measured before and after this intervention.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Meibomian gland (MG) expression
2023
N/A
~40

Find a Location

Who is running the clinical trial?

University of the Incarnate WordLead Sponsor
17 Previous Clinical Trials
2,539 Total Patients Enrolled
4 Trials studying Meibomian Gland Dysfunction
131 Patients Enrolled for Meibomian Gland Dysfunction
Jeffery Rabin, OD, PhDStudy ChairUniversity of the Incarnate Word

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research still actively recruiting participants?

"This research is not presently recruiting participants. Originally posted to clinicaltrials.gov on February 6th, 2023 and updated lastly on the 1st of February in that same year, this trial is no longer accepting candidates at present; however there are 84 other studies actively searching for volunteers now."

Answered by AI

What are the chief aims of this medical experiment?

"This research endeavour has the purpose of measuring a change in Response Time on Cone Contrast Test (CCT, Innova Systems, Inc.) over an allocated time period. Supplementary outcomes monitored include Change in Response Time on Black White Contrast Sensitivity Test (Innova Systems, Inc) which gauges reaction speed to low contrast black/white letters; Change in Visual Acuity Test at Low Contrast (Innova Systems, Inc), used for evaluating minimal visible low contrast characters; and Change in Response Time on Visual Acuity Test at Low Contrast (Innova Systems, Inc) which assesses average response time when identifying small scale visual acuity symbols"

Answered by AI

Who else is applying?

What state do they live in?
Texas
What site did they apply to?
University of the Incarnate Word Rosenberg School of Optometry
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
1

Why did patients apply to this trial?

My dry eyes are bothering me a lot. Burning, itchy, swollen.
PatientReceived 2+ prior treatments
~20 spots leftby Mar 2025