Test Arm for Type 2 Diabetes

Geisinger Medical Center, Danville, PA
Type 2 DiabetesSemaglutide (1 Mg Dose) - Drug
Eligibility
18 - 75
All Sexes
What conditions do you have?
Select

Study Summary

This trial is for patients with diabetes who require insulin for glycemic control and are undergoing bariatric surgery. It is trying to determine if the semaglutide will increase remission rates of diabetes post-operatively.

Treatment Effectiveness

Phase-Based Effectiveness

3 of 3
Phase 4
This is further along than 93% of similar trials

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: 11 months

11 months
RATE OF COMPLETE REMISSION OF DIABETES
RATE OF PARTIAL REMISSION OF DIABETES

Trial Safety

Phase-Based Safety

3 of 3
This is further along than 85% of similar trials

Awards & Highlights

Drug Has Already Been Approved
The FDA has already approved this drug, and is just seeking more data.
Pivotal Trial
The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 10 Other Conditions
This treatment demonstrated efficacy for 10 other conditions.

Trial Design

2 Treatment Groups

Test Arm
1 of 2
Control Arm
1 of 2

Active Control

Non-Treatment Group

3 Total Participants · 2 Treatment Groups

Primary Treatment: Test Arm · Has Placebo Group · Phase 4

Control Arm
Drug
PlaceboComparator Group · 1 Intervention: Placebo · Intervention Types: Drug
Test Arm
Drug
ActiveComparator Group · 1 Intervention: Semaglutide (1 Mg Dose) · Intervention Types: Drug

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 11 months

Who is running the clinical trial?

Geisinger ClinicLead Sponsor
141 Previous Clinical Trials
2,288,932 Total Patients Enrolled
Novo Nordisk A/SIndustry Sponsor
1,436 Previous Clinical Trials
2,332,069 Total Patients Enrolled
Christopher Still, DOPrincipal InvestigatorGeisinger Clinic

Eligibility Criteria

Age 18 - 75 · All Participants · 2 Total Inclusion Criteria

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Frequently Asked Questions

What type of ailment does Test Arm usually alleviate?

"The most common use for Test Arm is to help people manage their weight over the long term. Additionally, it can be used as part of a treatment plan that includes diet and exercise changes to mitigate other obesity-related health concerns." - Anonymous Online Contributor

Unverified Answer

Do you have an age limit for the individuals who can take part in this research?

"This study allows for patients that are between 18-75 years old, as these are the age limits set in the eligibility criteria." - Anonymous Online Contributor

Unverified Answer

Has the Test Arm undergone FDA approval?

"The safety of Test Arm is estimated to be a 3. This can be attributed to the fact that this treatment is approved because it is a Phase 4 trial." - Anonymous Online Contributor

Unverified Answer

Who would this clinical trial be appropriate for?

"Candidates that have type 2 diabetes mellitus and are aged between 18 to 75 years old may qualify for this clinical trial. The study intends to enroll 126 patients in total." - Anonymous Online Contributor

Unverified Answer

Is this clinical trial novel in its approach?

"Test Arm is being used in 58 different ongoing studies, located across 769 cities and 55 countries. The first study using Test Arm was completed in 2018 as part of Novo Nordisk A/S's Phase 4 drug approval stage. That trial involved 1387 patients. In the years since 2018, 18403 trials have been completed worldwide." - Anonymous Online Contributor

Unverified Answer

How many subjects are enrolled in this research?

"The listing on clinicaltrials.gov supports that this research is ongoing and seeking patients. The trial was established on August 25th, 2021 with the most recent update being September 9th, 2021. They are looking for 126 individuals total across 1 centre." - Anonymous Online Contributor

Unverified Answer

Are people still able to join this research project?

"Yes, this trial is currently seeking patients. According to the listings on clinicaltrials.gov, the initial posting was on 8/25/2021 with a most recent update of 9/9/2021. The trial needs 126 total subjects and is only looking at 1 site right now." - Anonymous Online Contributor

Unverified Answer

Are there other instances where Test Arm has been used in research?

"Currently, there are 27 phase 3 trials and 58 active studies investigating Test Arm. Many of these clinical tests for Test Arm are based in Loma Linda, California; however, there are 3901 locations conducting trials for Test Arm." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.