Your session is about to expire
← Back to Search
Semaglutide for Type 2 Diabetes (TRANSITION-T2D Trial)
TRANSITION-T2D Trial Summary
This trial will compare the effects of semaglutide + insulin degludec vs. insulin degludec alone in people with type 2 diabetes who are already taking insulin injections.
- Type 2 Diabetes
TRANSITION-T2D Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.TRANSITION-T2D Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- You are taking a combination of GLP-1RA (like IGlarLixi or IDegLira) with basal insulin.You have a history of pancreatitis or severe liver disease, or your liver function tests are more than 2.5 times the upper limit of normal. You also have a severe disease affecting your digestive tract.You have known allergies to the trial medication or related products like GLP-1RA therapy, insulin aspart, or insulin degludec.You or someone in your family has a condition called Multiple Endocrine Neoplasia syndrome type 2.You or someone in your family has had medullary thyroid carcinoma (a type of thyroid cancer).
- Group 1: Once-weekly sc semaglutide combined with once-daily insulin
- Group 2: MDI requiring multiple daily injections of insulin
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
What side effects, if any, have been observed from the use of Semaglutide?
"An analysis conducted by Power assigned Semaglutide a score of 3, as this Phase 4 trial has yielded positive results and the medication is now approved for public use."
Are there currently any slots available for participation in this clinical trial?
"Affirmative. According to clinicaltrials.gov, this experiment is actively seeking participants and has been listed since 18th of January 2021. Subsequent updates were made on the 18th of July 2022. The research team are looking for 100 volunteers from just one site."
What medical challenges has Semaglutide been utilized to address?
"Semaglutide has the potential to help patients manage exercise, type 1 diabetes mellitus, and other diseases."
Is there any precedent for this type of trial?
"Currently, 788 cities and 56 countries host 75 live Semaglutide studies. The first trial for the drug was sponsored by Hamad Medical Corporation in 2016 with 150 participants; since then, there have been 563 additional trials conducted."
What other research endeavors have been launched regarding Semaglutide?
"Currently, there are 33 Phase 3 trials for Semaglutide being conducted worldwide with a total of 4102 trial sites. Of these studies, 75 remain active and several have been initiated in Herlev, Texas."
Who is eligible for involvement in this experiment?
"This clinical trial seeks 100 individuals, aged 18 to 75 years old, with type 2 diabetes mellitus. To be eligible for the study one must fulfill a range of criteria including: gender (both men and women), ethnicity (all ethnicities are accepted), language (English-speaking only), A1C ≤ 7.5% on present therapy, therapies involving three or more insulin injections per day—with at least two being prandial/rapid-acting varieties like Insulin Aspart, Glulisine or Lispro; as well as single daily doses of long-acting analogues such as Insulin Glargine U-"
Are persons aged 75 years or younger being taken into consideration for this experiment?
"This clinical trial is open to patients aged 18-75. There are 205 studies for minors and 1163 trials aimed at those over 65 years old."
How many individuals are being recruited for participation in this research?
"Affirmative. According to the clinicaltrials.gov webpage, this medical research is recruiting participants as of now - it was initially posted on January 18th 2021 and lastly revised on July 18th 2022. The study requires 100 subjects from a single site."
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger